你可以使用Proxy的构造句柄来做到这一点，代码如下:

const SomeClass = new Proxy(class A {
  constructor(user) {
    this.user = user;
  }
}, {
  async construct(target, args, newTarget) {
    const [name] = args;
    // you can use await in here
    const user = await fetch(name);
    // invoke new A here
    return new target(user);
  }
});

const a = await new SomeClass('cage');
console.log(a.user); // user info

其他答案都忽略了一个显而易见的事实。简单地从你的构造函数调用一个async函数:

constructor() {
    setContentAsync();
}

async setContentAsync() {
    let uid = this.getAttribute('data-uid')
    let message = await grabUID(uid)

    const shadowRoot = this.attachShadow({mode: 'open'})
    shadowRoot.innerHTML = `
      <div id="email">A random email message has appeared. ${message}</div>
    `
}

您应该将该函数添加到实例中。Promise将它识别为Promise的可支持对象。解决自动

const asyncSymbol = Symbol();
class MyClass {
    constructor() {
        this.asyncData = null
    }
    then(resolve, reject) {
        return (this[asyncSymbol] = this[asyncSymbol] || new Promise((innerResolve, innerReject) => {
            this.asyncData = { a: 1 }
            setTimeout(() => innerResolve(this.asyncData), 3000)
        })).then(resolve, reject)
    }
}

async function wait() {
    const asyncData = await new MyClass();
    alert('run 3s later')
    alert(asyncData.a)
}

根据您的注释，您可能应该做其他带有资产加载的HTMLElement所做的事情:使构造函数启动一个侧加载操作，根据结果生成一个加载或错误事件。

是的，这意味着使用承诺，但这也意味着“以与其他HTML元素相同的方式做事”，所以你是一个很好的公司。例如:

var img = new Image();
img.onload = function(evt) { ... }
img.addEventListener("load", evt => ... );
img.onerror = function(evt) { ... }
img.addEventListener("error", evt => ... );
img.src = "some url";

这将启动源资产的异步加载，当它成功时，以onload结束，当它出错时，以onerror结束。所以，让你自己的类也这样做:

class EMailElement extends HTMLElement {
  connectedCallback() {
    this.uid = this.getAttribute('data-uid');
  }

  setAttribute(name, value) {
    super.setAttribute(name, value);
    if (name === 'data-uid') {
      this.uid = value;
    }
  }

  set uid(input) {
    if (!input) return;
    const uid = parseInt(input);
    // don't fight the river, go with the flow, use a promise:
    new Promise((resolve, reject) => {
      yourDataBase.getByUID(uid, (err, result) => {
        if (err) return reject(err);
        resolve(result);
      });
    })
    .then(result => {
      this.renderLoaded(result.message);
    })
    .catch(error => {
      this.renderError(error);
    });
  }
};

customElements.define('e-mail', EmailElement);

然后你让renderLoaded/renderError函数处理事件调用和shadow dom:

  renderLoaded(message) {
    const shadowRoot = this.attachShadow({mode: 'open'});
    shadowRoot.innerHTML = `
      <div class="email">A random email message has appeared. ${message}</div>
    `;
    // is there an ancient event listener?
    if (this.onload) {
      this.onload(...);
    }
    // there might be modern event listeners. dispatch an event.
    this.dispatchEvent(new Event('load'));
  }

  renderFailed() {
    const shadowRoot = this.attachShadow({mode: 'open'});
    shadowRoot.innerHTML = `
      <div class="email">No email messages.</div>
    `;
    // is there an ancient event listener?
    if (this.onload) {
      this.onerror(...);
    }
    // there might be modern event listeners. dispatch an event.
    this.dispatchEvent(new Event('error'));
  }

还要注意，我将id更改为一个类，因为除非您编写一些奇怪的代码，只允许页面上的<e-mail>元素的单个实例，否则您不能使用唯一标识符，然后将其分配给一堆元素。

构建器模式的变体，使用call():

function asyncMethod(arg) {
    function innerPromise() { return new Promise((...)=> {...}) }
    innerPromise().then(result => {
        this.setStuff(result);
    }
}

const getInstance = async (arg) => {
    let instance = new Instance();
    await asyncMethod.call(instance, arg);
    return instance;
}

这里有很多伟大的知识和一些超级()深思熟虑的回答。简而言之，下面概述的技术相当简单、非递归、异步兼容，并且遵循规则。更重要的是，我认为这里还没有正确地覆盖它-尽管如果错误请纠正我!

我们不调用方法，而是简单地将II(A)FE赋值给实例prop:

// it's async-lite!
class AsyncLiteComponent {
  constructor() {
    // our instance includes a 'ready' property: an IIAFE promise
    // that auto-runs our async needs and then resolves to the instance
    // ...
    // this is the primary difference to other answers, in that we defer
    // from a property, not a method, and the async functionality both
    // auto-runs and the promise/prop resolves to the instance
    this.ready = (async () => {
      // in this example we're auto-fetching something
      this.msg = await AsyncLiteComponent.msg;
      // we return our instance to allow nifty one-liners (see below)
      return this;
    })();
  }

  // we keep our async functionality in a static async getter
  // ... technically (with some minor tweaks), we could prefetch
  // or cache this response (but that isn't really our goal here)
  static get msg() {
    // yes I know - this example returns almost immediately (imagination people!)
    return fetch('data:,Hello%20World%21').then((e) => e.text());
  }
}

看起来很简单，怎么用呢?

// Ok, so you *could* instantiate it the normal, excessively boring way
const iwillnotwait = new AsyncLiteComponent();
// and defer your waiting for later
await iwillnotwait.ready
console.log(iwillnotwait.msg)

// OR OR OR you can get all async/awaity about it!
const onlywhenimready = await new AsyncLiteComponent().ready;
console.log(onlywhenimready.msg)

// ... if you're really antsy you could even "pre-wait" using the static method,
// but you'd probably want some caching / update logic in the class first
const prefetched = await AsyncLiteComponent.msg;

// ... and I haven't fully tested this but it should also be open for extension
class Extensior extends AsyncLiteComponent {
  constructor() {
    super();
    this.ready.then(() => console.log(this.msg))
  } 
}
const extendedwaittime = await new Extensior().ready;

在发帖之前，我在@slebetman的评论中对这种技术的可行性进行了简短的讨论。我并没有完全被这种直接的解雇所说服，所以我认为我应该进一步讨论/推翻它。请尽你最大的努力吧。