这招对我很管用:

CGFloat boldTextFontSize = 17.0f;

myLabel.text = [NSString stringWithFormat:@"%@ 2012/10/14 %@",@"Updated:",@"21:59 PM"];

NSRange range1 = [myLabel.text rangeOfString:@"Updated:"];
NSRange range2 = [myLabel.text rangeOfString:@"21:59 PM"];

NSMutableAttributedString *attributedText = [[NSMutableAttributedString alloc] initWithString:myLabel.text];

[attributedText setAttributes:@{NSFontAttributeName:[UIFont boldSystemFontOfSize:boldTextFontSize]}
                        range:range1];
[attributedText setAttributes:@{NSFontAttributeName:[UIFont boldSystemFontOfSize:boldTextFontSize]}
                        range:range2];

myLabel.attributedText = attributedText;

对于Swift版本:见这里

如果您希望更容易地使用带属性字符串，请尝试使用带属性字符串创建者，它将为您生成代码。https://itunes.apple.com/us/app/attributed-string-creator/id730928349

斯威夫特4:

// attribute with color red and Bold
var attrs1 = [NSAttributedStringKey.font: UIFont.boldSystemFont(ofSize: 20), NSAttributedStringKey.foregroundColor: UIColor.red]

// attribute with color black and Non Bold
var attrs2 = [NSAttributedStringKey.font: UIFont(name: "Roboto-Regular", size: 20), NSAttributedStringKey.foregroundColor: UIColor.black]  

var color1 = NSAttributedString(string: "RED", attributes: attrs1)

var color2 = NSAttributedString(string: " BLACK", attributes: attrs2)

var string = NSMutableAttributedString()

string.append(color1)

string.append(color2)

// print the text with **RED** BLACK
print("Final String : \(string)")

NSString *needToChangeStr=@"BOOK";
NSString *display_string=[NSString stringWithFormat:@"This is %@",book];

NSMutableAttributedString *attri_str=[[NSMutableAttributedString alloc]initWithString:display_string];

int begin=[display_string length]-[needToChangeStr length];
int end=[needToChangeStr length];


[attri_str addAttribute:NSFontAttributeName value:[UIFont fontWithName:@"HelveticaNeue-Bold" size:30] range:NSMakeRange(begin, end)];

在这种情况下，你可以尝试，

UILabel *displayLabel = [[UILabel alloc] initWithFrame:/*label frame*/];
displayLabel.font = [UIFont boldSystemFontOfSize:/*bold font size*/];

NSMutableAttributedString *notifyingStr = [[NSMutableAttributedString alloc] initWithString:@"Updated: 2012/10/14 21:59 PM"];
[notifyingStr beginEditing];
[notifyingStr addAttribute:NSFontAttributeName
                     value:[UIFont systemFontOfSize:/*normal font size*/]
                     range:NSMakeRange(8,10)/*range of normal string, e.g. 2012/10/14*/];
[notifyingStr endEditing];

displayLabel.attributedText = notifyingStr; // or [displayLabel setAttributedText: notifyingStr];

这在Interface Builder中很容易做到:

1)在属性检查器中设置UILabel为Attributes

2)选择你想加粗的部分短语

3)在字体选择器中更改其字体(或相同字体的粗体)

这是所有!