我可以在IB中完全解决这个问题:

使约束使每个子视图的中心Y对齐到父视图的下边缘。 将每个约束的乘数设置为1/2n, 3/2n, 5/2n，…，n-1/2n，其中n是要分布的子视图的数量。

因此，如果您有三个标签，请将每个约束的乘数设置为0.1666667、0.5、0.833333。

另一种方法可能是让顶部和底部标签分别具有相对于视图顶部和底部的约束，并让中间视图分别具有相对于第一个和第三个视图的顶部和底部约束。

请注意，通过将视图拖到另一个视图附近，直到出现引导虚线，您可以对约束进行更多的控制——这些虚线表示将形成的两个对象之间的约束，而不是对象和父视图之间的约束。

在这种情况下，您可能希望将约束更改为“大于或等于”所需的值，而不是“等于”以允许它们调整大小。不确定这是否能达到你的目的。

大多数解决方案都依赖于项目的奇数，这样你就可以把中间的项目放在中间。如果你有偶数个项目想要平均分配呢?这是一个更一般的解。这个类别将沿垂直或水平轴均匀分布任意数量的项目。

在它们的父视图中垂直分布4个标签的示例:

[self.view addConstraints:
     [NSLayoutConstraint constraintsForEvenDistributionOfItems:@[label1, label2, label3, label4]
                                        relativeToCenterOfItem:self.view
                                                    vertically:YES]];

NSLayoutConstraint + EvenDistribution.h

@interface NSLayoutConstraint (EvenDistribution)

/**
 * Returns constraints that will cause a set of views to be evenly distributed horizontally
 * or vertically relative to the center of another item. This is used to maintain an even
 * distribution of subviews even when the superview is resized.
 */
+ (NSArray *) constraintsForEvenDistributionOfItems:(NSArray *)views
                             relativeToCenterOfItem:(id)toView
                                         vertically:(BOOL)vertically;

@end

NSLayoutConstraint + EvenDistribution.m

@implementation NSLayoutConstraint (EvenDistribution)

+(NSArray *)constraintsForEvenDistributionOfItems:(NSArray *)views
                           relativeToCenterOfItem:(id)toView vertically:(BOOL)vertically
{
    NSMutableArray *constraints = [NSMutableArray new];
    NSLayoutAttribute attr = vertically ? NSLayoutAttributeCenterY : NSLayoutAttributeCenterX;

    for (NSUInteger i = 0; i < [views count]; i++) {
        id view = views[i];
        CGFloat multiplier = (2*i + 2) / (CGFloat)([views count] + 1);
        NSLayoutConstraint *constraint = [NSLayoutConstraint constraintWithItem:view
                                                                      attribute:attr
                                                                      relatedBy:NSLayoutRelationEqual
                                                                         toItem:toView
                                                                      attribute:attr
                                                                     multiplier:multiplier
                                                                       constant:0];
        [constraints addObject:constraint];
    }

    return constraints;
}

@end

Swift 3版本

let _redView = UIView()
        _redView.backgroundColor = UIColor.red
        _redView.translatesAutoresizingMaskIntoConstraints = false

        let _yellowView = UIView()
        _yellowView.backgroundColor = UIColor.yellow
        _yellowView.translatesAutoresizingMaskIntoConstraints = false

        let _blueView = UIView()
        _blueView.backgroundColor = UIColor.blue
        _blueView.translatesAutoresizingMaskIntoConstraints = false

        self.view.addSubview(_redView)
        self.view.addSubview(_yellowView)
        self.view.addSubview(_blueView)

        var views = ["_redView": _redView, "_yellowView": _yellowView, "_blueView":_blueView]

        var nslayoutConstraint_H = NSLayoutConstraint.constraints(withVisualFormat: "|->=0-[_redView(40)]->=0-[_yellowView(40)]->=0-[_blueView(40)]->=0-|", options: [.alignAllTop, .alignAllBottom], metrics: nil, views: views)
        self.view.addConstraints(nslayoutConstraint_H)

