我编写了测试来比较几种JavaScript哈希实现，包括这里提到的大多数MD5实现。 要运行测试，请访问http://brillout.github.io/test-javascript-hash-implementations/并稍等片刻。

似乎R. Hill的答案的YaMD5实现是最快的。

在选择库时，也要看它是否支持现代框架(如Bower)，是否通过jslint，是否支持JQuery插件模型或模块系统(如AMD/RequireJS)，以及是否正在积极开发中，是否有超过1个贡献者。有几个选项可以满足这些附加条件的一部分或全部:

CryptoJS: This is perhaps the most expansive library where each algorithm can be used separately without adding fat in to your JS code. Plus it as encoder/decoders for UTF8, UTF16 and Base64. I maintain github repository that is registered as Bower package plus instructions on how to use it with RequireJS. Spark MD5: This is based on JKM code that other answer mentions which is also the faster implementation. However in addition, Spark implementation adds AMD support, passes jslint plus has incremental mode. It doesn't have Base64 o/p but it does have raw o/p (i.e. array of 32-bit int insead of string). JQuery MD5 plugin: Very simple down to earth but doesn't seem to have raw mode. JavaScript-MD5: Not as fancy or fast as Spark but simpler.

来自CryptoJS的例子:

//just include md5.js from the CryptoJS rollups folder
var hash = CryptoJS.MD5("Message");
console.log(hash.toString()); 

在http://jsperf.com/md5-shootout/7上有上述库之间的性能比较。在我的机器上，当前的测试(不可否认是旧的)表明，如果您正在寻找速度，Spark MD5是您的最佳选择(普通JKM代码也是如此)。然而，如果你正在寻找更全面的库，那么CryptoJS是你最好的选择，尽管它比Spark MD5慢79%。然而，我想CryptoJS最终会达到同样的速度，因为它是一个更活跃的项目。

我找到了许多关于这个主题的文章。 他们都建议约瑟夫·迈耶斯实施。

在某些测试中，请参阅:http://jsperf.com/md5-shootout

在我对终极速度的追求中，我看了这段代码，我看到它可以改进。所以我基于Joseph Meyers代码创建了一个新的JS脚本。

参见改进的约瑟夫迈耶斯代码

我最喜欢的md5

这篇文章有42行长，横向可容纳120个字符，看起来不错。它快吗?好吧，它足够快了，它和所有其他JS实现差不多。但看着这些排列整齐的列，会有一种奇怪的满足感。不否认。

//  A formatted version of a popular md5 implementation.
//  Original copyright (c) Paul Johnston & Greg Holt.
//  The function itself is now 42 lines long.

