一种简单的方法是使用next()的可选参数，如果生成器耗尽(或为空)，则使用该参数。例如:

_exhausted  = object()

if next(some_generator, _exhausted) is _exhausted:
    print('generator is empty')

建议:

def peek(iterable):
    try:
        first = next(iterable)
    except StopIteration:
        return None
    return first, itertools.chain([first], iterable)

用法:

res = peek(mysequence)
if res is None:
    # sequence is empty.  Do stuff.
else:
    first, mysequence = res
    # Do something with first, maybe?
    # Then iterate over the sequence:
    for element in mysequence:
        # etc.

恕我直言，最好的办法是避免特殊测试。大多数时候，使用生成器是一种测试:

thing_generated = False

# Nothing is lost here. if nothing is generated, 
# the for block is not executed. Often, that's the only check
# you need to do. This can be done in the course of doing
# the work you wanted to do anyway on the generated output.
for thing in my_generator():
    thing_generated = True
    do_work(thing)

如果这还不够好，您仍然可以执行显式测试。此时，thing将包含最后生成的值。如果没有生成任何内容，它将是未定义的—除非您已经定义了该变量。你可以检查东西的价值，但那有点不可靠。相反，只需在块内设置一个标志，然后检查它:

if not thing_generated:
    print "Avast, ye scurvy dog!"

我意识到这篇文章已经5年了，但我在寻找一种惯用的方法时发现了它，并没有看到我的解决方案发布出来。所以为了子孙后代:

import itertools

def get_generator():
    """
    Returns (bool, generator) where bool is true iff the generator is not empty.
    """
    gen = (i for i in [0, 1, 2, 3, 4])
    a, b = itertools.tee(gen)
    try:
        a.next()
    except StopIteration:
        return (False, b)
    return (True, b)

当然，我相信许多评论员会指出，这很俗气，而且只在某些有限的情况下有效(例如，生成器没有副作用)。YMMV。

刚刚读到这篇文章，意识到缺少一个非常简单易懂的答案:

def is_empty(generator):
    for item in generator:
        return False
    return True

如果我们不打算使用任何项，那么我们需要将第一项重新注入生成器:

def is_empty_no_side_effects(generator):
    try:
        item = next(generator)
        def my_generator():
            yield item
            yield from generator
        return my_generator(), False
    except StopIteration:
        return (_ for _ in []), True

例子:

>>> g=(i for i in [])
>>> g,empty=is_empty_no_side_effects(g)
>>> empty
True
>>> g=(i for i in range(10))
>>> g,empty=is_empty_no_side_effects(g)
>>> empty
False
>>> list(g)
[0, 1, 2, 3, 4, 5, 6, 7, 8, 9]

Bool (generator)将返回正确的结果