我以前也遇到过类似的问题。也许http://cronus.readthedocs.org会有帮助?

对于v0.2，下面的代码片段可以工作

import cronus.beat as beat

beat.set_rate(2) # run twice per second
while beat.true():
    # do some time consuming work here
    beat.sleep() # total loop duration would be 0.5 sec

    ''' tracking number of times it prints'''
import threading

global timeInterval
count=0
def printit():
  threading.Timer(timeInterval, printit).start()
  print( "Hello, World!")
  global count
  count=count+1
  print(count)
printit

if __name__ == "__main__":
    timeInterval= int(input('Enter Time in Seconds:'))
    printit()

你可能会考虑Twisted，它是一个实现了Reactor Pattern的Python网络库。

from twisted.internet import task, reactor

timeout = 60.0 # Sixty seconds

def doWork():
    #do work here
    pass

l = task.LoopingCall(doWork)
l.start(timeout) # call every sixty seconds

reactor.run()

虽然“While True: sleep(60)”可能会工作，Twisted可能已经实现了许多你最终需要的功能(如bobince指出的守护进程化、日志记录或异常处理)，并且可能是一个更健壮的解决方案

以下是MestreLion代码的改编版本。 除了原来的函数，这段代码:

1)添加用于在特定时间触发计时器的first_interval(调用者需要计算first_interval并传递进来)

2)在原代码中解决一个竞态条件。在原始代码中，如果控制线程未能取消正在运行的计时器(“停止计时器，并取消计时器动作的执行。这只会在计时器仍处于等待阶段时起作用。”引用自https://docs.python.org/2/library/threading.html)，计时器将无休止地运行。

class RepeatedTimer(object):
def __init__(self, first_interval, interval, func, *args, **kwargs):
    self.timer      = None
    self.first_interval = first_interval
    self.interval   = interval
    self.func   = func
    self.args       = args
    self.kwargs     = kwargs
    self.running = False
    self.is_started = False

def first_start(self):
    try:
        # no race-condition here because only control thread will call this method
        # if already started will not start again
        if not self.is_started:
            self.is_started = True
            self.timer = Timer(self.first_interval, self.run)
            self.running = True
            self.timer.start()
    except Exception as e:
        log_print(syslog.LOG_ERR, "timer first_start failed %s %s"%(e.message, traceback.format_exc()))
        raise

def run(self):
    # if not stopped start again
    if self.running:
        self.timer = Timer(self.interval, self.run)
        self.timer.start()
    self.func(*self.args, **self.kwargs)

def stop(self):
    # cancel current timer in case failed it's still OK
    # if already stopped doesn't matter to stop again
    if self.timer:
        self.timer.cancel()
    self.running = False

下面是MestreLion对代码的更新，它可以避免随着时间的推移而漂移。

这里的RepeatedTimer类按照OP的请求每隔“间隔”秒调用给定函数;调度并不取决于函数执行的时间。我喜欢这个解决方案，因为它没有外部库依赖关系;这是纯python。

import threading 
import time

class RepeatedTimer(object):
  def __init__(self, interval, function, *args, **kwargs):
    self._timer = None
    self.interval = interval
    self.function = function
    self.args = args
    self.kwargs = kwargs
    self.is_running = False
    self.next_call = time.time()
    self.start()

  def _run(self):
    self.is_running = False
    self.start()
    self.function(*self.args, **self.kwargs)

  def start(self):
    if not self.is_running:
      self.next_call += self.interval
      self._timer = threading.Timer(self.next_call - time.time(), self._run)
      self._timer.start()
      self.is_running = True

  def stop(self):
    self._timer.cancel()
    self.is_running = False

示例用法(摘自MestreLion的回答):

from time import sleep

def hello(name):
    print "Hello %s!" % name

print "starting..."
rt = RepeatedTimer(1, hello, "World") # it auto-starts, no need of rt.start()
try:
    sleep(5) # your long-running job goes here...
finally:
    rt.stop() # better in a try/finally block to make sure the program ends!

如果你想要一种非阻塞的方式来周期性地执行你的函数，而不是阻塞无限循环，我会使用线程计时器。这样，您的代码可以继续运行并执行其他任务，并且仍然每n秒调用一次您的函数。我经常使用这种技术打印长时间、CPU/磁盘/网络密集型任务的进度信息。

下面是我在类似问题中发布的代码，带有start()和stop()控件:

from threading import Timer

class RepeatedTimer(object):
    def __init__(self, interval, function, *args, **kwargs):
        self._timer     = None
        self.interval   = interval
        self.function   = function
        self.args       = args
        self.kwargs     = kwargs
        self.is_running = False
        self.start()

    def _run(self):
        self.is_running = False
        self.start()
        self.function(*self.args, **self.kwargs)

    def start(self):
        if not self.is_running:
            self._timer = Timer(self.interval, self._run)
            self._timer.start()
            self.is_running = True

    def stop(self):
        self._timer.cancel()
        self.is_running = False

用法:

from time import sleep

def hello(name):
    print "Hello %s!" % name

print "starting..."
rt = RepeatedTimer(1, hello, "World") # it auto-starts, no need of rt.start()
try:
    sleep(5) # your long-running job goes here...
finally:
    rt.stop() # better in a try/finally block to make sure the program ends!

特点:

只有标准库，没有外部依赖 即使计时器已经启动/停止，也可以安全地多次调用Start()和stop() 要调用的函数可以有位置参数和命名参数 您可以随时更改间隔，它将在下次运行后生效。args、kwargs甚至function也一样!