string ToBeReplaceCharacters = @"~()@#$%&+,'"<>|;\/*?";
string fileName = "filename;with<bad:separators?";

foreach (var RepChar in ToBeReplaceCharacters)
{
    fileName = fileName.Replace(RepChar.ToString(), "");
}

就性能而言，这可能不是最好的解决方案，但它确实有效。

var str = "filename:with&bad$separators.txt";
char[] charArray = new char[] { '#', '%', '&', '{', '}', '\\', '<', '>', '*', '?', '/', ' ', '$', '!', '\'', '"', ':', '@' };
foreach (var singleChar in charArray)
{
   str = str.Replace(singleChar, '_');
}

如果你觉得自己特别聪明，不想使用Regex:

char[] separators = new char[]{' ',';',',','\r','\t','\n'};

string s = "this;is,\ra\t\n\n\ntest";
string[] temp = s.Split(separators, StringSplitOptions.RemoveEmptyEntries);
s = String.Join("\n", temp);

您也可以用一个扩展方法来包装它。

编辑:或者只要等2分钟，我还是会把它写完:)

public static class ExtensionMethods
{
   public static string Replace(this string s, char[] separators, string newVal)
   {
       string[] temp;

       temp = s.Split(separators, StringSplitOptions.RemoveEmptyEntries);
       return String.Join( newVal, temp );
   }
}

和瞧...

char[] separators = new char[]{' ',';',',','\r','\t','\n'};
string s = "this;is,\ra\t\n\n\ntest";

s = s.Replace(separators, "\n");

哦，表演太恐怖了! 答案有点过时了，但仍然……

public static class StringUtils
{
    #region Private members

    [ThreadStatic]
    private static StringBuilder m_ReplaceSB;

    private static StringBuilder GetReplaceSB(int capacity)
    {
        var result = m_ReplaceSB;

        if (null == result)
        {
            result = new StringBuilder(capacity);
            m_ReplaceSB = result;
        }
        else
        {
            result.Clear();
            result.EnsureCapacity(capacity);
        }

        return result;
    }


    public static string ReplaceAny(this string s, char replaceWith, params char[] chars)
    {
        if (null == chars)
            return s;

        if (null == s)
            return null;

        StringBuilder sb = null;

        for (int i = 0, count = s.Length; i < count; i++)
        {
            var temp = s[i];
            var replace = false;

            for (int j = 0, cc = chars.Length; j < cc; j++)
                if (temp == chars[j])
                {
                    if (null == sb)
                    {
                        sb = GetReplaceSB(count);
                        if (i > 0)
                            sb.Append(s, 0, i);
                    }

                    replace = true;
                    break;
                }

            if (replace)
                sb.Append(replaceWith);
            else
                if (null != sb)
                    sb.Append(temp);
        }

        return null == sb ? s : sb.ToString();
    }
}

没有“替换”(仅限Linq):

    string myString = ";,\r\t \n\n=1;;2,,3\r\r4\t\t5  6\n\n\n\n7=";
    char NoRepeat = '\n';
    string ByeBye = ";,\r\t ";
    string myResult = myString.ToCharArray().Where(t => !"STOP-OUTSIDER".Contains(t))
                 .Select(t => "" + ( ByeBye.Contains(t) ? '\n' : t))
                  .Aggregate((all, next) => (
                      next == "" + NoRepeat && all.Substring(all.Length - 1) == "" + NoRepeat
                      ? all : all  + next ) );

我也摆弄了一下这个问题，发现这里的大多数解决方案都非常缓慢。最快的方法实际上是dodgy_coder发布的LINQ + Aggregate方法。

但我想，这也可能是相当沉重的内存分配取决于有多少旧字符。所以我得出了这个结论:

这里的想法是为当前线程缓存旧字符的替换映射，以实现安全分配。除此之外，只是处理输入的字符数组之后会再次以字符串的形式返回。而字符数组则被尽可能少地修改。

[ThreadStatic]
private static bool[] replaceMap;
public static string Replace(this string input, char[] oldChars, char newChar)
{
    if (input == null) throw new ArgumentNullException(nameof(input));
    if (oldChars == null) throw new ArgumentNullException(nameof(oldChars));
    if (oldChars.Length == 1) return input.Replace(oldChars[0], newChar);
    if (oldChars.Length == 0) return input;

    replaceMap = replaceMap ?? new bool[char.MaxValue + 1];
    foreach (var oldChar in oldChars)
    {
        replaceMap[oldChar] = true;
    }

    try
    {
        var count = input.Length;
        var output = input.ToCharArray();
        for (var i = 0; i < count; i++)
        {
            if (replaceMap[input[i]])
            {
                output[i] = newChar;
            }
        }

        return new string(output);
    }
    finally
    {
        foreach (var oldChar in oldChars)
        {
            replaceMap[oldChar] = false;
        }
    }
}

对我来说，对于实际的输入字符串，这最多是两个分配。由于某些原因，StringBuilder对我来说要慢得多。它比LINQ变体快2倍。