在我看来，最好和最快的选择是在其他地方重写文件，而不是将所有内容存储在一个列表中并重新打开文件来写入。

with open("yourfile.txt", "r") as file_input:
    with open("newfile.txt", "w") as output: 
        for line in file_input:
            if line.strip("\n") != "nickname_to_delete":
                output.write(line)

就是这样!在一个且只有一个循环中，你可以做同样的事情。这样会快得多。

按行号删除文件中的某一行。

用文件名和要删除的行号替换变量filename和line_to_delete。

filename = 'foo.txt'
line_to_delete = 3
initial_line = 1
file_lines = {}

with open(filename) as f:
    content = f.readlines() 

for line in content:
    file_lines[initial_line] = line.strip()
    initial_line += 1

f = open(filename, "w")
for line_number, line_content in file_lines.items():
    if line_number != line_to_delete:
        f.write('{}\n'.format(line_content))

f.close()
print('Deleted line: {}'.format(line_to_delete))

示例输出:

Deleted line: 3

首先，打开文件并从文件中获取所有的行。然后以写模式重新打开文件，写回你想要删除的行:

with open("yourfile.txt", "r") as f:
    lines = f.readlines()
with open("yourfile.txt", "w") as f:
    for line in lines:
        if line.strip("\n") != "nickname_to_delete":
            f.write(line)

您需要去掉比较中的换行符(“\n”)，因为如果您的文件不以换行符结束，那么最后一行也不会以换行符结束。

你想从文件中删除特定的行，所以使用这个简短的代码片段，你可以很容易地删除任何带有句子或前缀(符号)的行。

with open("file_name.txt", "r") as f:
lines = f.readlines() 
with open("new_file.txt", "w") as new_f:
    for line in lines:
        if not line.startswith("write any sentence or symbol to remove line"):
            new_f.write(line)

下面是其他一些从文件中删除/some行的方法:

src_file = zzzz.txt
f = open(src_file, "r")
contents = f.readlines()
f.close()

contents.pop(idx) # remove the line item from list, by line number, starts from 0

f = open(src_file, "w")
contents = "".join(contents)
f.write(contents)
f.close()

也许你已经有了正确答案，但下面是我的答案。 我没有使用列表来收集未经过滤的数据(readlines()方法所做的)，而是使用了两个文件。一个用于保存主数据，第二个用于在删除特定字符串时过滤数据。这是一个代码:

main_file = open('data_base.txt').read()    # your main dataBase file
filter_file = open('filter_base.txt', 'w')
filter_file.write(main_file)
filter_file.close()
main_file = open('data_base.txt', 'w')
for line in open('filter_base'):
    if 'your data to delete' not in line:    # remove a specific string
        main_file.write(line)                # put all strings back to your db except deleted
    else: pass
main_file.close()

希望你会发现这有用!：）