static bool FileInUse(string path)
    {
        try
        {
            using (FileStream fs = new FileStream(path, FileMode.OpenOrCreate))
            {
                fs.CanWrite
            }
            return false;
        }
        catch (IOException ex)
        {
            return true;
        }
    }

string filePath = "C:\\Documents And Settings\\yourfilename";
bool isFileInUse;

isFileInUse = FileInUse(filePath);

// Then you can do some checking
if (isFileInUse)
   Console.WriteLine("File is in use");
else
   Console.WriteLine("File is not in use");

希望这能有所帮助!

上面接受的答案遇到了一个问题，如果文件已被打开以使用FileShare写入。读取模式或如果文件具有只读属性，代码将无法工作。这个修改后的解决方案最可靠，需要记住两件事(对于公认的解决方案也是如此):

它将不适用于已以写共享模式打开的文件 这没有考虑到线程问题，所以你需要锁定它或单独处理线程问题。

记住上面的内容，这将检查文件是被写入锁定还是被阻止读取锁定:

public static bool FileLocked(string FileName)
{
    FileStream fs = null;

    try
    {
        // NOTE: This doesn't handle situations where file is opened for writing by another process but put into write shared mode, it will not throw an exception and won't show it as write locked
        fs = File.Open(FileName, FileMode.Open, FileAccess.ReadWrite, FileShare.None); // If we can't open file for reading and writing then it's locked by another process for writing
    }
    catch (UnauthorizedAccessException) // https://msdn.microsoft.com/en-us/library/y973b725(v=vs.110).aspx
    {
        // This is because the file is Read-Only and we tried to open in ReadWrite mode, now try to open in Read only mode
        try
        {
            fs = File.Open(FileName, FileMode.Open, FileAccess.Read, FileShare.None);
        }
        catch (Exception)
        {
            return true; // This file has been locked, we can't even open it to read
        }
    }
    catch (Exception)
    {
        return true; // This file has been locked
    }
    finally
    {
        if (fs != null)
            fs.Close();
    }
    return false;
}

尝试将文件移动/复制到临时目录。如果可以的话，它没有锁，您可以安全地在临时目录中工作而不需要锁。否则就在x秒内再移动一次。

您可能会遇到线程竞争条件，有文档示例将此用作安全漏洞。如果您检查文件是否可用，但随后尝试使用它，则可能会在此时抛出，恶意用户可能会使用它来强制和利用您的代码。

最好的方法是try catch / finally，它尝试获取文件句柄。

try
{
   using (Stream stream = new FileStream("MyFilename.txt", FileMode.Open))
   {
        // File/Stream manipulating code here
   }
} catch {
  //check here why it failed and ask user to retry if the file is in use.
}

也许您可以使用FileSystemWatcher并观察“已更改”事件。

我自己还没用过这个，但也许值得一试。如果对于这种情况，文件系统监控器显得有点重，那么我将使用try/catch/sleep循环。

只要按预期使用异常即可。接受该文件正在使用，并再次尝试，直到操作完成。这也是最有效的，因为您不需要在执行之前浪费任何检查状态的周期。

例如，使用下面的函数

TimeoutFileAction(() => { System.IO.File.etc...; return null; } );

2秒后超时的可重用方法

private T TimeoutFileAction<T>(Func<T> func)
{
    var started = DateTime.UtcNow;
    while ((DateTime.UtcNow - started).TotalMilliseconds < 2000)
    {
        try
        {
            return func();                    
        }
        catch (System.IO.IOException exception)
        {
            //ignore, or log somewhere if you want to
        }
    }
    return default(T);
}