由于其他答案对我都没有帮助，我建议这样做。它在Internet Explorer 8中对我有效：

if (typeof variable_name.value === 'undefined') {
    // variable_name is undefined
}

如果未定义，它将不等于包含字符“undefined”的字符串，因为该字符串未定义。

您可以检查变量的类型：

if (typeof(something) != "undefined") ...

有时你甚至不必检查类型。如果变量的值在设置时不能求值为false（例如，如果它是一个函数），那么可以只对变量求值。例子：

if (something) {
  something(param);
}

您可以使用typeof，如下所示：

if (typeof something != "undefined") {
    // ...
}

在本文中，我了解到Undercore.js等框架使用此函数：

function isUndefined(obj){
    return obj === void 0;
}

我使用它作为函数参数，并在函数执行时排除它，这样我就得到了未定义的“真实”。尽管它确实需要您将代码放在函数中。我在阅读jQuery源代码时发现了这一点。

undefined = 2;

(function (undefined) {
   console.log(undefined); // prints out undefined
   // and for comparison:
   if (undeclaredvar === undefined) console.log("it works!")
})()

当然，你可以使用typeof。但无论如何，我的所有代码通常都在一个包含函数中，所以使用这个方法可能会在这里和那里节省一些字节。

说明各种答案结果的一些场景：http://jsfiddle.net/drzaus/UVjM4/

（请注意，在测试中使用var会在作用域包装器中产生差异）

参考代码：

(function(undefined) {
    var definedButNotInitialized;
    definedAndInitialized = 3;
    someObject = {
        firstProp: "1"
        , secondProp: false
        // , undefinedProp not defined
    }
    // var notDefined;

    var tests = [
        'definedButNotInitialized in window',
        'definedAndInitialized in window',
        'someObject.firstProp in window',
        'someObject.secondProp in window',
        'someObject.undefinedProp in window',
        'notDefined in window',

        '"definedButNotInitialized" in window',
        '"definedAndInitialized" in window',
        '"someObject.firstProp" in window',
        '"someObject.secondProp" in window',
        '"someObject.undefinedProp" in window',
        '"notDefined" in window',

        'typeof definedButNotInitialized == "undefined"',
        'typeof definedButNotInitialized === typeof undefined',
        'definedButNotInitialized === undefined',
        '! definedButNotInitialized',
        '!! definedButNotInitialized',

        'typeof definedAndInitialized == "undefined"',
        'typeof definedAndInitialized === typeof undefined',
        'definedAndInitialized === undefined',
        '! definedAndInitialized',
        '!! definedAndInitialized',

        'typeof someObject.firstProp == "undefined"',
        'typeof someObject.firstProp === typeof undefined',
        'someObject.firstProp === undefined',
        '! someObject.firstProp',
        '!! someObject.firstProp',

        'typeof someObject.secondProp == "undefined"',
        'typeof someObject.secondProp === typeof undefined',
        'someObject.secondProp === undefined',
        '! someObject.secondProp',
        '!! someObject.secondProp',

        'typeof someObject.undefinedProp == "undefined"',
        'typeof someObject.undefinedProp === typeof undefined',
        'someObject.undefinedProp === undefined',
        '! someObject.undefinedProp',
        '!! someObject.undefinedProp',

        'typeof notDefined == "undefined"',
        'typeof notDefined === typeof undefined',
        'notDefined === undefined',
        '! notDefined',
        '!! notDefined'
    ];

    var output = document.getElementById('results');
    var result = '';
    for(var t in tests) {
        if( !tests.hasOwnProperty(t) ) continue; // bleh

        try {
            result = eval(tests[t]);
        } catch(ex) {
            result = 'Exception--' + ex;
        }
        console.log(tests[t], result);
        output.innerHTML += "\n" + tests[t] + ": " + result;
    }
})();

结果：

definedButNotInitialized in window: true
definedAndInitialized in window: false
someObject.firstProp in window: false
someObject.secondProp in window: false
someObject.undefinedProp in window: true
notDefined in window: Exception--ReferenceError: notDefined is not defined
"definedButNotInitialized" in window: false
"definedAndInitialized" in window: true
"someObject.firstProp" in window: false
"someObject.secondProp" in window: false
"someObject.undefinedProp" in window: false
"notDefined" in window: false
typeof definedButNotInitialized == "undefined": true
typeof definedButNotInitialized === typeof undefined: true
definedButNotInitialized === undefined: true
! definedButNotInitialized: true
!! definedButNotInitialized: false
typeof definedAndInitialized == "undefined": false
typeof definedAndInitialized === typeof undefined: false
definedAndInitialized === undefined: false
! definedAndInitialized: false
!! definedAndInitialized: true
typeof someObject.firstProp == "undefined": false
typeof someObject.firstProp === typeof undefined: false
someObject.firstProp === undefined: false
! someObject.firstProp: false
!! someObject.firstProp: true
typeof someObject.secondProp == "undefined": false
typeof someObject.secondProp === typeof undefined: false
someObject.secondProp === undefined: false
! someObject.secondProp: true
!! someObject.secondProp: false
typeof someObject.undefinedProp == "undefined": true
typeof someObject.undefinedProp === typeof undefined: true
someObject.undefinedProp === undefined: true
! someObject.undefinedProp: true
!! someObject.undefinedProp: false
typeof notDefined == "undefined": true
typeof notDefined === typeof undefined: true
notDefined === undefined: Exception--ReferenceError: notDefined is not defined
! notDefined: Exception--ReferenceError: notDefined is not defined
!! notDefined: Exception--ReferenceError: notDefined is not defined