基于@tomvon，我完成了以下使用(选择你的案例):

a)调整高度(我知道新的宽度，所以我需要新的高度)

new_width  = 680
new_height = new_width * height / width 

b)调整宽度(我知道新的高度，所以我需要新的宽度)

new_height = 680
new_width  = new_height * width / height

然后:

img = img.resize((new_width, new_height), Image.ANTIALIAS)

我用这种方法调整了图像的大小，效果很好

from io import BytesIO
from django.core.files.uploadedfile import InMemoryUploadedFile
import os, sys
from PIL import Image


def imageResize(image):
    outputIoStream = BytesIO()
    imageTemproaryResized = imageTemproary.resize( (1920,1080), Image.ANTIALIAS) 
    imageTemproaryResized.save(outputIoStream , format='PNG', quality='10') 
    outputIoStream.seek(0)
    uploadedImage = InMemoryUploadedFile(outputIoStream,'ImageField', "%s.jpg" % image.name.split('.')[0], 'image/jpeg', sys.getsizeof(outputIoStream), None)

    ## For upload local folder
    fs = FileSystemStorage()
    filename = fs.save(uploadedImage.name, uploadedImage)

如果你试图保持相同的纵横比，那么你不会调整原始大小的一些百分比吗?

例如，原来大小的一半

half = 0.5
out = im.resize( [int(half * s) for s in im.size] )

举个丑陋的例子。

函数获取像pic[0-9a-z]这样的文件。[扩展]"，将它们调整为120x120，移动部分到中心，并保存到"ico[0-9a-z]。[扩展]”，肖像和风景作品:

def imageResize(filepath):
    from PIL import Image
    file_dir=os.path.split(filepath)
    img = Image.open(filepath)

    if img.size[0] > img.size[1]:
        aspect = img.size[1]/120
        new_size = (img.size[0]/aspect, 120)
    else:
        aspect = img.size[0]/120
        new_size = (120, img.size[1]/aspect)
    img.resize(new_size).save(file_dir[0]+'/ico'+file_dir[1][3:])
    img = Image.open(file_dir[0]+'/ico'+file_dir[1][3:])

    if img.size[0] > img.size[1]:
        new_img = img.crop( (
            (((img.size[0])-120)/2),
            0,
            120+(((img.size[0])-120)/2),
            120
        ) )
    else:
        new_img = img.crop( (
            0,
            (((img.size[1])-120)/2),
            120,
            120+(((img.size[1])-120)/2)
        ) )

    new_img.save(file_dir[0]+'/ico'+file_dir[1][3:])

已经更新了上面的答案“tomvon”

from PIL import Image

img = Image.open(image_path)

width, height = img.size[:2]

if height > width:
    baseheight = 64
    hpercent = (baseheight/float(img.size[1]))
    wsize = int((float(img.size[0])*float(hpercent)))
    img = img.resize((wsize, baseheight), Image.ANTIALIAS)
    img.save('resized.jpg')
else:
    basewidth = 64
    wpercent = (basewidth/float(img.size[0]))
    hsize = int((float(img.size[1])*float(wpercent)))
    img = img.resize((basewidth,hsize), Image.ANTIALIAS)
    img.save('resized.jpg')

这个脚本将使用PIL (Python成像库)将图像(somepic.jpg)调整为300像素的宽度和与新宽度成比例的高度。它通过确定300像素是原始宽度(img.size[0])的百分比，然后将原始高度(img.size[1])乘以该百分比来实现这一点。将“basewidth”更改为任何其他数字以更改图像的默认宽度。

from PIL import Image

basewidth = 300
img = Image.open('somepic.jpg')
wpercent = (basewidth/float(img.size[0]))
hsize = int((float(img.size[1])*float(wpercent)))
img = img.resize((basewidth,hsize), Image.Resampling.LANCZOS)
img.save('somepic.jpg')