如果您想要一个类似于任何通用图形文件管理器的压缩文件夹的功能，可以使用以下代码，它使用zipfile模块。使用这段代码，您将得到以路径为根文件夹的zip文件。

import os
import zipfile

def zipdir(path, ziph):
    # Iterate all the directories and files
    for root, dirs, files in os.walk(path):
        # Create a prefix variable with the folder structure inside the path folder. 
        # So if a file is at the path directory will be at the root directory of the zip file
        # so the prefix will be empty. If the file belongs to a containing folder of path folder 
        # then the prefix will be that folder.
        if root.replace(path,'') == '':
                prefix = ''
        else:
                # Keep the folder structure after the path folder, append a '/' at the end 
                # and remome the first character, if it is a '/' in order to have a path like 
                # folder1/folder2/file.txt
                prefix = root.replace(path, '') + '/'
                if (prefix[0] == '/'):
                        prefix = prefix[1:]
        for filename in files:
                actual_file_path = root + '/' + filename
                zipped_file_path = prefix + filename
                zipf.write( actual_file_path, zipped_file_path)


zipf = zipfile.ZipFile('Python.zip', 'w', zipfile.ZIP_DEFLATED)
zipdir('/tmp/justtest/', zipf)
zipf.close()

我还有另一个代码示例可能会有所帮助，使用python3、pathlib和zipfile。它应该可以在任何操作系统中工作。

from pathlib import Path
import zipfile
from datetime import datetime

DATE_FORMAT = '%y%m%d'


def date_str():
    """returns the today string year, month, day"""
    return '{}'.format(datetime.now().strftime(DATE_FORMAT))


def zip_name(path):
    """returns the zip filename as string"""
    cur_dir = Path(path).resolve()
    parent_dir = cur_dir.parents[0]
    zip_filename = '{}/{}_{}.zip'.format(parent_dir, cur_dir.name, date_str())
    p_zip = Path(zip_filename)
    n = 1
    while p_zip.exists():
        zip_filename = ('{}/{}_{}_{}.zip'.format(parent_dir, cur_dir.name,
                                             date_str(), n))
        p_zip = Path(zip_filename)
        n += 1
    return zip_filename


def all_files(path):
    """iterator returns all files and folders from path as absolute path string
    """
    for child in Path(path).iterdir():
        yield str(child)
        if child.is_dir():
            for grand_child in all_files(str(child)):
                yield str(Path(grand_child))


def zip_dir(path):
    """generate a zip"""
    zip_filename = zip_name(path)
    zip_file = zipfile.ZipFile(zip_filename, 'w')
    print('create:', zip_filename)
    for file in all_files(path):
        print('adding... ', file)
        zip_file.write(file)
    zip_file.close()


if __name__ == '__main__':
    zip_dir('.')
    print('end!')

现代Python（3.6+）使用pathlib模块对路径进行类似OOP的简洁处理，使用pathlib.Path.rglob（）进行递归globing。据我所知，这相当于乔治·V·莱利的回答：压缩压缩，最顶层的元素是目录，保持空目录，使用相对路径。

from pathlib import Path
from zipfile import ZIP_DEFLATED, ZipFile

from os import PathLike
from typing import Union


def zip_dir(zip_name: str, source_dir: Union[str, PathLike]):
    src_path = Path(source_dir).expanduser().resolve(strict=True)
    with ZipFile(zip_name, 'w', ZIP_DEFLATED) as zf:
        for file in src_path.rglob('*'):
            zf.write(file, file.relative_to(src_path.parent))

注意：如可选类型提示所示，zip_name不能是Path对象（将在3.6.2+中修复）。

前面的答案完全忽略了一点，即当您在Windows上运行代码时，使用os.path.join（）可以很容易地返回POSIX不兼容的路径。当使用Linux上的任何常用归档软件处理文件时，生成的归档文件将包含名称中带有反斜杠的文件，这不是您想要的。请改用path.as_posix（）作为arcname参数！

import zipfile
from pathlib import Path
with zipfile.ZipFile("archive.zip", "w", zipfile.ZIP_DEFLATED) as zf:
    for path in Path("include_all_of_this_folder").rglob("*"):
        zf.write(path, path.as_posix())

要提供更大的灵活性，例如按名称选择目录/文件，请使用：

import os
import zipfile

def zipall(ob, path, rel=""):
    basename = os.path.basename(path)
    if os.path.isdir(path):
        if rel == "":
            rel = basename
        ob.write(path, os.path.join(rel))
        for root, dirs, files in os.walk(path):
            for d in dirs:
                zipall(ob, os.path.join(root, d), os.path.join(rel, d))
            for f in files:
                ob.write(os.path.join(root, f), os.path.join(rel, f))
            break
    elif os.path.isfile(path):
        ob.write(path, os.path.join(rel, basename))
    else:
        pass

对于文件树：

.
├── dir
│   ├── dir2
│   │   └── file2.txt
│   ├── dir3
│   │   └── file3.txt
│   └── file.txt
├── dir4
│   ├── dir5
│   └── file4.txt
├── listdir.zip
├── main.py
├── root.txt
└── selective.zip

例如，您可以只选择dir4和root.txt：

cwd = os.getcwd()
files = [os.path.join(cwd, f) for f in ['dir4', 'root.txt']]

with zipfile.ZipFile("selective.zip", "w" ) as myzip:
    for f in files:
        zipall(myzip, f)

或者只需在脚本调用目录中列出目录，然后从中添加所有内容：

with zipfile.ZipFile("listdir.zip", "w" ) as myzip:
    for f in os.listdir():
        if f == "listdir.zip":
            # Creating a listdir.zip in the same directory
            # will include listdir.zip inside itself, beware of this
            continue
        zipall(myzip, f)

要将mydirectory的内容添加到新的zip文件中，包括所有文件和子目录：

import os
import zipfile

zf = zipfile.ZipFile("myzipfile.zip", "w")
for dirname, subdirs, files in os.walk("mydirectory"):
    zf.write(dirname)
    for filename in files:
        zf.write(os.path.join(dirname, filename))
zf.close()