我讨厌这里展示的任何完整的解决方案，我现在做了一个混合和测试，为任何事件处理程序工作:

public class MyMain()
    public void MyMethod() {
        AnotherClass.TheEventHandler += DoSomeThing;
    }

    private void DoSomething(object sender, EventArgs e) {
        Debug.WriteLine("I did something");
        AnotherClass.ClearAllDelegatesOfTheEventHandler();
    }

}

public static class AnotherClass {

    public static event EventHandler TheEventHandler;

    public static void ClearAllDelegatesOfTheEventHandler() {

        foreach (Delegate d in TheEventHandler.GetInvocationList())
        {
            TheEventHandler -= (EventHandler)d;
        }
    }
}

简单!感谢Stephen Punak。

我使用它是因为我使用一个通用的本地方法来删除委托，当设置不同的委托时，在不同的情况下调用本地方法。

你们对自己太苛刻了。很简单:

void OnFormClosing(object sender, FormClosingEventArgs e)
{
    foreach(Delegate d in FindClicked.GetInvocationList())
    {
        FindClicked -= (FindClickedHandler)d;
    }
}

我找到了这个答案，它几乎满足了我的需求。感谢SwDevMan81的课程。我已经修改了它，以允许抑制和恢复单个方法，我想我应该把它贴在这里。

// This class allows you to selectively suppress event handlers for controls.  You instantiate
// the suppressor object with the control, and after that you can use it to suppress all events
// or a single event.  If you try to suppress an event which has already been suppressed
// it will be ignored.  Same with resuming; you can resume all events which were suppressed,
// or a single one.  If you try to resume an un-suppressed event handler, it will be ignored.

//cEventSuppressor _supButton1 = null;
//private cEventSuppressor SupButton1 {
//    get {
//        if (_supButton1 == null) {
//            _supButton1 = new cEventSuppressor(this.button1);
//        }
//        return _supButton1;
//    }
//}
//private void button1_Click(object sender, EventArgs e) {
//    MessageBox.Show("Clicked!");
//}

//private void button2_Click(object sender, EventArgs e) {
//    SupButton1.Suppress("button1_Click");
//}

//private void button3_Click(object sender, EventArgs e) {
//    SupButton1.Resume("button1_Click");
//}
using System;
using System.Collections.Generic;
using System.Text;

using System.Reflection;
using System.Windows.Forms;
using System.ComponentModel;

namespace Crystal.Utilities {
    public class cEventSuppressor {
        Control _source;
        EventHandlerList _sourceEventHandlerList;
        FieldInfo _headFI;
        Dictionary<object, Delegate[]> suppressedHandlers = new Dictionary<object, Delegate[]>();
        PropertyInfo _sourceEventsInfo;
        Type _eventHandlerListType;
        Type _sourceType;

        public cEventSuppressor(Control control) {
            if (control == null)
                throw new ArgumentNullException("control", "An instance of a control must be provided.");

            _source = control;
            _sourceType = _source.GetType();
            _sourceEventsInfo = _sourceType.GetProperty("Events", BindingFlags.Instance | BindingFlags.NonPublic);
            _sourceEventHandlerList = (EventHandlerList)_sourceEventsInfo.GetValue(_source, null);
            _eventHandlerListType = _sourceEventHandlerList.GetType();
            _headFI = _eventHandlerListType.GetField("head", BindingFlags.Instance | BindingFlags.NonPublic);
        }
        private Dictionary<object, Delegate[]> BuildList() {
            Dictionary<object, Delegate[]> retval = new Dictionary<object, Delegate[]>();
            object head = _headFI.GetValue(_sourceEventHandlerList);
            if (head != null) {
                Type listEntryType = head.GetType();
                FieldInfo delegateFI = listEntryType.GetField("handler", BindingFlags.Instance | BindingFlags.NonPublic);
                FieldInfo keyFI = listEntryType.GetField("key", BindingFlags.Instance | BindingFlags.NonPublic);
                FieldInfo nextFI = listEntryType.GetField("next", BindingFlags.Instance | BindingFlags.NonPublic);
                retval = BuildListWalk(retval, head, delegateFI, keyFI, nextFI);
            }
            return retval;
        }

