Wheat的答案很好，但它假设您在任何模式或数据库中都没有任何相同的表名/列名对。为了确保安全，使用这个。。。

select *
from Information_Schema.Columns
where Table_Catalog = 'DatabaseName'
  and Table_Schema = 'SchemaName'
  and Table_Name = 'TableName'
  and Column_Name = 'ColumnName'

declare @myColumn   as nvarchar(128)
set @myColumn = 'myColumn'
if not exists (
    select  1
    from    information_schema.columns columns 
    where   columns.table_catalog   = 'myDatabase'
        and columns.table_schema    = 'mySchema' 
        and columns.table_name      = 'myTable' 
        and columns.column_name     = @myColumn
    )
begin
    exec('alter table myDatabase.mySchema.myTable add'
    +'    ['+@myColumn+'] bigint       null')
end

IF NOT EXISTS(SELECT NULL
              FROM  INFORMATION_SCHEMA.COLUMNS
              WHERE table_name = 'TableName'
                    AND table_schema = 'SchemaName'
                    AND column_name = 'ColumnName') BEGIN

  ALTER TABLE [SchemaName].[TableName] ADD [ColumnName] int(1) NOT NULL default '0';

END;

IF EXISTS (
SELECT *
FROM INFORMATION_SCHEMA.COLUMNS
WHERE TABLE_CATALOG = 'Database Name'
and TABLE_SCHEMA = 'Schema Name'
and TABLE_NAME = 'Table Name'
and COLUMN_NAME = 'Column Name'
and DATA_TYPE = 'Column Type') -- Where statement lines can be deleted.

BEGIN
  -- Column exists in table
END

ELSE BEGIN
  -- Column does not exist in table
END

还有一种变化。。。

SELECT 
  Count(*) AS existFlag 
FROM 
  sys.columns 
WHERE 
  [name] = N 'ColumnName' 
  AND [object_id] = OBJECT_ID(N 'TableName')

试试这个。。。

IF NOT EXISTS(
  SELECT TOP 1 1
  FROM INFORMATION_SCHEMA.COLUMNS
  WHERE 
    [TABLE_NAME] = 'Employees'
    AND [COLUMN_NAME] = 'EmployeeID')
BEGIN
  ALTER TABLE [Employees]
    ADD [EmployeeID] INT NULL
END