我是这样做的:

from datetime import datetime
from time import mktime

dt = datetime.now()
sec_since_epoch = mktime(dt.timetuple()) + dt.microsecond/1000000.0

millis_since_epoch = sec_since_epoch * 1000

一段熊猫代码:

import pandas

def to_millis(dt):
    return int(pandas.to_datetime(dt).value / 1000000)

下面是一个基于上面答案的函数

def getDateToEpoch(myDateTime):
    res = (datetime.datetime(myDateTime.year,myDateTime.month,myDateTime.day,myDateTime.hour,myDateTime.minute,myDateTime.second) - datetime.datetime(1970,1,1)).total_seconds()
    return res

你可以像这样包装返回值: 返回不带十进制值的字符串或只是int(不带str)

>>> import datetime
>>> # replace datetime.datetime.now() with your datetime object
>>> int(datetime.datetime.now().strftime("%s")) * 1000 
1312908481000

或者时间模块的帮助(没有日期格式):

>>> import datetime, time
>>> # replace datetime.datetime.now() with your datetime object
>>> time.mktime(datetime.datetime.now().timetuple()) * 1000
1312908681000.0

得到了来自:http://pleac.sourceforge.net/pleac_python/datesandtimes.html的帮助

文档:

time.mktime datetime.timetuple

你可以用德罗宁去时空旅行!

import datetime
import delorean
dt = datetime.datetime.utcnow()
delorean.Delorean(dt, timezone="UTC").epoch

http://delorean.readthedocs.org/en/latest/quickstart.html  

import time
seconds_since_epoch = time.mktime(your_datetime.timetuple()) * 1000