        private Dictionary<object, Delegate[]> BuildListWalk(Dictionary<object, Delegate[]> dict,
                                    object entry, FieldInfo delegateFI, FieldInfo keyFI, FieldInfo nextFI) {
            if (entry != null) {
                Delegate dele = (Delegate)delegateFI.GetValue(entry);
                object key = keyFI.GetValue(entry);
                object next = nextFI.GetValue(entry);

                if (dele != null) {
                    Delegate[] listeners = dele.GetInvocationList();
                    if (listeners != null && listeners.Length > 0) {
                        dict.Add(key, listeners);
                    }
                }
                if (next != null) {
                    dict = BuildListWalk(dict, next, delegateFI, keyFI, nextFI);
                }
            }
            return dict;
        }
        public void Resume() {
        }
        public void Resume(string pMethodName) {
            //if (_handlers == null)
            //    throw new ApplicationException("Events have not been suppressed.");
            Dictionary<object, Delegate[]> toRemove = new Dictionary<object, Delegate[]>();

            // goes through all handlers which have been suppressed.  If we are resuming,
            // all handlers, or if we find the matching handler, add it back to the
            // control's event handlers
            foreach (KeyValuePair<object, Delegate[]> pair in suppressedHandlers) {

                for (int x = 0; x < pair.Value.Length; x++) {

                    string methodName = pair.Value[x].Method.Name;
                    if (pMethodName == null || methodName.Equals(pMethodName)) {
                        _sourceEventHandlerList.AddHandler(pair.Key, pair.Value[x]);
                        toRemove.Add(pair.Key, pair.Value);
                    }
                }
            }
            // remove all un-suppressed handlers from the list of suppressed handlers
            foreach (KeyValuePair<object, Delegate[]> pair in toRemove) {
                for (int x = 0; x < pair.Value.Length; x++) {
                    suppressedHandlers.Remove(pair.Key);
                }
            }
            //_handlers = null;
        }
        public void Suppress() {
            Suppress(null);
        }
        public void Suppress(string pMethodName) {
            //if (_handlers != null)
            //    throw new ApplicationException("Events are already being suppressed.");

            Dictionary<object, Delegate[]> dict = BuildList();

            foreach (KeyValuePair<object, Delegate[]> pair in dict) {
                for (int x = pair.Value.Length - 1; x >= 0; x--) {
                    //MethodInfo mi = pair.Value[x].Method;
                    //string s1 = mi.Name; // name of the method
                    //object o = pair.Value[x].Target;
                    // can use this to invoke method    pair.Value[x].DynamicInvoke
                    string methodName = pair.Value[x].Method.Name;

                    if (pMethodName == null || methodName.Equals(pMethodName)) {
                        _sourceEventHandlerList.RemoveHandler(pair.Key, pair.Value[x]);
                        suppressedHandlers.Add(pair.Key, pair.Value);
                    }
                }
            }
        }
    } 
}

接受的答案不完整。对于声明为{add;删除;}

下面是工作代码:

public static void ClearEventInvocations(this object obj, string eventName)
{
    var fi = obj.GetType().GetEventField(eventName);
    if (fi == null) return;
    fi.SetValue(obj, null);
}

private static FieldInfo GetEventField(this Type type, string eventName)
{
    FieldInfo field = null;
    while (type != null)
    {
        /* Find events defined as field */
        field = type.GetField(eventName, BindingFlags.Static | BindingFlags.Instance | BindingFlags.NonPublic);
        if (field != null && (field.FieldType == typeof(MulticastDelegate) || field.FieldType.IsSubclassOf(typeof(MulticastDelegate))))
            break;

        /* Find events defined as property { add; remove; } */
        field = type.GetField("EVENT_" + eventName.ToUpper(), BindingFlags.Static | BindingFlags.Instance | BindingFlags.NonPublic);
        if (field != null)
            break;
        type = type.BaseType;
    }
    return field;
}

虽然有点晚了，但我使用了这个对我来说非常有效的链接: https://www.codeproject.com/Articles/103542/Removing-Event-Handlers-using-Reflection

