我偶然发现了与op类似的问题。不幸的是，接受的答案不适合我，因为collectionView的内容不会正确居中。因此，我提出了一个不同的解决方案，只需要在collectionView中的所有项目都具有相同的宽度，这似乎是问题中的情况:

#define cellSize 90

- (UIEdgeInsets)collectionView:(UICollectionView *)collectionView layout:(UICollectionViewLayout *)collectionViewLayout insetForSectionAtIndex:(NSInteger)section {
    float width = collectionView.frame.size.width;
    float spacing = [self collectionView:collectionView layout:collectionViewLayout minimumInteritemSpacingForSectionAtIndex:section];
    int numberOfCells = (width + spacing) / (cellSize + spacing);
    int inset = (width + spacing - numberOfCells * (cellSize + spacing) ) / 2;

    return UIEdgeInsetsMake(0, inset, 0, inset);
}

该代码将确保…minimumInteritemSpacing…将是每个collectionViewCell之间的精确间距，并进一步保证所有的单元格一起将在collectionView

在头文件中定义UICollectionViewDelegateFlowLayout协议。

实现UICollectionViewDelegateFlowLayout协议的如下方法:

- (UIEdgeInsets)collectionView:(UICollectionView *)collectionView layout:(UICollectionViewLayout*)collectionViewLayout insetForSectionAtIndex:(NSInteger)section
{
    return UIEdgeInsetsMake(5, 5, 5, 5);
}

点击这里查看苹果文档的UIEdgeInsetMake方法。

Swift 3版本

简单地创建一个UICollectionViewFlowLayout子类并粘贴这个方法。

override func layoutAttributesForElements(in rect: CGRect) -> [UICollectionViewLayoutAttributes]? {
        guard let answer = super.layoutAttributesForElements(in: rect) else { return nil }

        for i in 1..<answer.count {
            let currentAttributes = answer[i]
            let previousAttributes = answer[i - 1]

            let maximumSpacing: CGFloat = 8
            let origin = previousAttributes.frame.maxX

            if (origin + maximumSpacing + currentAttributes.frame.size.width < self.collectionViewContentSize.width && currentAttributes.frame.origin.x > previousAttributes.frame.origin.x) {
                var frame = currentAttributes.frame
                frame.origin.x = origin + maximumSpacing
                currentAttributes.frame = frame
            }
        }

        return answer
}

我使用monotouch，所以名称和代码会有点不同，但你可以通过确保集合视图的宽度等于(x *单元格宽度)+ (x-1) * MinimumSpacing与x =每行单元格的数量来做到这一点。

只需要根据MinimumInteritemSpacing和Cell的宽度执行以下步骤

1)我们根据单元格大小+当前插入+最小间距计算每行项目的数量

float currentTotalWidth = CollectionView.Frame.Width - Layout.SectionInset.Left - Layout.SectionInset.Right (Layout = flowlayout)
int amountOfCellsPerRow = (currentTotalWidth + MinimumSpacing) / (cell width + MinimumSpacing)

2)现在你有了所有信息来计算集合视图的预期宽度

float totalWidth =(amountOfCellsPerRow * cell width) + (amountOfCellsPerRow-1) * MinimumSpacing

3)所以当前宽度与预期宽度之差为

float difference = currentTotalWidth - totalWidth;

4)现在调整insets(在本例中，我们将其添加到右侧，因此集合视图的左侧位置保持不变

Layout.SectionInset.Right = Layout.SectionInset.Right + difference;

试试这个方法:

- (UIEdgeInsets)collectionView:(UICollectionView *)collectionView
                    layout:(UICollectionViewLayout*)collectionViewLayout
    insetForSectionAtIndex:(NSInteger)section {

    UIEdgeInsets insets = UIEdgeInsetsMake(?, ?, ?, ?);

    return insets;
}

投票的答案(以及快速版本)有一个小问题:右边会有一个很大的空格。

这是因为流布局是定制的，以使单元格间距精确，具有浮动左行为。

我的解决方案是操纵部分插入，使部分是对齐中心，但间距是完全指定的。

在下面的截图中，项目/行间距正好是8pt，而左右插入部分将大于8pt(使其居中对齐):

这样的Swift代码:

private let minItemSpacing: CGFloat = 8
private let itemWidth: CGFloat      = 100
private let headerHeight: CGFloat   = 32

override func viewDidLayoutSubviews() {
    super.viewDidLayoutSubviews()

    // Create our custom flow layout that evenly space out the items, and have them in the center
    let layout = UICollectionViewFlowLayout()
    layout.itemSize = CGSize(width: itemWidth, height: itemWidth)
    layout.minimumInteritemSpacing = minItemSpacing
    layout.minimumLineSpacing = minItemSpacing
    layout.headerReferenceSize = CGSize(width: 0, height: headerHeight)

    // Find n, where n is the number of item that can fit into the collection view
    var n: CGFloat = 1
    let containerWidth = collectionView.bounds.width
    while true {
        let nextN = n + 1
        let totalWidth = (nextN*itemWidth) + (nextN-1)*minItemSpacing
        if totalWidth > containerWidth {
            break
        } else {
            n = nextN
        }
    }

    // Calculate the section inset for left and right. 
    // Setting this section inset will manipulate the items such that they will all be aligned horizontally center.
    let inset = max(minItemSpacing, floor( (containerWidth - (n*itemWidth) - (n-1)*minItemSpacing) / 2 ) )
    layout.sectionInset = UIEdgeInsets(top: minItemSpacing, left: inset, bottom: minItemSpacing, right: inset)

    collectionView.collectionViewLayout = layout
}