I once needed to upload PDFs to an online backup archive. But the backup would fail if the user had the file open in another program (such as PDF reader). In my haste, I attempted a few of the top answers in this thread but could not get them to work. What did work for me was trying to move the PDF file to its own directory. I found that this would fail if the file was open in another program, and if the move were successful there would be no restore-operation required as there would be if it were moved to a separate directory. I want to post my basic solution in case it may be useful for others' specific use cases.

string str_path_and_name = str_path + '\\' + str_filename;
FileInfo fInfo = new FileInfo(str_path_and_name);
bool open_elsewhere = false;
try
{
    fInfo.MoveTo(str_path_and_name);
}
catch (Exception ex)
{
    open_elsewhere = true;
}

if (open_elsewhere)
{
    //handle case
}

只要按预期使用异常即可。接受该文件正在使用，并再次尝试，直到操作完成。这也是最有效的，因为您不需要在执行之前浪费任何检查状态的周期。

例如，使用下面的函数

TimeoutFileAction(() => { System.IO.File.etc...; return null; } );

2秒后超时的可重用方法

private T TimeoutFileAction<T>(Func<T> func)
{
    var started = DateTime.UtcNow;
    while ((DateTime.UtcNow - started).TotalMilliseconds < 2000)
    {
        try
        {
            return func();                    
        }
        catch (System.IO.IOException exception)
        {
            //ignore, or log somewhere if you want to
        }
    }
    return default(T);
}

根据我的经验，你通常想这样做，然后“保护”你的文件做一些奇特的事情，然后使用“保护”文件。如果你只想这样使用一个文件，你可以使用Jeremy Thompson在回答中解释的技巧。但是，如果您试图对大量文件执行此操作(例如，当您正在编写安装程序时)，则会受到相当大的伤害。

解决这个问题的一个非常优雅的方法是，如果您的文件系统中有一个文件正在使用，那么它将不允许您更改文件夹名称。将文件夹保存在同一个文件系统中，它会非常有效。

请注意，您应该了解可以利用这一点的明显方式。毕竟，文件不会被锁定。此外，请注意还有其他原因可能导致Move操作失败。显然，适当的错误处理(MSDN)可以帮助解决这个问题。

var originalFolder = @"c:\myHugeCollectionOfFiles"; // your folder name here
var someFolder = Path.Combine(originalFolder, "..", Guid.NewGuid().ToString("N"));

try
{
    Directory.Move(originalFolder, someFolder);

    // Use files
}
catch // TODO: proper exception handling
{
    // Inform user, take action
}
finally
{
    Directory.Move(someFolder, originalFolder);
}

对于单个文件，我坚持使用Jeremy Thompson发布的锁定建议。

您可能会遇到线程竞争条件，有文档示例将此用作安全漏洞。如果您检查文件是否可用，但随后尝试使用它，则可能会在此时抛出，恶意用户可能会使用它来强制和利用您的代码。

最好的方法是try catch / finally，它尝试获取文件句柄。

try
{
   using (Stream stream = new FileStream("MyFilename.txt", FileMode.Open))
   {
        // File/Stream manipulating code here
   }
} catch {
  //check here why it failed and ask user to retry if the file is in use.
}

使用此命令检查文件是否被锁定:

using System.IO;
using System.Runtime.InteropServices;
internal static class Helper
{
const int ERROR_SHARING_VIOLATION = 32;
const int ERROR_LOCK_VIOLATION = 33;

private static bool IsFileLocked(Exception exception)
{
    int errorCode = Marshal.GetHRForException(exception) & ((1 << 16) - 1);
    return errorCode == ERROR_SHARING_VIOLATION || errorCode == ERROR_LOCK_VIOLATION;
}

internal static bool CanReadFile(string filePath)
{
    //Try-Catch so we dont crash the program and can check the exception
    try {
        //The "using" is important because FileStream implements IDisposable and
        //"using" will avoid a heap exhaustion situation when too many handles  
        //are left undisposed.
        using (FileStream fileStream = File.Open(filePath, FileMode.Open, FileAccess.ReadWrite, FileShare.None)) {
            if (fileStream != null) fileStream.Close();  //This line is me being overly cautious, fileStream will never be null unless an exception occurs... and I know the "using" does it but its helpful to be explicit - especially when we encounter errors - at least for me anyway!
        }
    }
    catch (IOException ex) {
        //THE FUNKY MAGIC - TO SEE IF THIS FILE REALLY IS LOCKED!!!
        if (IsFileLocked(ex)) {
            // do something, eg File.Copy or present the user with a MsgBox - I do not recommend Killing the process that is locking the file
            return false;
        }
    }
    finally
    { }
    return true;
}
}

