免责声明:这个答案描述的是十年前的情况，当时pip还不支持二进制包。Conda是专门为更好地支持构建和分发二进制包而创建的，特别是带有C扩展的数据科学库。作为参考，pip只获得了带轮子的便携式二进制包的广泛支持(2013年的pip 1.4)和manylinux1规范(2016年3月的pip 8.1)。查看最近的答案了解更多历史。

以下是一个简短的概述:

pip

只支持Python包。 从源代码编译所有内容。编辑:pip现在安装二进制车轮，如果他们是可用的。 受到核心Python社区的支持(即Python 3.4+包含自动引导pip的代码)。

conda

Python agnostic. The main focus of existing packages are for Python, and indeed Conda itself is written in Python, but you can also have Conda packages for C libraries, or R packages, or really anything. Installs binaries. There is a tool called conda build that builds packages from source, but conda install itself installs things from already built Conda packages. External. conda is an environment and package manager. It is included in the Anaconda Python distribution provided by Continuum Analytics (now called Anaconda, Inc.).

conda is an environment manager written in Python and is language-agnostic. conda environment management functions cover the functionality provided by venv, virtualenv, pipenv, pyenv, and other Python-specific package managers. You could use conda within an existing Python installation by pip installing it (though this is not recommended unless you have a good reason to use an existing installation). As of 2022, conda and pip are not fully aware of one another package management activities within a virtual environment, not are they interoperable for Python package management.

在这两种情况下:

用Python编写 开源(conda是BSD, pip是MIT) 警告:虽然conda本身是开源的，但包存储库由Anaconda Inc托管，并且在商业使用方面有限制。

The first two bullet points of conda are really what make it advantageous over pip for many packages. Since pip installs from source, it can be painful to install things with it if you are unable to compile the source code (this is especially true on Windows, but it can even be true on Linux if the packages have some difficult C or FORTRAN library dependencies). conda installs from binary, meaning that someone (e.g., Continuum) has already done the hard work of compiling the package, and so the installation is easy.

如果您对构建自己的包感兴趣，也有一些不同之处。例如，pip构建在setuptools之上，而conda使用自己的格式，这有一些优点(比如是静态的，并且与Python无关)。

为了不让你们更困惑， 但是你也可以在conda环境中使用PIP，它会验证上面的一般管理器注释和特定于python的管理器注释。

conda install -n testenv pip
source activate testenv
pip <pip command>

您还可以将PIP添加到任何环境的默认包中，以便每次都显示它，这样您就不必遵循上面的代码段。

免责声明:这个答案描述的是十年前的情况，当时pip还不支持二进制包。Conda是专门为更好地支持构建和分发二进制包而创建的，特别是带有C扩展的数据科学库。作为参考，pip只获得了带轮子的便携式二进制包的广泛支持(2013年的pip 1.4)和manylinux1规范(2016年3月的pip 8.1)。查看最近的答案了解更多历史。

以下是一个简短的概述:

pip

只支持Python包。 从源代码编译所有内容。编辑:pip现在安装二进制车轮，如果他们是可用的。 受到核心Python社区的支持(即Python 3.4+包含自动引导pip的代码)。

conda

Python agnostic. The main focus of existing packages are for Python, and indeed Conda itself is written in Python, but you can also have Conda packages for C libraries, or R packages, or really anything. Installs binaries. There is a tool called conda build that builds packages from source, but conda install itself installs things from already built Conda packages. External. conda is an environment and package manager. It is included in the Anaconda Python distribution provided by Continuum Analytics (now called Anaconda, Inc.).

conda is an environment manager written in Python and is language-agnostic. conda environment management functions cover the functionality provided by venv, virtualenv, pipenv, pyenv, and other Python-specific package managers. You could use conda within an existing Python installation by pip installing it (though this is not recommended unless you have a good reason to use an existing installation). As of 2022, conda and pip are not fully aware of one another package management activities within a virtual environment, not are they interoperable for Python package management.

在这两种情况下:

用Python编写 开源(conda是BSD, pip是MIT) 警告:虽然conda本身是开源的，但包存储库由Anaconda Inc托管，并且在商业使用方面有限制。

The first two bullet points of conda are really what make it advantageous over pip for many packages. Since pip installs from source, it can be painful to install things with it if you are unable to compile the source code (this is especially true on Windows, but it can even be true on Linux if the packages have some difficult C or FORTRAN library dependencies). conda installs from binary, meaning that someone (e.g., Continuum) has already done the hard work of compiling the package, and so the installation is easy.

如果您对构建自己的包感兴趣，也有一些不同之处。例如，pip构建在setuptools之上，而conda使用自己的格式，这有一些优点(比如是静态的，并且与Python无关)。

其他答案对细节进行了合理的描述，但我想强调一些高级点。

PIP是一个包管理器，可以方便地安装、升级和卸载python包。它也适用于虚拟python环境。

Conda是任何软件(安装、升级和卸载)的包管理器。它还适用于虚拟系统环境。

conda设计的目标之一是方便用户所需的整个软件堆栈的包管理，其中一个或多个python版本可能只是一小部分。这包括低级库，如线性代数，编译器，如Windows上的mingw，编辑器，版本控制工具，如Hg和Git，或任何其他需要分发和管理的工具。

对于版本管理，pip允许您在多个python环境之间切换和管理。

Conda允许您在多个通用环境之间切换和管理，在这些环境中，许多其他东西的版本号可能不同，比如c库、编译器、测试套件或数据库引擎等等。

Conda不是以Windows为中心的，但在Windows上，当需要安装和管理需要编译的复杂科学包时，它是目前可用的最好的解决方案。

当我想到在Windows上通过pip编译许多这些包，或者在需要编译时调试失败的pip安装会话时，我浪费了多少时间，我想哭。

最后一点，Continuum Analytics还提供(免费的)binstar.org(现在叫anaconda.org)，允许常规的软件包开发人员创建他们自己的自定义(构建的!)软件堆栈，他们的软件包用户可以从中安装conda。

引用Conda for Data Science在Continuum网站上的文章:

Conda vs pip Python programmers are probably familiar with pip to download packages from PyPI and manage their requirements. Although, both conda and pip are package managers, they are very different: Pip is specific for Python packages and conda is language-agnostic, which means we can use conda to manage packages from any language Pip compiles from source and conda installs binaries, removing the burden of compilation Conda creates language-agnostic environments natively whereas pip relies on virtualenv to manage only Python environments Though it is recommended to always use conda packages, conda also includes pip, so you don’t have to choose between the two. For example, to install a python package that does not have a conda package, but is available through pip, just run, for example:

conda install pip
pip install gensim

I may have found one further difference of a minor nature. I have my python environments under /usr rather than /home or whatever. In order to install to it, I would have to use sudo install pip. For me, the undesired side effect of sudo install pip was slightly different than what are widely reported elsewhere: after doing so, I had to run python with sudo in order to import any of the sudo-installed packages. I gave up on that and eventually found I could use sudo conda to install packages to an environment under /usr which then imported normally without needing sudo permission for python. I even used sudo conda to fix a broken pip rather than using sudo pip uninstall pip or sudo pip --upgrade install pip.