微软为此提供了一个代码示例:

http://1code.codeplex.com/SourceControl/changeset/view/39074#842775

它是这样的:

    /// <summary>
    /// The function determines whether the current operating system is a 
    /// 64-bit operating system.
    /// </summary>
    /// <returns>
    /// The function returns true if the operating system is 64-bit; 
    /// otherwise, it returns false.
    /// </returns>
    public static bool Is64BitOperatingSystem()
    {
        if (IntPtr.Size == 8)  // 64-bit programs run only on Win64
        {
            return true;
        }
        else  // 32-bit programs run on both 32-bit and 64-bit Windows
        {
            // Detect whether the current process is a 32-bit process 
            // running on a 64-bit system.
            bool flag;
            return ((DoesWin32MethodExist("kernel32.dll", "IsWow64Process") &&
                IsWow64Process(GetCurrentProcess(), out flag)) && flag);
        }
    }

    /// <summary>
    /// The function determins whether a method exists in the export 
    /// table of a certain module.
    /// </summary>
    /// <param name="moduleName">The name of the module</param>
    /// <param name="methodName">The name of the method</param>
    /// <returns>
    /// The function returns true if the method specified by methodName 
    /// exists in the export table of the module specified by moduleName.
    /// </returns>
    static bool DoesWin32MethodExist(string moduleName, string methodName)
    {
        IntPtr moduleHandle = GetModuleHandle(moduleName);
        if (moduleHandle == IntPtr.Zero)
        {
            return false;
        }
        return (GetProcAddress(moduleHandle, methodName) != IntPtr.Zero);
    }

    [DllImport("kernel32.dll")]
    static extern IntPtr GetCurrentProcess();

    [DllImport("kernel32.dll", CharSet = CharSet.Auto)]
    static extern IntPtr GetModuleHandle(string moduleName);

    [DllImport("kernel32", CharSet = CharSet.Auto, SetLastError = true)]
    static extern IntPtr GetProcAddress(IntPtr hModule,
        [MarshalAs(UnmanagedType.LPStr)]string procName);

    [DllImport("kernel32.dll", CharSet = CharSet.Auto, SetLastError = true)]
    [return: MarshalAs(UnmanagedType.Bool)]
    static extern bool IsWow64Process(IntPtr hProcess, out bool wow64Process);

还有一个可用的WMI版本(用于测试远程机器)。

一切都很好，但这也应该在env中工作:

PROCESSOR_ARCHITECTURE=x86

..

PROCESSOR_ARCHITECTURE=AMD64

可能太简单了;-)

. net 4在环境类中有两个新属性，Is64BitProcess和Is64BitOperatingSystem。有趣的是，如果你使用Reflector，你会发现它们在32位和64位版本的mscorlib中实现的不同。32位版本为Is64BitProcess返回false，并通过P/Invoke为Is64BitOperatingSystem调用IsWow64Process。64位版本对两者都返回true。

对不起，是VB的代码。NET，但是很容易移植到c#。 它可以在Win7, x64和.Net Framework 4.8上正常工作:

Dim r As String = ""
Using searcher As ManagementObjectSearcher = New System.Management.ManagementObjectSearcher("SELECT * FROM Win32_OperatingSystem")
    Dim Information As ManagementObjectCollection = searcher.Get()
    If Information IsNot Nothing Then
        For Each obj As ManagementObject In Information
            r = obj("Caption").ToString() & _
            " - " & _
            obj("OSArchitecture").ToString() ' <--- !!! "64-bit" shown here
        Next
    End If
    MessageBox.Show(r)
End Using

在你的项目中包含以下代码:

    [DllImport("kernel32.dll", SetLastError = true, CallingConvention = CallingConvention.Winapi)]
    [return: MarshalAs(UnmanagedType.Bool)]
    private static extern bool IsWow64Process([In] IntPtr hProcess, [Out] out bool wow64Process);

    public static int GetBit()
    {
        int MethodResult = "";
        try
        {
            int Architecture = 32;

            if ((Environment.OSVersion.Version.Major == 5 && Environment.OSVersion.Version.Minor >= 1) || Environment.OSVersion.Version.Major >= 6)
            {
                using (Process p = Process.GetCurrentProcess())
                {
                    bool Is64Bit;

                    if (IsWow64Process(p.Handle, out Is64Bit))
                    {
                        if (Is64Bit)
                        {
                            Architecture = 64;

                        }

                    }

                }

            }

            MethodResult = Architecture;

        }
        catch //(Exception ex)
        {
            //ex.HandleException();
        }
        return MethodResult;
    }

像这样使用它:

string Architecture = "This is a " + GetBit() + "bit machine";

这只是Bruno Lopez上面建议的一个实现，但适用于Win2k +所有的WinXP服务包。我只是想把它贴出来这样别人就不用亲手卷了。(本可以作为评论发布，但我是一个新用户!)

[DllImport("kernel32", SetLastError = true, CallingConvention = CallingConvention.Winapi)]
public extern static IntPtr LoadLibrary(string libraryName);

[DllImport("kernel32", SetLastError = true, CallingConvention = CallingConvention.Winapi)]
public extern static IntPtr GetProcAddress(IntPtr hwnd, string procedureName);

private delegate bool IsWow64ProcessDelegate([In] IntPtr handle, [Out] out bool isWow64Process);

public static bool IsOS64Bit()
{
    if (IntPtr.Size == 8 || (IntPtr.Size == 4 && Is32BitProcessOn64BitProcessor()))
    {
        return true;
    }
    else
    {
        return false;
    }
}

private static IsWow64ProcessDelegate GetIsWow64ProcessDelegate()
{
  IntPtr handle = LoadLibrary("kernel32");

  if ( handle != IntPtr.Zero)
  {
    IntPtr fnPtr = GetProcAddress(handle, "IsWow64Process");

    if (fnPtr != IntPtr.Zero)
    {
      return (IsWow64ProcessDelegate)Marshal.GetDelegateForFunctionPointer((IntPtr)fnPtr, typeof(IsWow64ProcessDelegate));
    }
  }

  return null;
}

private static bool Is32BitProcessOn64BitProcessor()
{
  IsWow64ProcessDelegate fnDelegate = GetIsWow64ProcessDelegate();

  if (fnDelegate == null)
  {
    return false;
  }

  bool isWow64;
  bool retVal = fnDelegate.Invoke(Process.GetCurrentProcess().Handle, out isWow64);

  if (retVal == false)
  {
    return false;
  }

  return isWow64;
}