简单的代码，让你与多个项目的差异，如果你想要:

a=[1,2,3,3,4]
b=[2,4]
tmp = copy.deepcopy(a)
for k in b:
    if k in tmp:
        tmp.remove(k)
print(tmp)

如果顺序无关紧要，你可以简单地计算集合差值:

>>> set([1,2,3,4]) - set([2,5])
set([1, 4, 3])
>>> set([2,5]) - set([1,2,3,4])
set([5])

如果你不关心项目的顺序或重复，请使用set。使用列表推导式:

>>> def diff(first, second):
        second = set(second)
        return [item for item in first if item not in second]

>>> diff(A, B)
[1, 3, 4]
>>> diff(B, A)
[5]
>>> 

有三种选择，其中两种是可以接受的，另一种不应该这样做。

在较高的级别上，这3个选项是:

减去两组(有时最好) 检查每个列表项是否存在于一个集合中(大多数情况下最好) 检查每个列表项是否存在于列表中(不做)

选项3)永远不应该超过选项2)。根据应用程序的需要，您可能更喜欢选项1)或2)，而在大多数用例中，2)可能是首选方法。2)与1)的性能非常相似，因为两者都具有O(m + n)个时间复杂度。相比之下，2)在空间复杂度上比1)有边际优势，并且既保持了原始列表的顺序，又保持了原始列表中的任何重复。

如果你想删除重复，不关心顺序，那么1)可能是最适合你的。

import time

def fun1(l1, l2):
    # Order and duplications in l1 are both lost, O(m) + O(n)
    return set(l1) - set(l2)

def fun2(l1, l2):
    # Order and duplications in l1 are both preserved, O(m) + O(n)
    l2_set = set(l2)
    return [item for item in l1 if item not in l2_set]

def fun3(l1, l2):
    # Order and duplications in l1 are both preserved, O(m * n)
    # Don't do
    return [item for item in l1 if item not in l2]

A = list(range(7500))
B = list(range(5000, 10000))

loops = 100

start = time.time()
for _ in range(loops):
    fun1(A, B)
print(f"fun1 time: {time.time() - start}")

start = time.time()
for _ in range(loops):
    fun2(A, B)
print(f"fun2 time: {time.time() - start}")

start = time.time()
for _ in range(loops):
    fun3(A, B)
print(f"fun3 time: {time.time() - start}")

fun1 time: 0.03749704360961914
fun2 time: 0.04109621047973633
fun3 time: 32.55076885223389

当查看in -operator的TimeComplexity时，在最坏的情况下它与O(n)一起工作。即使是集合。

因此，当比较两个数组时，最好情况下的TimeComplexity为O(n)，最坏情况下为O(n²)。

另一种(但不幸的是更复杂)解决方案，在最好和最坏的情况下都适用于O(n):

# Compares the difference of list a and b
# uses a callback function to compare items
def diff(a, b, callback):
  a_missing_in_b = []
  ai = 0
  bi = 0

  a = sorted(a, callback)
  b = sorted(b, callback)

  while (ai < len(a)) and (bi < len(b)):

    cmp = callback(a[ai], b[bi])
    if cmp < 0:
      a_missing_in_b.append(a[ai])
      ai += 1
    elif cmp > 0:
      # Item b is missing in a
      bi += 1
    else:
      # a and b intersecting on this item
      ai += 1
      bi += 1

  # if a and b are not of same length, we need to add the remaining items
  for ai in xrange(ai, len(a)):
    a_missing_in_b.append(a[ai])


  return a_missing_in_b

e.g.

>>> a=[1,2,3]
>>> b=[2,4,6]
>>> diff(a, b, cmp)
[1, 3]

A = [1,2,3,4]
B = [2,5]

#A - B
x = list(set(A) - set(B))
#B - A 
y = list(set(B) - set(A))

print x
print y