这个代码的美妙之处在于它适用于所有人，WFP, Forms, Xamarin Forms。我用它来做沙玛林。请注意，只有当你不拥有这个事件(例如，一个库代码在你不关心的一些事件上崩溃)时，你才需要这种方式使用Reflection。

下面是我稍微修改过的代码:

    static Dictionary<Type, List<FieldInfo>> dicEventFieldInfos = new Dictionary<Type, List<FieldInfo>>();

    static BindingFlags AllBindings
    {
        get { return BindingFlags.IgnoreCase | BindingFlags.Public | BindingFlags.NonPublic | BindingFlags.Instance | BindingFlags.Static; }
    }

    static void BuildEventFields(Type t, List<FieldInfo> lst)
    {
        foreach (EventInfo ei in t.GetEvents(AllBindings))
        {
            Type dt = ei.DeclaringType;
            FieldInfo fi = dt.GetField(ei.Name, AllBindings);
            if (fi != null)
                lst.Add(fi);
        }
    }
    static List<FieldInfo> GetTypeEventFields(Type t)
    {
        if (dicEventFieldInfos.ContainsKey(t))
            return dicEventFieldInfos[t];

        List<FieldInfo> lst = new List<FieldInfo>();
        BuildEventFields(t, lst);
        dicEventFieldInfos.Add(t, lst);
        return lst;
    }
    static EventHandlerList GetStaticEventHandlerList(Type t, object obj)
    {
        MethodInfo mi = t.GetMethod("get_Events", AllBindings);
        return (EventHandlerList)mi.Invoke(obj, new object[] { });
    }
    public static void RemoveEventHandler(object obj, string EventName = "")
    {
        if (obj == null)
            return;

        Type t = obj.GetType();
        List<FieldInfo> event_fields = GetTypeEventFields(t);
        EventHandlerList static_event_handlers = null;

        foreach (FieldInfo fi in event_fields)
        {
            if (EventName != "" && string.Compare(EventName, fi.Name, true) != 0)
                continue;
            var eventName = fi.Name;
            // After hours and hours of research and trial and error, it turns out that
            // STATIC Events have to be treated differently from INSTANCE Events...
            if (fi.IsStatic)
            {
                // STATIC EVENT
                if (static_event_handlers == null)
                    static_event_handlers = GetStaticEventHandlerList(t, obj);

                object idx = fi.GetValue(obj);
                Delegate eh = static_event_handlers[idx];
                if (eh == null)
                    continue;

                Delegate[] dels = eh.GetInvocationList();
                if (dels == null)
                    continue;

                EventInfo ei = t.GetEvent(eventName, AllBindings);
                foreach (Delegate del in dels)
                    ei.RemoveEventHandler(obj, del);
            }
            else
            {
                // INSTANCE EVENT
                EventInfo ei = t.GetEvent(eventName, AllBindings);
                if (ei != null)
                {
                    object val = fi.GetValue(obj);
                    Delegate mdel = (val as Delegate);
                    if (mdel != null)
                    {
                        foreach (Delegate del in mdel.GetInvocationList())
                        {
                            ei.RemoveEventHandler(obj, del);
                        }
                    }
                }
            }
        }
    }

示例用法:RemoveEventHandler(obj， "Focused");

这不是对OP的回答，但我想我把它贴在这里，以防它能帮助到其他人。

  /// <summary>
  /// Method to remove a (single) SocketAsyncEventArgs.Completed event handler. This is 
  /// partially based on information found here: http://stackoverflow.com/a/91853/253938
  /// 
  /// But note that this may not be a good idea, being very .Net implementation-dependent. Note 
  /// in particular use of "m_Completed" instead of "Completed".
  /// </summary>
  private static void RemoveCompletedEventHandler(SocketAsyncEventArgs eventArgs)
  {
     FieldInfo fieldInfo = typeof(SocketAsyncEventArgs).GetField("m_Completed", 
                                                BindingFlags.Instance | BindingFlags.NonPublic);
     eventArgs.Completed -= (EventHandler<SocketAsyncEventArgs>)fieldInfo.GetValue(eventArgs);
  }