// Create a request variable and assign a new XMLHttpRequest object to it.
var request = new XMLHttpRequest()

// Open a new connection, using the GET request on the URL endpoint
request.open('GET', 'restUrl', true)

request.onload = function () {
  // Begin accessing JSON data here
}

// Send request
request.send()

<button type="button" onclick="loadXMLDoc()"> GET CONTENT</button>

 <script>
        function loadXMLDoc() {
            var xmlhttp = new XMLHttpRequest();
            var url = "<Enter URL>";``
            xmlhttp.onload = function () {
                if (xmlhttp.readyState == 4 && xmlhttp.status == "200") {
                    document.getElementById("demo").innerHTML = this.responseText;
                }
            }
            xmlhttp.open("GET", url, true);
            xmlhttp.send();
        }
    </script>

对于那些使用AngularJs的人来说，它是$http.get:

$http.get('/someUrl').
  success(function(data, status, headers, config) {
    // this callback will be called asynchronously
    // when the response is available
  }).
  error(function(data, status, headers, config) {
    // called asynchronously if an error occurs
    // or server returns response with an error status.
  });

// Create a request variable and assign a new XMLHttpRequest object to it.
var request = new XMLHttpRequest()

// Open a new connection, using the GET request on the URL endpoint
request.open('GET', 'restUrl', true)

request.onload = function () {
  // Begin accessing JSON data here
}

// Send request
request.send()

IE会缓存URL以加快加载速度，但如果你每隔一段时间轮询服务器以获取新信息，IE会缓存URL，并可能返回你一直拥有的相同数据集。

无论您最终如何执行GET请求——普通JavaScript、Prototype、jQuery等等——都要确保您设置了一种机制来对抗缓存。为了解决这个问题，在你要访问的URL末尾附加一个唯一的标记。这可以通过:

var sURL = '/your/url.html?' + (new Date()).getTime();

这将在URL的末尾附加一个唯一的时间戳，并将防止发生任何缓存。

你也可以用纯JS来做:

// Create the XHR object.
function createCORSRequest(method, url) {
  var xhr = new XMLHttpRequest();
if ("withCredentials" in xhr) {
// XHR for Chrome/Firefox/Opera/Safari.
xhr.open(method, url, true);
} else if (typeof XDomainRequest != "undefined") {
// XDomainRequest for IE.
xhr = new XDomainRequest();
xhr.open(method, url);
} else {
// CORS not supported.
xhr = null;
}
return xhr;
}

// Make the actual CORS request.
function makeCorsRequest() {
 // This is a sample server that supports CORS.
 var url = 'http://html5rocks-cors.s3-website-us-east-1.amazonaws.com/index.html';

var xhr = createCORSRequest('GET', url);
if (!xhr) {
alert('CORS not supported');
return;
}

// Response handlers.
xhr.onload = function() {
var text = xhr.responseText;
alert('Response from CORS request to ' + url + ': ' + text);
};

xhr.onerror = function() {
alert('Woops, there was an error making the request.');
};

xhr.send();
}

详见:html5rocks教程