        var nslayoutConstraint_V = NSLayoutConstraint.constraints(withVisualFormat: "V:[_redView(60)]", options: NSLayoutFormatOptions.init(rawValue: 0), metrics: nil, views: views)
        self.view.addConstraints(nslayoutConstraint_V)


        let constraint_red = NSLayoutConstraint.init(item: self.view, attribute: .centerY, relatedBy: .equal, toItem: _redView, attribute: .centerY, multiplier: 1, constant: 0)
        self.view.addConstraint(constraint_red)

        let constraint_yellow = NSLayoutConstraint.init(item: self.view, attribute: .centerX, relatedBy: .equal, toItem: _yellowView, attribute: .centerX, multiplier: 1, constant: 0)
        self.view.addConstraint(constraint_yellow)

        let constraint_yellow1 = NSLayoutConstraint.init(item: _redView, attribute: .centerX, relatedBy: .equal, toItem: _yellowView, attribute: .leading, multiplier: 0.5, constant: 0)
        self.view.addConstraint(constraint_yellow1)

        let constraint_yellow2 = NSLayoutConstraint.init(item: _blueView, attribute: .centerX, relatedBy: .equal, toItem: _yellowView, attribute: .leading, multiplier: 1.5, constant: 40)
        self.view.addConstraint(constraint_yellow2)

迟到的派对，但我有一个工作的解决方案，创建一个菜单水平间距。在NSLayoutConstraint中使用==可以很容易地做到这一点

const float MENU_HEIGHT = 40;

- (UIView*) createMenuWithLabels: (NSArray *) labels
    // labels is NSArray of NSString
    UIView * backgroundView = [[UIView alloc]init];
    backgroundView.translatesAutoresizingMaskIntoConstraints = false;

    NSMutableDictionary * views = [[NSMutableDictionary alloc] init];
    NSMutableString * format = [[NSMutableString alloc] initWithString: @"H:|"];
    NSString * firstLabelKey;

    for(NSString * str in labels)
    {
        UILabel * label = [[UILabel alloc] init];
        label.translatesAutoresizingMaskIntoConstraints = false;
        label.text = str;
        label.textAlignment = NSTextAlignmentCenter;
        label.textColor = [UIColor whiteColor];
        [backgroundView addSubview: label];
        [label fixHeightToTopBounds: MENU_HEIGHT-2];
        [backgroundView addConstraints: [label fixHeightToTopBounds: MENU_HEIGHT]];
        NSString * key = [self camelCaseFromString: str];
        [views setObject: label forKey: key];
        if(firstLabelKey == nil)
        {
            [format appendString: [NSString stringWithFormat: @"[%@]", key]];
            firstLabelKey = key;
        }
        else
        {
            [format appendString: [NSString stringWithFormat: @"[%@(==%@)]", key, firstLabelKey]];
        }
    }

    [format appendString: @"|"];

    NSArray * constraints = [NSLayoutConstraint constraintsWithVisualFormat: (NSString *) format
                                                                               options: 0
                                                                               metrics: nil
                                                                                 views: (NSDictionary *) views];
    [backgroundView addConstraints: constraints];
    return backgroundView;
}

基于Ben Dolman的回答，这将更均匀地分配视图(使用填充等):

+(NSArray *)constraintsForEvenDistributionOfItems:(NSArray *)views
                           relativeToCenterOfItem:(id)toView vertically:(BOOL)vertically
{
    NSMutableArray *constraints = [NSMutableArray new];
    NSLayoutAttribute attr = vertically ? NSLayoutAttributeCenterY : NSLayoutAttributeCenterX;

    CGFloat min = 0.25;
    CGFloat max = 1.75;
    CGFloat d = (max-min) / ([views count] - 1);
    for (NSUInteger i = 0; i < [views count]; i++) {
        id view = views[i];
        CGFloat multiplier = i * d + min;
        NSLayoutConstraint *constraint = [NSLayoutConstraint constraintWithItem:view
                                                                      attribute:attr
                                                                      relatedBy:NSLayoutRelationEqual
                                                                         toItem:toView
                                                                      attribute:attr
                                                                     multiplier:multiplier
                                                                       constant:0];
        [constraints addObject:constraint];
    }

    return constraints;
}