简单的回答是:

_textBox.TextChanged += delegate(System.Object o, System.EventArgs e)
{
    TextBox _tbox = o as TextBox;
    _tbox.Text = new string(_tbox.Text.Where(c => (char.IsDigit(c)) || (c == '.')).ToArray());
};

这可能有用。它允许“真实”数值，包括正确的小数点和前面的加号或减号。从相关的KeyPress事件中调用它。

       private bool IsOKForDecimalTextBox(char theCharacter, TextBox theTextBox)
    {
        // Only allow control characters, digits, plus and minus signs.
        // Only allow ONE plus sign.
        // Only allow ONE minus sign.
        // Only allow the plus or minus sign as the FIRST character.
        // Only allow ONE decimal point.
        // Do NOT allow decimal point or digits BEFORE any plus or minus sign.

        if (
            !char.IsControl(theCharacter)
            && !char.IsDigit(theCharacter)
            && (theCharacter != '.')
            && (theCharacter != '-')
            && (theCharacter != '+')
        )
        {
            // Then it is NOT a character we want allowed in the text box.
            return false;
        }



        // Only allow one decimal point.
        if (theCharacter == '.'
            && theTextBox.Text.IndexOf('.') > -1)
        {
            // Then there is already a decimal point in the text box.
            return false;
        }

        // Only allow one minus sign.
        if (theCharacter == '-'
            && theTextBox.Text.IndexOf('-') > -1)
        {
            // Then there is already a minus sign in the text box.
            return false;
        }

        // Only allow one plus sign.
        if (theCharacter == '+'
            && theTextBox.Text.IndexOf('+') > -1)
        {
            // Then there is already a plus sign in the text box.
            return false;
        }

        // Only allow one plus sign OR minus sign, but not both.
        if (
            (
                (theCharacter == '-')
                || (theCharacter == '+')
            )
            && 
            (
                (theTextBox.Text.IndexOf('-') > -1)
                ||
                (theTextBox.Text.IndexOf('+') > -1)
            )
            )
        {
            // Then the user is trying to enter a plus or minus sign and
            // there is ALREADY a plus or minus sign in the text box.
            return false;
        }

        // Only allow a minus or plus sign at the first character position.
        if (
            (
                (theCharacter == '-')
                || (theCharacter == '+')
            )
            && theTextBox.SelectionStart != 0
            )
        {
            // Then the user is trying to enter a minus or plus sign at some position 
            // OTHER than the first character position in the text box.
            return false;
        }

        // Only allow digits and decimal point AFTER any existing plus or minus sign
        if  (
                (
                    // Is digit or decimal point
                    char.IsDigit(theCharacter)
                    ||
                    (theCharacter == '.')
                )
                &&
                (
                    // A plus or minus sign EXISTS
                    (theTextBox.Text.IndexOf('-') > -1)
                    ||
                    (theTextBox.Text.IndexOf('+') > -1)
                )
                &&
                    // Attempting to put the character at the beginning of the field.
                    theTextBox.SelectionStart == 0
            )
        {
            // Then the user is trying to enter a digit or decimal point in front of a minus or plus sign.
            return false;
        }

        // Otherwise the character is perfectly fine for a decimal value and the character
        // may indeed be placed at the current insertion position.
        return true;
    }

最简单粗暴的方法是使用组合框而不是带有只读的文本框。当然，只有当你希望用户使用一个合理的整数集，而不是试图接近无穷大时，它才有用。

整数和浮点数都需要被接受，包括负数。

private void textBox1_KeyPress(object sender, KeyPressEventArgs e)
{
    // Text
    string text = ((Control) sender).Text;

    // Is Negative Number?
    if (e.KeyChar == '-' && text.Length == 0)
    {
        e.Handled = false;
        return;
    }

    // Is Float Number?
    if (e.KeyChar == '.' && text.Length > 0 && !text.Contains("."))
    {
        e.Handled = false;
        return;
    }

    // Is Digit?
    e.Handled = (!char.IsDigit(e.KeyChar) && !char.IsControl(e.KeyChar));
}

你可以使用TextChanged/ Keypress事件，使用正则表达式过滤数字，并采取一些行动。

简单的回答是:

_textBox.TextChanged += delegate(System.Object o, System.EventArgs e)
{
    TextBox _tbox = o as TextBox;
    _tbox.Text = new string(_tbox.Text.Where(c => (char.IsDigit(c)) || (c == '.')).ToArray());
};