你可以从标题标签层中删除动画:

    [[[theButton titleLabel] layer] removeAllAnimations];

你实际上可以在动画块之外设置标题，只是要确保在performWithoutAnimation中调用layoutIfNeeded():

button1.setTitle("abc", forState: .Normal)
button2.setTitle("abc", forState: .Normal)
button3.setTitle("abc", forState: .Normal)
UIView.performWithoutAnimation {
    self.button1.layoutIfNeeded()
    self.button2.layoutIfNeeded()
    self.button3.layoutIfNeeded()
}

如果你有一堆按钮，考虑在超视图上调用layoutIfNeeded():

button1.setTitle("abc", forState: .Normal)
button2.setTitle("abc", forState: .Normal)
button3.setTitle("abc", forState: .Normal)
UIView.performWithoutAnimation {
    self.view.layoutIfNeeded()
}

设置UIButton类型为自定义。这应该会删除淡入和淡出动画。

在Swift中，你可以使用:

UIView.performWithoutAnimation {
    self.someButtonButton.setTitle(newTitle, forState: .normal)
    self.someButtonButton.layoutIfNeeded()
}

结合以上的答案，可以为UIButtonTypeSystem提供以下解决方案:

if (_button.enabled)
{
    [UIView setAnimationsEnabled:NO];
    [_button setTitle:@"title" forState:UIControlStateNormal];
    [UIView setAnimationsEnabled:YES];
}
else // disabled
{
    [UIView setAnimationsEnabled:NO];
    _button.enabled = YES;
    [_button setTitle:@"title" forState:UIControlStateNormal];
    _button.enabled = NO;
    [UIView setAnimationsEnabled:YES];
}

Xhacker Liu扩展转换为Swift 3:

extension UIButton {
    func setTitleWithoutAnimation(title: String?) {
        UIView.setAnimationsEnabled(false)

        setTitle(title, for: .normal)

        layoutIfNeeded()
        UIView.setAnimationsEnabled(true)
    }
}