现代Python（3.6+）使用pathlib模块对路径进行类似OOP的简洁处理，使用pathlib.Path.rglob（）进行递归globing。据我所知，这相当于乔治·V·莱利的回答：压缩压缩，最顶层的元素是目录，保持空目录，使用相对路径。

from pathlib import Path
from zipfile import ZIP_DEFLATED, ZipFile

from os import PathLike
from typing import Union


def zip_dir(zip_name: str, source_dir: Union[str, PathLike]):
    src_path = Path(source_dir).expanduser().resolve(strict=True)
    with ZipFile(zip_name, 'w', ZIP_DEFLATED) as zf:
        for file in src_path.rglob('*'):
            zf.write(file, file.relative_to(src_path.parent))

注意：如可选类型提示所示，zip_name不能是Path对象（将在3.6.2+中修复）。

下面是Nux给出的答案的一个变体，对我有用：

def WriteDirectoryToZipFile( zipHandle, srcPath, zipLocalPath = "", zipOperation = zipfile.ZIP_DEFLATED ):
    basePath = os.path.split( srcPath )[ 0 ]
    for root, dirs, files in os.walk( srcPath ):
        p = os.path.join( zipLocalPath, root [ ( len( basePath ) + 1 ) : ] )
        # add dir
        zipHandle.write( root, p, zipOperation )
        # add files
        for f in files:
            filePath = os.path.join( root, f )
            fileInZipPath = os.path.join( p, f )
            zipHandle.write( filePath, fileInZipPath, zipOperation )

我对Mark Byers给出的代码做了一些修改。如果您有空目录，下面的函数也会添加它们。示例应该更清楚添加到zip的路径是什么。

#!/usr/bin/env python
import os
import zipfile

def addDirToZip(zipHandle, path, basePath=""):
    """
    Adding directory given by \a path to opened zip file \a zipHandle

    @param basePath path that will be removed from \a path when adding to archive

    Examples:
        # add whole "dir" to "test.zip" (when you open "test.zip" you will see only "dir")
        zipHandle = zipfile.ZipFile('test.zip', 'w')
        addDirToZip(zipHandle, 'dir')
        zipHandle.close()

        # add contents of "dir" to "test.zip" (when you open "test.zip" you will see only it's contents)
        zipHandle = zipfile.ZipFile('test.zip', 'w')
        addDirToZip(zipHandle, 'dir', 'dir')
        zipHandle.close()

        # add contents of "dir/subdir" to "test.zip" (when you open "test.zip" you will see only contents of "subdir")
        zipHandle = zipfile.ZipFile('test.zip', 'w')
        addDirToZip(zipHandle, 'dir/subdir', 'dir/subdir')
        zipHandle.close()

        # add whole "dir/subdir" to "test.zip" (when you open "test.zip" you will see only "subdir")
        zipHandle = zipfile.ZipFile('test.zip', 'w')
        addDirToZip(zipHandle, 'dir/subdir', 'dir')
        zipHandle.close()

        # add whole "dir/subdir" with full path to "test.zip" (when you open "test.zip" you will see only "dir" and inside it only "subdir")
        zipHandle = zipfile.ZipFile('test.zip', 'w')
        addDirToZip(zipHandle, 'dir/subdir')
        zipHandle.close()

        # add whole "dir" and "otherDir" (with full path) to "test.zip" (when you open "test.zip" you will see only "dir" and "otherDir")
        zipHandle = zipfile.ZipFile('test.zip', 'w')
        addDirToZip(zipHandle, 'dir')
        addDirToZip(zipHandle, 'otherDir')
        zipHandle.close()
    """
    basePath = basePath.rstrip("\\/") + ""
    basePath = basePath.rstrip("\\/")
    for root, dirs, files in os.walk(path):
        # add dir itself (needed for empty dirs
        zipHandle.write(os.path.join(root, "."))
        # add files
        for file in files:
            filePath = os.path.join(root, file)
            inZipPath = filePath.replace(basePath, "", 1).lstrip("\\/")
            #print filePath + " , " + inZipPath
            zipHandle.write(filePath, inZipPath)

以上是一个简单的函数，适用于简单的情况。你可以在我的Gist中找到更优雅的课程：https://gist.github.com/Eccenux/17526123107ca0ac28e6

函数创建zip文件。

def CREATEZIPFILE(zipname, path):
    #function to create a zip file
    #Parameters: zipname - name of the zip file; path - name of folder/file to be put in zip file

    zipf = zipfile.ZipFile(zipname, 'w', zipfile.ZIP_DEFLATED)
    zipf.setpassword(b"password") #if you want to set password to zipfile

    #checks if the path is file or directory
    if os.path.isdir(path):
        for files in os.listdir(path):
            zipf.write(os.path.join(path, files), files)

    elif os.path.isfile(path):
        zipf.write(os.path.join(path), path)
    zipf.close()

最简单的方法是使用shutil.make_archive。它支持zip和tar格式。

import shutil
shutil.make_archive(output_filename, 'zip', dir_name)

如果您需要做一些比压缩整个目录更复杂的事情（例如跳过某些文件），那么您需要像其他人建议的那样深入到zipfile模块。

要将mydirectory的内容添加到新的zip文件中，包括所有文件和子目录：

import os
import zipfile

zf = zipfile.ZipFile("myzipfile.zip", "w")
for dirname, subdirs, files in os.walk("mydirectory"):
    zf.write(dirname)
    for filename in files:
        zf.write(os.path.join(dirname, filename))
zf.close()