在这种情况下，你可以尝试，

UILabel *displayLabel = [[UILabel alloc] initWithFrame:/*label frame*/];
displayLabel.font = [UIFont boldSystemFontOfSize:/*bold font size*/];

NSMutableAttributedString *notifyingStr = [[NSMutableAttributedString alloc] initWithString:@"Updated: 2012/10/14 21:59 PM"];
[notifyingStr beginEditing];
[notifyingStr addAttribute:NSFontAttributeName
                     value:[UIFont systemFontOfSize:/*normal font size*/]
                     range:NSMakeRange(8,10)/*range of normal string, e.g. 2012/10/14*/];
[notifyingStr endEditing];

displayLabel.attributedText = notifyingStr; // or [displayLabel setAttributedText: notifyingStr];

试试UILabel上的分类:

下面是它的用法:

myLabel.text = @"Updated: 2012/10/14 21:59 PM";
[myLabel boldSubstring: @"Updated:"];
[myLabel boldSubstring: @"21:59 PM"];

这是分类

UILabel h +及。

- (void) boldSubstring: (NSString*) substring;
- (void) boldRange: (NSRange) range;

UILabel + Boldify.m

- (void) boldRange: (NSRange) range {
    if (![self respondsToSelector:@selector(setAttributedText:)]) {
        return;
    }
    NSMutableAttributedString *attributedText = [[NSMutableAttributedString alloc] initWithAttributedString:self.attributedText];
    [attributedText setAttributes:@{NSFontAttributeName:[UIFont boldSystemFontOfSize:self.font.pointSize]} range:range];

    self.attributedText = attributedText;    
}

- (void) boldSubstring: (NSString*) substring {
    NSRange range = [self.text rangeOfString:substring];
    [self boldRange:range];
}

注意，这只适用于iOS 6及更高版本。在iOS 5或更早的版本中，它将被忽略。

这招对我很管用:

CGFloat boldTextFontSize = 17.0f;

myLabel.text = [NSString stringWithFormat:@"%@ 2012/10/14 %@",@"Updated:",@"21:59 PM"];

NSRange range1 = [myLabel.text rangeOfString:@"Updated:"];
NSRange range2 = [myLabel.text rangeOfString:@"21:59 PM"];

NSMutableAttributedString *attributedText = [[NSMutableAttributedString alloc] initWithString:myLabel.text];

[attributedText setAttributes:@{NSFontAttributeName:[UIFont boldSystemFontOfSize:boldTextFontSize]}
                        range:range1];
[attributedText setAttributes:@{NSFontAttributeName:[UIFont boldSystemFontOfSize:boldTextFontSize]}
                        range:range2];

myLabel.attributedText = attributedText;

对于Swift版本:见这里

NSString *needToChangeStr=@"BOOK";
NSString *display_string=[NSString stringWithFormat:@"This is %@",book];

NSMutableAttributedString *attri_str=[[NSMutableAttributedString alloc]initWithString:display_string];

int begin=[display_string length]-[needToChangeStr length];
int end=[needToChangeStr length];


[attri_str addAttribute:NSFontAttributeName value:[UIFont fontWithName:@"HelveticaNeue-Bold" size:30] range:NSMakeRange(begin, end)];

我采用了疯狂酸奶对斯威夫特扩展的回答。

extension UILabel {

    func boldRange(_ range: Range<String.Index>) {
        if let text = self.attributedText {
            let attr = NSMutableAttributedString(attributedString: text)
            let start = text.string.characters.distance(from: text.string.startIndex, to: range.lowerBound)
            let length = text.string.characters.distance(from: range.lowerBound, to: range.upperBound)
            attr.addAttributes([NSFontAttributeName: UIFont.boldSystemFont(ofSize: self.font.pointSize)], range: NSMakeRange(start, length))
            self.attributedText = attr
        }
    }

    func boldSubstring(_ substr: String) {
        if let text = self.attributedText {
            var range = text.string.range(of: substr)
            let attr = NSMutableAttributedString(attributedString: text)
            while range != nil {
                let start = text.string.characters.distance(from: text.string.startIndex, to: range!.lowerBound)
                let length = text.string.characters.distance(from: range!.lowerBound, to: range!.upperBound)
                var nsRange = NSMakeRange(start, length)
                let font = attr.attribute(NSFontAttributeName, at: start, effectiveRange: &nsRange) as! UIFont
                if !font.fontDescriptor.symbolicTraits.contains(.traitBold) {
                    break
                }
                range = text.string.range(of: substr, options: NSString.CompareOptions.literal, range: range!.upperBound..<text.string.endIndex, locale: nil)
            }
            if let r = range {
                boldRange(r)
            }
        }
    }
}

可能在Range和NSRange之间没有很好的转换，但我没有发现更好的东西。

如果您希望更容易地使用带属性字符串，请尝试使用带属性字符串创建者，它将为您生成代码。https://itunes.apple.com/us/app/attributed-string-creator/id730928349