我偶然发现了与op类似的问题。不幸的是，接受的答案不适合我，因为collectionView的内容不会正确居中。因此，我提出了一个不同的解决方案，只需要在collectionView中的所有项目都具有相同的宽度，这似乎是问题中的情况:

#define cellSize 90

- (UIEdgeInsets)collectionView:(UICollectionView *)collectionView layout:(UICollectionViewLayout *)collectionViewLayout insetForSectionAtIndex:(NSInteger)section {
    float width = collectionView.frame.size.width;
    float spacing = [self collectionView:collectionView layout:collectionViewLayout minimumInteritemSpacingForSectionAtIndex:section];
    int numberOfCells = (width + spacing) / (cellSize + spacing);
    int inset = (width + spacing - numberOfCells * (cellSize + spacing) ) / 2;

    return UIEdgeInsetsMake(0, inset, 0, inset);
}

该代码将确保…minimumInteritemSpacing…将是每个collectionViewCell之间的精确间距，并进一步保证所有的单元格一起将在collectionView

上面vojtech-vrbka的解决方案是正确的，但它会触发一个警告:

警告:UICollectionViewFlowLayout缓存的帧不匹配索引路径-缓存值:这可能是因为流布局子类layout是修改UICollectionViewFlowLayout返回的属性而没有复制它们

下面的代码应该修复它:

class CustomViewFlowLayout : UICollectionViewFlowLayout {

   let cellSpacing:CGFloat = 4

   override func layoutAttributesForElementsInRect(rect: CGRect) -> [UICollectionViewLayoutAttributes]? {
       let original = super.layoutAttributesForElementsInRect(rect)

       if let original = original {
           let attributes = NSArray.init(array: original, copyItems: true) as! [UICollectionViewLayoutAttributes]

           for (index, attribute) in attributes.enumerate() {
                if index == 0 { continue }
                let prevLayoutAttributes = attributes[index - 1]
                let origin = CGRectGetMaxX(prevLayoutAttributes.frame)
                if(origin + cellSpacing + attribute.frame.size.width < self.collectionViewContentSize().width) {
                    attribute.frame.origin.x = origin + cellSpacing
                }
            }
            return attributes
       }
       return nil
   }
}

投票的答案(以及快速版本)有一个小问题:右边会有一个很大的空格。

这是因为流布局是定制的，以使单元格间距精确，具有浮动左行为。

我的解决方案是操纵部分插入，使部分是对齐中心，但间距是完全指定的。

在下面的截图中，项目/行间距正好是8pt，而左右插入部分将大于8pt(使其居中对齐):

这样的Swift代码:

private let minItemSpacing: CGFloat = 8
private let itemWidth: CGFloat      = 100
private let headerHeight: CGFloat   = 32

override func viewDidLayoutSubviews() {
    super.viewDidLayoutSubviews()

    // Create our custom flow layout that evenly space out the items, and have them in the center
    let layout = UICollectionViewFlowLayout()
    layout.itemSize = CGSize(width: itemWidth, height: itemWidth)
    layout.minimumInteritemSpacing = minItemSpacing
    layout.minimumLineSpacing = minItemSpacing
    layout.headerReferenceSize = CGSize(width: 0, height: headerHeight)

    // Find n, where n is the number of item that can fit into the collection view
    var n: CGFloat = 1
    let containerWidth = collectionView.bounds.width
    while true {
        let nextN = n + 1
        let totalWidth = (nextN*itemWidth) + (nextN-1)*minItemSpacing
        if totalWidth > containerWidth {
            break
        } else {
            n = nextN
        }
    }

    // Calculate the section inset for left and right. 
    // Setting this section inset will manipulate the items such that they will all be aligned horizontally center.
    let inset = max(minItemSpacing, floor( (containerWidth - (n*itemWidth) - (n-1)*minItemSpacing) / 2 ) )
    layout.sectionInset = UIEdgeInsets(top: minItemSpacing, left: inset, bottom: minItemSpacing, right: inset)

    collectionView.collectionViewLayout = layout
}

间距的简单代码

let layout = collectionView.collectionViewLayout as! UICollectionViewFlowLayout
layout.minimumInteritemSpacing = 10 // Some float value

试试这个方法:

- (UIEdgeInsets)collectionView:(UICollectionView *)collectionView
                    layout:(UICollectionViewLayout*)collectionViewLayout
    insetForSectionAtIndex:(NSInteger)section {

    UIEdgeInsets insets = UIEdgeInsetsMake(?, ?, ?, ?);

    return insets;
}

我在Swift 3单元格间距的解决方案，如Instagram:

lazy var collectionView: UICollectionView = {
    let layout = UICollectionViewFlowLayout()
    let cv = UICollectionView(frame: .zero, collectionViewLayout: layout)
    cv.backgroundColor = UIColor.rgb(red: 227, green: 227, blue: 227)
    cv.showsVerticalScrollIndicator = false
    layout.scrollDirection = .vertical
    layout.minimumLineSpacing = 1
    layout.minimumInteritemSpacing = 1
    return cv
}()

func collectionView(_ collectionView: UICollectionView, layout collectionViewLayout: UICollectionViewLayout, sizeForItemAt indexPath: IndexPath) -> CGSize {

    switch UIDevice.current.modelName {
    case "iPhone 4":
        return CGSize(width: 106, height: 106)
    case "iPhone 5":
        return CGSize(width: 106, height: 106)
    case "iPhone 6,7":
        return CGSize(width: 124, height: 124)
    case "iPhone Plus":
        return CGSize(width: 137, height: 137)
    default:
        return CGSize(width: frame.width / 3, height: frame.width / 3)
    }
}

如何编程检测设备: https://stackoverflow.com/a/26962452/6013170