import time
seconds_since_epoch = time.mktime(your_datetime.timetuple()) * 1000

Python 2.7文档对time模块的建议

很多答案在python2中不起作用，或者没有从datetime中保存毫秒。这对我很有用

def datetime_to_ms_epoch(dt):
    microseconds = time.mktime(dt.timetuple()) * 1000000 + dt.microsecond
    return int(round(microseconds / float(1000)))

下面是一个基于上面答案的函数

def getDateToEpoch(myDateTime):
    res = (datetime.datetime(myDateTime.year,myDateTime.month,myDateTime.day,myDateTime.hour,myDateTime.minute,myDateTime.second) - datetime.datetime(1970,1,1)).total_seconds()
    return res

你可以像这样包装返回值: 返回不带十进制值的字符串或只是int(不带str)

在我看来，最简单的方法是

import datetime

epoch = datetime.datetime.utcfromtimestamp(0)

def unix_time_millis(dt):
    return (dt - epoch).total_seconds() * 1000.0

这是将datetime转换为unixtimestampmillis的另一个解决方案。

private static readonly DateTime UnixEpoch = new DateTime(1970, 1, 1, 0, 0, 0, DateTimeKind.Utc);

    public static long GetCurrentUnixTimestampMillis()
    {
        DateTime localDateTime, univDateTime;
        localDateTime = DateTime.Now;          
        univDateTime = localDateTime.ToUniversalTime();
        return (long)(univDateTime - UnixEpoch).TotalMilliseconds;
    }