结合以下观点：

Levon或Jesse、Faheel和ddrscott

根据我的格式建议，您可以将查询写成：

query = ('SELECT'
             ' action.descr as "action"'
             ',role.id as role_id'
             ',role.descr as role'
         ' FROM'
             ' public.role_action_def'
             ',public.role'
             ',public.record_def'
             ',public.action'
         ' WHERE'
             ' role.id = role_action_def.role_id'
             ' AND'
             ' record_def.id = role_action_def.def_id'
             ' AND'
             ' action.id = role_action_def.action_id'
             ' AND'
             ' role_action_def.account_id = ?' # account_id
             ' AND'
             ' record_def.account_id = ?'      # account_id
             ' AND'
             ' def_id = ?'                     # def_id
         )

 vars = (account_id, account_id, def_id)     # A tuple of the query variables
 cursor.execute(query, vars)                 # Using Python's sqlite3 module

或类似：

vars = []
query = ('SELECT'
             ' action.descr as "action"'
             ',role.id as role_id'
             ',role.descr as role'
         ' FROM'
             ' public.role_action_def'
             ',public.role'
             ',public.record_def'
             ',public.action'
         ' WHERE'
             ' role.id = role_action_def.role_id'
             ' AND'
             ' record_def.id = role_action_def.def_id'
             ' AND'
             ' action.id = role_action_def.action_id'
             ' AND'
             ' role_action_def.account_id = '
                 vars.append(account_id) or '?'
             ' AND'
             ' record_def.account_id = '
                 vars.append(account_id) or '?'
             ' AND'
             ' def_id = '
                 vars.append(def_id) or '?'
         )

 cursor.execute(query, tuple(vars))  # Using Python's sqlite3 module

与“IN”和“vars.extend（options）”或“n_options（len（option））”一起使用可能很有趣，其中：

def n_options(count):
    return '(' + ','.join(count*'?') + ')'

或者从darkcaline那里得到的提示是，您可能仍然会在使用前导空格和分隔符以及命名占位符时出错：

SPACE_SEP = ' '
COMMA_SEP = ', '
AND_SEP   = ' AND '

query = SPACE_SEP.join((
    'SELECT',
        COMMA_SEP.join((
        'action.descr as "action"',
        'role.id as role_id',
        'role.descr as role',
        )),
    'FROM',
        COMMA_SEP.join((
        'public.role_action_def',
        'public.role',
        'public.record_def',
        'public.action',
        )),
    'WHERE',
        AND_SEP.join((
        'role.id = role_action_def.role_id',
        'record_def.id = role_action_def.def_id',
        'action.id = role_action_def.action_id',
        'role_action_def.account_id = :account_id',
        'record_def.account_id = :account_id',
        'def_id = :def_id',
        )),
    ))

vars = {'account_id':account_id,'def_id':def_id}  # A dictionary of the query variables
cursor.execute(query, vars)                       # Using Python's sqlite3 module

请参阅Cursor.execute-function的文档。

“这是[最Python]的方式！”-。。。

在Python>=3.6中，可以使用格式化字符串文本（f字符串）

query= f'''SELECT   action.descr as "action"
    role.id as role_id,
    role.descr as role
    FROM
    public.role_action_def,
    public.role,
    public.record_def,
    public.action
    WHERE role.id = role_action_def.role_id AND
    record_def.id = role_action_def.def_id AND
    action.id = role_action_def.action_id AND
    role_action_def.account_id = {account_id} AND
    record_def.account_id = {account_id} AND
    def_id = {def_id}'''

你的实际代码不应该工作；在“行”的末尾缺少空格（例如，role.descr作为roleFROM…）。

多行字符串有三个引号：

string = """line
  line2
  line3"""

它将包含换行符和额外的空格，但对于SQL来说这不是问题。

你说的是多行字符串吗？简单，使用三引号开始和结束它们。

s = """ this is a very
        long string if I had the
        energy to type more and more ..."""

您也可以使用单引号（当然，在开始和结束处有3个引号），并像对待任何其他字符串一样对待生成的字符串。

注意：与任何字符串一样，起始引号和结束引号之间的任何内容都将成为字符串的一部分，因此本示例有一个前导空格（如@root45所指出的）。此字符串还将包含空格和换行符。

即。，：

' this is a very\n        long string if I had the\n        energy to type more and more ...'

最后，您还可以在Python中构造如下的长行：

 s = ("this is a very"
      "long string too"
      "for sure ..."
     )

这将不包括任何额外的空格或换行符（这是一个故意的示例，显示跳过空格的效果）：

'this is a verylong string toofor sure ...'

不需要逗号，只需将要连接在一起的字符串放入一对括号中，并确保考虑到任何需要的空格和换行符。

您还可以将SQL语句放置在单独的文件action.SQL中，并使用以下命令将其加载到.py文件中：

with open('action.sql') as f:
   query = f.read()

因此，SQL语句将与Python代码分离。如果SQL语句中有需要从Python填充的参数，则可以使用字符串格式（如%s或｛field｝）。

其他人已经提到了圆括号方法，但我想补充一点，使用圆括号时，允许内联注释。

对每个片段的注释：

nursery_rhyme = (
    'Mary had a little lamb,'          # Comments are great!
    'its fleece was white as snow.'
    'And everywhere that Mary went,'
    'her sheep would surely go.'       # What a pesky sheep.
)

继续后不允许注释：

使用反斜杠行延续符（\）时，不允许使用注释。您将收到一个SyntaxError：一行接一行的连续字符错误。

nursery_rhyme = 'Mary had a little lamb,' \  # These comments
    'its fleece was white as snow.'       \  # are invalid!
    'And everywhere that Mary went,'      \
    'her sheep would surely go.'
# => SyntaxError: unexpected character after line continuation character

Regex字符串的更好注释：

基于以下示例https://docs.python.org/3/library/re.html#re.VERBOSE,

a = re.compile(
    r'\d+'  # the integral part
    r'\.'   # the decimal point
    r'\d*'  # some fractional digits
)

# Using VERBOSE flag, IDE usually can't syntax highight the string comment.
a = re.compile(r"""\d +  # the integral part
                   \.    # the decimal point
                   \d *  # some fractional digits""", re.X)