我可以在IB中完全解决这个问题:

使约束使每个子视图的中心Y对齐到父视图的下边缘。 将每个约束的乘数设置为1/2n, 3/2n, 5/2n，…，n-1/2n，其中n是要分布的子视图的数量。

因此，如果您有三个标签，请将每个约束的乘数设置为0.1666667、0.5、0.833333。

在InterfaceBuilder中解决这个问题非常简单:

设置居中标签(label2)为“水平容器中心”和“垂直容器中心”

选择居中标签和顶部标签(label1 + label2)，并为垂直间距添加两个约束。大于或等于最小间距的一个。小于或等于最大间距的一个。

中间的标签和底部的标签(label2 + label3)也是如此。

此外，您还可以添加两个约束label1 -顶部空间到SuperView和两个约束label2 -底部空间到SuperView。

结果是所有4个空格的大小变化相同。

我可以在IB中完全解决这个问题:

使约束使每个子视图的中心Y对齐到父视图的下边缘。 将每个约束的乘数设置为1/2n, 3/2n, 5/2n，…，n-1/2n，其中n是要分布的子视图的数量。

因此，如果您有三个标签，请将每个约束的乘数设置为0.1666667、0.5、0.833333。

Here is a solution that will vertically center any number of subviews, even if they have unique sizes. What you want to do is make a mid-level container, center that in the superview, then put all the subviews in the container and arrange them with respect to one another. But crucially you also need to constrain them to the top and bottom of the container, so the container can be correctly sized and centered in the superview. By figuring the correct height from its subviews, the container can be vertically centered.

在本例中，self是位于所有子视图居中的父视图。

NSArray *subviews = @[ (your subviews in top-to-bottom order) ];

UIView *container = [[UIView alloc] initWithFrame:CGRectZero];
container.translatesAutoresizingMaskIntoConstraints = NO;
for (UIView *subview in subviews) {
    subview.translatesAutoresizingMaskIntoConstraints = NO;
    [container addSubview:subview];
}
[self addSubview:container];

[self addConstraint:[NSLayoutConstraint constraintWithItem:container attribute:NSLayoutAttributeLeft relatedBy:NSLayoutRelationEqual
                                                    toItem:self attribute:NSLayoutAttributeLeft multiplier:1.0f constant:0.0f]];
[self addConstraint:[NSLayoutConstraint constraintWithItem:container attribute:NSLayoutAttributeRight relatedBy:NSLayoutRelationEqual
                                                    toItem:self attribute:NSLayoutAttributeRight multiplier:1.0f constant:0.0f]];
[self addConstraint:[NSLayoutConstraint constraintWithItem:container attribute:NSLayoutAttributeCenterY relatedBy:NSLayoutRelationEqual
                                                    toItem:self attribute:NSLayoutAttributeCenterY multiplier:1.0f constant:0.0f]];

if (0 < subviews.count) {
    UIView *firstSubview = subviews[0];
    [container addConstraint:[NSLayoutConstraint constraintWithItem:firstSubview attribute:NSLayoutAttributeTop relatedBy:NSLayoutRelationEqual
                                                             toItem:container attribute:NSLayoutAttributeTop multiplier:1.0f constant:0.0f]];
    UIView *lastSubview = subviews.lastObject;
    [container addConstraint:[NSLayoutConstraint constraintWithItem:lastSubview attribute:NSLayoutAttributeBottom relatedBy:NSLayoutRelationEqual
                                                             toItem:container attribute:NSLayoutAttributeBottom multiplier:1.0f constant:0.0f]];

    UIView *subviewAbove = nil;
    for (UIView *subview in subviews) {
        [container addConstraint:[NSLayoutConstraint constraintWithItem:subview attribute:NSLayoutAttributeCenterX relatedBy:NSLayoutRelationEqual
                                                                 toItem:container attribute:NSLayoutAttributeCenterX multiplier:1.0f constant:0.0f]];
        if (subviewAbove) {
            [container addConstraint:[NSLayoutConstraint constraintWithItem:subview attribute:NSLayoutAttributeTop relatedBy:NSLayoutRelationEqual
                                                                     toItem:subviewAbove attribute:NSLayoutAttributeBottom multiplier:1.0f constant:10.0f]];
        }
        subviewAbove = subview;
    }
}

基于Ben Dolman的回答，这将更均匀地分配视图(使用填充等):

+(NSArray *)constraintsForEvenDistributionOfItems:(NSArray *)views
                           relativeToCenterOfItem:(id)toView vertically:(BOOL)vertically
{
    NSMutableArray *constraints = [NSMutableArray new];
    NSLayoutAttribute attr = vertically ? NSLayoutAttributeCenterY : NSLayoutAttributeCenterX;

    CGFloat min = 0.25;
    CGFloat max = 1.75;
    CGFloat d = (max-min) / ([views count] - 1);
    for (NSUInteger i = 0; i < [views count]; i++) {
        id view = views[i];
        CGFloat multiplier = i * d + min;
        NSLayoutConstraint *constraint = [NSLayoutConstraint constraintWithItem:view
                                                                      attribute:attr
                                                                      relatedBy:NSLayoutRelationEqual
                                                                         toItem:toView
                                                                      attribute:attr
                                                                     multiplier:multiplier
                                                                       constant:0];
        [constraints addObject:constraint];
    }

    return constraints;
}

Swift 3版本

let _redView = UIView()
        _redView.backgroundColor = UIColor.red
        _redView.translatesAutoresizingMaskIntoConstraints = false

        let _yellowView = UIView()
        _yellowView.backgroundColor = UIColor.yellow
        _yellowView.translatesAutoresizingMaskIntoConstraints = false

        let _blueView = UIView()
        _blueView.backgroundColor = UIColor.blue
        _blueView.translatesAutoresizingMaskIntoConstraints = false

        self.view.addSubview(_redView)
        self.view.addSubview(_yellowView)
        self.view.addSubview(_blueView)

        var views = ["_redView": _redView, "_yellowView": _yellowView, "_blueView":_blueView]

        var nslayoutConstraint_H = NSLayoutConstraint.constraints(withVisualFormat: "|->=0-[_redView(40)]->=0-[_yellowView(40)]->=0-[_blueView(40)]->=0-|", options: [.alignAllTop, .alignAllBottom], metrics: nil, views: views)
        self.view.addConstraints(nslayoutConstraint_H)

        var nslayoutConstraint_V = NSLayoutConstraint.constraints(withVisualFormat: "V:[_redView(60)]", options: NSLayoutFormatOptions.init(rawValue: 0), metrics: nil, views: views)
        self.view.addConstraints(nslayoutConstraint_V)


        let constraint_red = NSLayoutConstraint.init(item: self.view, attribute: .centerY, relatedBy: .equal, toItem: _redView, attribute: .centerY, multiplier: 1, constant: 0)
        self.view.addConstraint(constraint_red)

        let constraint_yellow = NSLayoutConstraint.init(item: self.view, attribute: .centerX, relatedBy: .equal, toItem: _yellowView, attribute: .centerX, multiplier: 1, constant: 0)
        self.view.addConstraint(constraint_yellow)

        let constraint_yellow1 = NSLayoutConstraint.init(item: _redView, attribute: .centerX, relatedBy: .equal, toItem: _yellowView, attribute: .leading, multiplier: 0.5, constant: 0)
        self.view.addConstraint(constraint_yellow1)

        let constraint_yellow2 = NSLayoutConstraint.init(item: _blueView, attribute: .centerX, relatedBy: .equal, toItem: _yellowView, attribute: .leading, multiplier: 1.5, constant: 40)
        self.view.addConstraint(constraint_yellow2)