在你的UITableViewCell子类中，覆盖layoutSubviews并隐藏_UITableViewCellSeparatorView。适用于iOS 10。

override func layoutSubviews() {
    super.layoutSubviews()

    subviews.forEach { (view) in
        if view.dynamicType.description() == "_UITableViewCellSeparatorView" {
            view.hidden = true
        }
    }
}

在viewDidLoad中添加这一行:

self.tableView.separatorColor = [UIColor clearColor];

在cellForRowAtIndexPath中:

适用于iOS低版本

if(indexPath.row != self.newCarArray.count-1){
    UIImageView *line = [[UIImageView alloc] initWithFrame:CGRectMake(0, 44, 320, 2)];
    line.backgroundColor = [UIColor redColor];
    [cell addSubview:line];
}

适用于iOS 7以上版本(包括iOS 8)

if (indexPath.row == self.newCarArray.count-1) {
    cell.separatorInset = UIEdgeInsetsMake(0.f, cell.bounds.size.width, 0.f, 0.f);
}

迅速:

public func tableView(_ tableView: UITableView, cellForRowAt indexPath: IndexPath) -> UITableViewCell {

    ...

    // remove separator for last cell
    cell.separatorInset = indexPath.row < numberOfRowsInSection-1
        ? tableView.separatorInset
        : UIEdgeInsets(top: 0, left: tableView.bounds.size.width, bottom: 0, right: 0)

    return cell
}

objective - c:

- (UITableViewCell *)tableView:(UITableView *)tableView
     cellForRowAtIndexPath:(NSIndexPath *)indexPath {

    ...

    // remove separator for last cell
    cell.separatorInset = (indexPath.row < numberOfRowsInSection-1)
        ? tableView.separatorInset
        : UIEdgeInsetsMake(0.f, tableView.bounds.size.width, 0.f, 0.f);

    return cell;
}

试试下面的代码，也许能帮你解决问题

- (UITableViewCell *)tableView:(UITableView *)tableView cellForRowAtIndexPath:(NSIndexPath *)indexPath {

   NSString* reuseIdentifier = @"Contact Cell";

    UITableViewCell* cell = [tableView dequeueReusableCellWithIdentifier:reuseIdentifier];
    if (nil == cell) {
        cell = [[UITableViewCell alloc] initWithStyle:UITableViewCellStyleDefault reuseIdentifier:reuseIdentifier];
if (indexPath.row != 10) {//Specify the cell number
        cell.backgroundView.backgroundColor = [UIColor colorWithPatternImage:[UIImage imageNamed:@"bgWithLine.png"]];

} else {
        cell.backgroundView.backgroundColor = [UIColor colorWithPatternImage:[UIImage imageNamed:@"bgWithOutLine.png"]];

}

    }

    return cell;
}

  if([_data count] == 0 ){
       [self.tableView setSeparatorStyle:UITableViewCellSeparatorStyleNone];//  [self tableView].=YES;
    } else {
      [self.tableView setSeparatorStyle:UITableViewCellSeparatorStyleSingleLine];////    [self tableView].hidden=NO;
    }

我的开发环境是

Xcode 7.0 7A220 Swift 2.0 iOS 9.0

以上答案并不完全适用于我

经过尝试，我最终的工作解决方案是:

let indent_large_enought_to_hidden:CGFloat = 10000
cell.separatorInset = UIEdgeInsetsMake(0, indent_large_enought_to_hidden, 0, 0) // indent large engough for separator(including cell' content) to hidden separator
cell.indentationWidth = indent_large_enought_to_hidden * -1 // adjust the cell's content to show normally
cell.indentationLevel = 1 // must add this, otherwise default is 0, now actual indentation = indentationWidth * indentationLevel = 10000 * 1 = -10000

结果是: