它适用于我和灵活的内容和文件

public static String getMimeType(Context context, Uri uri) {
    String extension;

    //Check uri format to avoid null
    if (uri.getScheme().equals(ContentResolver.SCHEME_CONTENT)) {
        //If scheme is a content
        final MimeTypeMap mime = MimeTypeMap.getSingleton();
        extension = mime.getExtensionFromMimeType(context.getContentResolver().getType(uri));
    } else {
        //If scheme is a File
        //This will replace white spaces with %20 and also other special characters. This will avoid returning null values on file name with spaces and special characters.
        extension = MimeTypeMap.getFileExtensionFromUrl(Uri.fromFile(new File(uri.getPath())).toString());

    }

    return extension;
}

get file object....
File file = new File(filePath);

then....pass as a parameter to...

getMimeType(file);

...here is 


public String getMimeType(File file) {
        String mimetype = MimeTypeMap.getSingleton().getMimeTypeFromExtension(MimeTypeMap.getFileExtensionFromUrl(Uri.fromFile(file).toString()).toLowerCase());
        if (mimetype == null) {
            return "*/*";
        }
        return mimetype;///return the mimeType
    }

这里没有一个答案是完美的。以下是一个结合了所有热门答案的最佳元素的答案:

public final class FileUtil {

    // By default, Android doesn't provide support for JSON
    public static final String MIME_TYPE_JSON = "application/json";

    @Nullable
    public static String getMimeType(@NonNull Context context, @NonNull Uri uri) {

        String mimeType = null;
        if (uri.getScheme().equals(ContentResolver.SCHEME_CONTENT)) {
            ContentResolver cr = context.getContentResolver();
            mimeType = cr.getType(uri);
        } else {
            String fileExtension = getExtension(uri.toString());

            if(fileExtension == null){
                return null;
            }

            mimeType = MimeTypeMap.getSingleton().getMimeTypeFromExtension(
                    fileExtension.toLowerCase());

            if(mimeType == null){
                // Handle the misc file extensions
                return handleMiscFileExtensions(fileExtension);
            }
        }
        return mimeType;
    }

    @Nullable
    private static String getExtension(@Nullable String fileName){

        if(fileName == null || TextUtils.isEmpty(fileName)){
            return null;
        }

        char[] arrayOfFilename = fileName.toCharArray();
        for(int i = arrayOfFilename.length-1; i > 0; i--){
            if(arrayOfFilename[i] == '.'){
                return fileName.substring(i+1, fileName.length());
            }
        }
        return null;
    }

    @Nullable
    private static String handleMiscFileExtensions(@NonNull String extension){

        if(extension.equals("json")){
            return MIME_TYPE_JSON;
        }
        else{
            return null;
        }
    }
}

Jens的回答的优化版本与零安全和回退类型。

@NonNull
static String getMimeType(@NonNull File file) {
    String type = null;
    final String url = file.toString();
    final String extension = MimeTypeMap.getFileExtensionFromUrl(url);
    if (extension != null) {
        type = MimeTypeMap.getSingleton().getMimeTypeFromExtension(extension.toLowerCase());
    }
    if (type == null) {
        type = "image/*"; // fallback type. You might set it to */*
    }
    return type;
}

重要:getFileExtensionFromUrl()只适用于小写字母!

更新(19.03.2018)

好处:上面的方法是一个不那么冗长的Kotlin扩展函数:

fun File.getMimeType(fallback: String = "image/*"): String {
    return MimeTypeMap.getFileExtensionFromUrl(toString())
            ?.run { MimeTypeMap.getSingleton().getMimeTypeFromExtension(toLowerCase()) }
            ?: fallback // You might set it to */*
}

而从资产/文件(注意，在MimeTypeMap中缺少一些情况)。

private String getMimeType(String path) {
    if (null == path) return "*/*";

    String extension = path;
    int lastDot = extension.lastIndexOf('.');
    if (lastDot != -1) {
        extension = extension.substring(lastDot + 1);
    }

    // Convert the URI string to lower case to ensure compatibility with MimeTypeMap (see CB-2185).
    extension = extension.toLowerCase(Locale.getDefault());
    if (extension.equals("3ga")) {
        return "audio/3gpp";
    } else if (extension.equals("js")) {
        return "text/javascript";
    } else if (extension.equals("woff")) {
        return "application/x-font-woff";
    } else {
        // TODO
        // anyting missing from the map (http://www.sitepoint.com/web-foundations/mime-types-complete-list/)
        // reference: http://grepcode.com/file/repo1.maven.org/maven2/com.google.okhttp/okhttp/20120626/libcore/net/MimeUtils.java#MimeUtils
    }

    return MimeTypeMap.getSingleton().getMimeTypeFromExtension(extension);
}

而使用ContentResolver

contentResolver.getType(uri)

当http/https请求

    try {
        HttpURLConnection conn = httpClient.open(new URL(uri.toString()));
        conn.setDoInput(false);
        conn.setRequestMethod("HEAD");
        return conn.getHeaderField("Content-Type");
    } catch (IOException e) {
    }

上面的解决方案在.rar文件的情况下返回null，使用URLConnection.guessContentTypeFromName(url)在这种情况下工作。