function md5(inputString) {
    var hc="0123456789abcdef";
    function rh(n) {var j,s="";for(j=0;j<=3;j++) s+=hc.charAt((n>>(j*8+4))&0x0F)+hc.charAt((n>>(j*8))&0x0F);return s;}
    function ad(x,y) {var l=(x&0xFFFF)+(y&0xFFFF);var m=(x>>16)+(y>>16)+(l>>16);return (m<<16)|(l&0xFFFF);}
    function rl(n,c)            {return (n<<c)|(n>>>(32-c));}
    function cm(q,a,b,x,s,t)    {return ad(rl(ad(ad(a,q),ad(x,t)),s),b);}
    function ff(a,b,c,d,x,s,t)  {return cm((b&c)|((~b)&d),a,b,x,s,t);}
    function gg(a,b,c,d,x,s,t)  {return cm((b&d)|(c&(~d)),a,b,x,s,t);}
    function hh(a,b,c,d,x,s,t)  {return cm(b^c^d,a,b,x,s,t);}
    function ii(a,b,c,d,x,s,t)  {return cm(c^(b|(~d)),a,b,x,s,t);}
    function sb(x) {
        var i;var nblk=((x.length+8)>>6)+1;var blks=new Array(nblk*16);for(i=0;i<nblk*16;i++) blks[i]=0;
        for(i=0;i<x.length;i++) blks[i>>2]|=x.charCodeAt(i)<<((i%4)*8);
        blks[i>>2]|=0x80<<((i%4)*8);blks[nblk*16-2]=x.length*8;return blks;
    }
    var i,x=sb(inputString),a=1732584193,b=-271733879,c=-1732584194,d=271733878,olda,oldb,oldc,oldd;
    for(i=0;i<x.length;i+=16) {olda=a;oldb=b;oldc=c;oldd=d;
        a=ff(a,b,c,d,x[i+ 0], 7, -680876936);d=ff(d,a,b,c,x[i+ 1],12, -389564586);c=ff(c,d,a,b,x[i+ 2],17,  606105819);
        b=ff(b,c,d,a,x[i+ 3],22,-1044525330);a=ff(a,b,c,d,x[i+ 4], 7, -176418897);d=ff(d,a,b,c,x[i+ 5],12, 1200080426);
        c=ff(c,d,a,b,x[i+ 6],17,-1473231341);b=ff(b,c,d,a,x[i+ 7],22,  -45705983);a=ff(a,b,c,d,x[i+ 8], 7, 1770035416);
        d=ff(d,a,b,c,x[i+ 9],12,-1958414417);c=ff(c,d,a,b,x[i+10],17,     -42063);b=ff(b,c,d,a,x[i+11],22,-1990404162);
        a=ff(a,b,c,d,x[i+12], 7, 1804603682);d=ff(d,a,b,c,x[i+13],12,  -40341101);c=ff(c,d,a,b,x[i+14],17,-1502002290);
        b=ff(b,c,d,a,x[i+15],22, 1236535329);a=gg(a,b,c,d,x[i+ 1], 5, -165796510);d=gg(d,a,b,c,x[i+ 6], 9,-1069501632);
        c=gg(c,d,a,b,x[i+11],14,  643717713);b=gg(b,c,d,a,x[i+ 0],20, -373897302);a=gg(a,b,c,d,x[i+ 5], 5, -701558691);
        d=gg(d,a,b,c,x[i+10], 9,   38016083);c=gg(c,d,a,b,x[i+15],14, -660478335);b=gg(b,c,d,a,x[i+ 4],20, -405537848);
        a=gg(a,b,c,d,x[i+ 9], 5,  568446438);d=gg(d,a,b,c,x[i+14], 9,-1019803690);c=gg(c,d,a,b,x[i+ 3],14, -187363961);
        b=gg(b,c,d,a,x[i+ 8],20, 1163531501);a=gg(a,b,c,d,x[i+13], 5,-1444681467);d=gg(d,a,b,c,x[i+ 2], 9,  -51403784);
        c=gg(c,d,a,b,x[i+ 7],14, 1735328473);b=gg(b,c,d,a,x[i+12],20,-1926607734);a=hh(a,b,c,d,x[i+ 5], 4,    -378558);
        d=hh(d,a,b,c,x[i+ 8],11,-2022574463);c=hh(c,d,a,b,x[i+11],16, 1839030562);b=hh(b,c,d,a,x[i+14],23,  -35309556);
        a=hh(a,b,c,d,x[i+ 1], 4,-1530992060);d=hh(d,a,b,c,x[i+ 4],11, 1272893353);c=hh(c,d,a,b,x[i+ 7],16, -155497632);
        b=hh(b,c,d,a,x[i+10],23,-1094730640);a=hh(a,b,c,d,x[i+13], 4,  681279174);d=hh(d,a,b,c,x[i+ 0],11, -358537222);
        c=hh(c,d,a,b,x[i+ 3],16, -722521979);b=hh(b,c,d,a,x[i+ 6],23,   76029189);a=hh(a,b,c,d,x[i+ 9], 4, -640364487);
        d=hh(d,a,b,c,x[i+12],11, -421815835);c=hh(c,d,a,b,x[i+15],16,  530742520);b=hh(b,c,d,a,x[i+ 2],23, -995338651);
        a=ii(a,b,c,d,x[i+ 0], 6, -198630844);d=ii(d,a,b,c,x[i+ 7],10, 1126891415);c=ii(c,d,a,b,x[i+14],15,-1416354905);
        b=ii(b,c,d,a,x[i+ 5],21,  -57434055);a=ii(a,b,c,d,x[i+12], 6, 1700485571);d=ii(d,a,b,c,x[i+ 3],10,-1894986606);
        c=ii(c,d,a,b,x[i+10],15,   -1051523);b=ii(b,c,d,a,x[i+ 1],21,-2054922799);a=ii(a,b,c,d,x[i+ 8], 6, 1873313359);
        d=ii(d,a,b,c,x[i+15],10,  -30611744);c=ii(c,d,a,b,x[i+ 6],15,-1560198380);b=ii(b,c,d,a,x[i+13],21, 1309151649);
        a=ii(a,b,c,d,x[i+ 4], 6, -145523070);d=ii(d,a,b,c,x[i+11],10,-1120210379);c=ii(c,d,a,b,x[i+ 2],15,  718787259);
        b=ii(b,c,d,a,x[i+ 9],21, -343485551);a=ad(a,olda);b=ad(b,oldb);c=ad(c,oldc);d=ad(d,oldd);
    }
    return rh(a)+rh(b)+rh(c)+rh(d);
}

