其他人已经提到了圆括号方法，但我想补充一点，使用圆括号时，允许内联注释。

对每个片段的注释：

nursery_rhyme = (
    'Mary had a little lamb,'          # Comments are great!
    'its fleece was white as snow.'
    'And everywhere that Mary went,'
    'her sheep would surely go.'       # What a pesky sheep.
)

继续后不允许注释：

使用反斜杠行延续符（\）时，不允许使用注释。您将收到一个SyntaxError：一行接一行的连续字符错误。

nursery_rhyme = 'Mary had a little lamb,' \  # These comments
    'its fleece was white as snow.'       \  # are invalid!
    'And everywhere that Mary went,'      \
    'her sheep would surely go.'
# => SyntaxError: unexpected character after line continuation character

Regex字符串的更好注释：

基于以下示例https://docs.python.org/3/library/re.html#re.VERBOSE,

a = re.compile(
    r'\d+'  # the integral part
    r'\.'   # the decimal point
    r'\d*'  # some fractional digits
)

# Using VERBOSE flag, IDE usually can't syntax highight the string comment.
a = re.compile(r"""\d +  # the integral part
                   \.    # the decimal point
                   \d *  # some fractional digits""", re.X)

用\换行对我很有用。下面是一个例子：

longStr = "This is a very long string " \
        "that I wrote to help somebody " \
        "who had a question about " \
        "writing long strings in Python"

您还可以将SQL语句放置在单独的文件action.SQL中，并使用以下命令将其加载到.py文件中：

with open('action.sql') as f:
   query = f.read()

因此，SQL语句将与Python代码分离。如果SQL语句中有需要从Python填充的参数，则可以使用字符串格式（如%s或｛field｝）。

在Python>=3.6中，可以使用格式化字符串文本（f字符串）

query= f'''SELECT   action.descr as "action"
    role.id as role_id,
    role.descr as role
    FROM
    public.role_action_def,
    public.role,
    public.record_def,
    public.action
    WHERE role.id = role_action_def.role_id AND
    record_def.id = role_action_def.def_id AND
    action.id = role_action_def.action_id AND
    role_action_def.account_id = {account_id} AND
    record_def.account_id = {account_id} AND
    def_id = {def_id}'''

我认为当代码（例如，变量）缩进并且输出字符串应该是单行（没有换行）时，另一个选项更可读：

def some_method():

    long_string = """
A presumptuous long string
which looks a bit nicer
in a text editor when
written over multiple lines
""".strip('\n').replace('\n', ' ')

    return long_string

我发现自己对这个很满意：

string = """This is a
very long string,
containing commas,
that I split up
for readability""".replace('\n',' ')