出于性能考虑，我建议您在同一操作中读取文件内容。下面是一些例子:

public static byte[] ReadFileBytes(string filePath)
{
    byte[] buffer = null;
    try
    {
        using (FileStream fileStream = File.Open(filePath, FileMode.Open, FileAccess.ReadWrite, FileShare.None))
        {
            int length = (int)fileStream.Length;  // get file length
            buffer = new byte[length];            // create buffer
            int count;                            // actual number of bytes read
            int sum = 0;                          // total number of bytes read

            // read until Read method returns 0 (end of the stream has been reached)
            while ((count = fileStream.Read(buffer, sum, length - sum)) > 0)
                sum += count;  // sum is a buffer offset for next reading

            fileStream.Close(); //This is not needed, just me being paranoid and explicitly releasing resources ASAP
        }
    }
    catch (IOException ex)
    {
        //THE FUNKY MAGIC - TO SEE IF THIS FILE REALLY IS LOCKED!!!
        if (IsFileLocked(ex))
        {
            // do something? 
        }
    }
    catch (Exception ex)
    {
    }
    finally
    {
    }
    return buffer;
}

public static string ReadFileTextWithEncoding(string filePath)
{
    string fileContents = string.Empty;
    byte[] buffer;
    try
    {
        using (FileStream fileStream = File.Open(filePath, FileMode.Open, FileAccess.ReadWrite, FileShare.None))
        {
            int length = (int)fileStream.Length;  // get file length
            buffer = new byte[length];            // create buffer
            int count;                            // actual number of bytes read
            int sum = 0;                          // total number of bytes read

            // read until Read method returns 0 (end of the stream has been reached)
            while ((count = fileStream.Read(buffer, sum, length - sum)) > 0)
            {
                sum += count;  // sum is a buffer offset for next reading
            }

            fileStream.Close(); //Again - this is not needed, just me being paranoid and explicitly releasing resources ASAP

            //Depending on the encoding you wish to use - I'll leave that up to you
            fileContents = System.Text.Encoding.Default.GetString(buffer);
        }
    }
    catch (IOException ex)
    {
        //THE FUNKY MAGIC - TO SEE IF THIS FILE REALLY IS LOCKED!!!
        if (IsFileLocked(ex))
        {
            // do something? 
        }
    }
    catch (Exception ex)
    {
    }
    finally
    { }     
    return fileContents;
}

public static string ReadFileTextNoEncoding(string filePath)
{
    string fileContents = string.Empty;
    byte[] buffer;
    try
    {
        using (FileStream fileStream = File.Open(filePath, FileMode.Open, FileAccess.ReadWrite, FileShare.None))
        {
            int length = (int)fileStream.Length;  // get file length
            buffer = new byte[length];            // create buffer
            int count;                            // actual number of bytes read
            int sum = 0;                          // total number of bytes read

            // read until Read method returns 0 (end of the stream has been reached)
            while ((count = fileStream.Read(buffer, sum, length - sum)) > 0) 
            {
                sum += count;  // sum is a buffer offset for next reading
            }

            fileStream.Close(); //Again - this is not needed, just me being paranoid and explicitly releasing resources ASAP

            char[] chars = new char[buffer.Length / sizeof(char) + 1];
            System.Buffer.BlockCopy(buffer, 0, chars, 0, buffer.Length);
            fileContents = new string(chars);
        }
    }
    catch (IOException ex)
    {
        //THE FUNKY MAGIC - TO SEE IF THIS FILE REALLY IS LOCKED!!!
        if (IsFileLocked(ex))
        {
            // do something? 
        }
    }
    catch (Exception ex)
    {
    }
    finally
    {
    }

    return fileContents;
}

你自己试试吧:

byte[] output1 = Helper.ReadFileBytes(@"c:\temp\test.txt");
string output2 = Helper.ReadFileTextWithEncoding(@"c:\temp\test.txt");
string output3 = Helper.ReadFileTextNoEncoding(@"c:\temp\test.txt");

下面是一些代码，据我所知，它与接受的答案相同，但代码更少:

    public static bool IsFileLocked(string file)
    {
        try
        {
            using (var stream = File.OpenRead(file))
                return false;
        }
        catch (IOException)
        {
            return true;
        }        
    }

然而，我认为用以下方式来做会更稳健:

    public static void TryToDoWithFileStream(string file, Action<FileStream> action, 
        int count, int msecTimeOut)
    {
        FileStream stream = null;
        for (var i = 0; i < count; ++i)
        {
            try
            {
                stream = File.OpenRead(file);
                break;
            }
            catch (IOException)
            {
                Thread.Sleep(msecTimeOut);
            }
        }
        action(stream);
    }