另一个完全无关的事实是:它有4000字节长。这似乎毫无意义，但知道就感觉很好。你看着它，你知道。你是秘密俱乐部的一员。生活将从此不同。相信我。

同时，感谢保罗·约翰斯顿和格雷格·霍尔特。 还有道格拉斯·亚当斯，所有的鱼。

Stackblitz试样

您还可以检查我的md5实现。应该是大约。和上面其他贴的一样。不幸的是，性能受到内环的限制，不可能进一步优化。

下面是@dkellner和@Eonasdan的md5实现的ES6版本:

const md5 = inputString => {
   const hc = '0123456789abcdef';
   const rh = n => {let j,s='';for(j=0;j<=3;j++) s+=hc.charAt((n>>(j*8+4))&0x0F)+hc.charAt((n>>(j*8))&0x0F);return s;}
   const ad = (x,y) => {let l=(x&0xFFFF)+(y&0xFFFF);let m=(x>>16)+(y>>16)+(l>>16);return (m<<16)|(l&0xFFFF);}
   const rl = (n,c) => (n<<c)|(n>>>(32-c));
   const cm = (q,a,b,x,s,t) => ad(rl(ad(ad(a,q),ad(x,t)),s),b);
   const ff = (a,b,c,d,x,s,t) => cm((b&c)|((~b)&d),a,b,x,s,t);
   const gg = (a,b,c,d,x,s,t) => cm((b&d)|(c&(~d)),a,b,x,s,t);
   const hh = (a,b,c,d,x,s,t) => cm(b^c^d,a,b,x,s,t);
   const ii = (a,b,c,d,x,s,t) => cm(c^(b|(~d)),a,b,x,s,t);
   const sb = x => {
      let i;const nblk=((x.length+8)>>6)+1;const blks=[];for(i=0;i<nblk*16;i++) { blks[i]=0 };
      for(i=0;i<x.length;i++) {blks[i>>2]|=x.charCodeAt(i)<<((i%4)*8);}
      blks[i>>2]|=0x80<<((i%4)*8);blks[nblk*16-2]=x.length*8;return blks;
   }
   let i,x=sb(inputString),a=1732584193,b=-271733879,c=-1732584194,d=271733878,olda,oldb,oldc,oldd;
   for(i=0;i<x.length;i+=16) {olda=a;oldb=b;oldc=c;oldd=d;
      a=ff(a,b,c,d,x[i+ 0], 7, -680876936);d=ff(d,a,b,c,x[i+ 1],12, -389564586);c=ff(c,d,a,b,x[i+ 2],17,  606105819);
      b=ff(b,c,d,a,x[i+ 3],22,-1044525330);a=ff(a,b,c,d,x[i+ 4], 7, -176418897);d=ff(d,a,b,c,x[i+ 5],12, 1200080426);
      c=ff(c,d,a,b,x[i+ 6],17,-1473231341);b=ff(b,c,d,a,x[i+ 7],22,  -45705983);a=ff(a,b,c,d,x[i+ 8], 7, 1770035416);
      d=ff(d,a,b,c,x[i+ 9],12,-1958414417);c=ff(c,d,a,b,x[i+10],17,     -42063);b=ff(b,c,d,a,x[i+11],22,-1990404162);
      a=ff(a,b,c,d,x[i+12], 7, 1804603682);d=ff(d,a,b,c,x[i+13],12,  -40341101);c=ff(c,d,a,b,x[i+14],17,-1502002290);
      b=ff(b,c,d,a,x[i+15],22, 1236535329);a=gg(a,b,c,d,x[i+ 1], 5, -165796510);d=gg(d,a,b,c,x[i+ 6], 9,-1069501632);
      c=gg(c,d,a,b,x[i+11],14,  643717713);b=gg(b,c,d,a,x[i+ 0],20, -373897302);a=gg(a,b,c,d,x[i+ 5], 5, -701558691);
      d=gg(d,a,b,c,x[i+10], 9,   38016083);c=gg(c,d,a,b,x[i+15],14, -660478335);b=gg(b,c,d,a,x[i+ 4],20, -405537848);
      a=gg(a,b,c,d,x[i+ 9], 5,  568446438);d=gg(d,a,b,c,x[i+14], 9,-1019803690);c=gg(c,d,a,b,x[i+ 3],14, -187363961);
      b=gg(b,c,d,a,x[i+ 8],20, 1163531501);a=gg(a,b,c,d,x[i+13], 5,-1444681467);d=gg(d,a,b,c,x[i+ 2], 9,  -51403784);
      c=gg(c,d,a,b,x[i+ 7],14, 1735328473);b=gg(b,c,d,a,x[i+12],20,-1926607734);a=hh(a,b,c,d,x[i+ 5], 4,    -378558);
      d=hh(d,a,b,c,x[i+ 8],11,-2022574463);c=hh(c,d,a,b,x[i+11],16, 1839030562);b=hh(b,c,d,a,x[i+14],23,  -35309556);
      a=hh(a,b,c,d,x[i+ 1], 4,-1530992060);d=hh(d,a,b,c,x[i+ 4],11, 1272893353);c=hh(c,d,a,b,x[i+ 7],16, -155497632);
      b=hh(b,c,d,a,x[i+10],23,-1094730640);a=hh(a,b,c,d,x[i+13], 4,  681279174);d=hh(d,a,b,c,x[i+ 0],11, -358537222);
      c=hh(c,d,a,b,x[i+ 3],16, -722521979);b=hh(b,c,d,a,x[i+ 6],23,   76029189);a=hh(a,b,c,d,x[i+ 9], 4, -640364487);
      d=hh(d,a,b,c,x[i+12],11, -421815835);c=hh(c,d,a,b,x[i+15],16,  530742520);b=hh(b,c,d,a,x[i+ 2],23, -995338651);
      a=ii(a,b,c,d,x[i+ 0], 6, -198630844);d=ii(d,a,b,c,x[i+ 7],10, 1126891415);c=ii(c,d,a,b,x[i+14],15,-1416354905);
      b=ii(b,c,d,a,x[i+ 5],21,  -57434055);a=ii(a,b,c,d,x[i+12], 6, 1700485571);d=ii(d,a,b,c,x[i+ 3],10,-1894986606);
      c=ii(c,d,a,b,x[i+10],15,   -1051523);b=ii(b,c,d,a,x[i+ 1],21,-2054922799);a=ii(a,b,c,d,x[i+ 8], 6, 1873313359);
      d=ii(d,a,b,c,x[i+15],10,  -30611744);c=ii(c,d,a,b,x[i+ 6],15,-1560198380);b=ii(b,c,d,a,x[i+13],21, 1309151649);
      a=ii(a,b,c,d,x[i+ 4], 6, -145523070);d=ii(d,a,b,c,x[i+11],10,-1120210379);c=ii(c,d,a,b,x[i+ 2],15,  718787259);
      b=ii(b,c,d,a,x[i+ 9],21, -343485551);a=ad(a,olda);b=ad(b,oldb);c=ad(c,oldc);d=ad(d,oldd);
   }
   return rh(a)+rh(b)+rh(c)+rh(d);
}