在类unix系统和Python 3.5+上有os。Set_blocking，做的就是它所说的。

import os
import time
import subprocess

cmd = 'python3', '-c', 'import time; [(print(i), time.sleep(1)) for i in range(5)]'
p = subprocess.Popen(cmd, stdout=subprocess.PIPE)
os.set_blocking(p.stdout.fileno(), False)
start = time.time()
while True:
    # first iteration always produces empty byte string in non-blocking mode
    for i in range(2):    
        line = p.stdout.readline()
        print(i, line)
        time.sleep(0.5)
    if time.time() > start + 5:
        break
p.terminate()

这个输出:

1 b''
2 b'0\n'
1 b''
2 b'1\n'
1 b''
2 b'2\n'
1 b''
2 b'3\n'
1 b''
2 b'4\n'

与操作系统。Set_blocking注释它是:

0 b'0\n'
1 b'1\n'
0 b'2\n'
1 b'3\n'
0 b'4\n'
1 b''

这是一个在子进程中执行交互命令的例子，通过伪终端实现了stdout的交互。您可以参考:https://stackoverflow.com/a/43012138/3555925

#!/usr/bin/env python
# -*- coding: utf-8 -*-

import os
import sys
import select
import termios
import tty
import pty
from subprocess import Popen

command = 'bash'
# command = 'docker run -it --rm centos /bin/bash'.split()

# save original tty setting then set it to raw mode
old_tty = termios.tcgetattr(sys.stdin)
tty.setraw(sys.stdin.fileno())

# open pseudo-terminal to interact with subprocess
master_fd, slave_fd = pty.openpty()

# use os.setsid() make it run in a new process group, or bash job control will not be enabled
p = Popen(command,
          preexec_fn=os.setsid,
          stdin=slave_fd,
          stdout=slave_fd,
          stderr=slave_fd,
          universal_newlines=True)

while p.poll() is None:
    r, w, e = select.select([sys.stdin, master_fd], [], [])
    if sys.stdin in r:
        d = os.read(sys.stdin.fileno(), 10240)
        os.write(master_fd, d)
    elif master_fd in r:
        o = os.read(master_fd, 10240)
        if o:
            os.write(sys.stdout.fileno(), o)

# restore tty settings back
termios.tcsetattr(sys.stdin, termios.TCSADRAIN, old_tty)

在这里添加这个答案，因为它提供了在Windows和Unix上设置非阻塞管道的能力。

所有的ctypes细节都要感谢@techtonik的回答。

有一个稍微修改过的版本，可以在Unix和Windows系统上使用。

兼容Python3(只需要一些小的修改)。 包括posix版本，并定义了用于这两个版本的异常。

这样你就可以在Unix和Windows代码中使用相同的函数和异常。

# pipe_non_blocking.py (module)
"""
Example use:

    p = subprocess.Popen(
            command,
            stdout=subprocess.PIPE,
            )

    pipe_non_blocking_set(p.stdout.fileno())

    try:
        data = os.read(p.stdout.fileno(), 1)
    except PortableBlockingIOError as ex:
        if not pipe_non_blocking_is_error_blocking(ex):
            raise ex
"""


__all__ = (
    "pipe_non_blocking_set",
    "pipe_non_blocking_is_error_blocking",
    "PortableBlockingIOError",
    )

import os


if os.name == "nt":
    def pipe_non_blocking_set(fd):
        # Constant could define globally but avoid polluting the name-space
        # thanks to: https://stackoverflow.com/questions/34504970
        import msvcrt

        from ctypes import windll, byref, wintypes, WinError, POINTER
        from ctypes.wintypes import HANDLE, DWORD, BOOL

        LPDWORD = POINTER(DWORD)

        PIPE_NOWAIT = wintypes.DWORD(0x00000001)

        def pipe_no_wait(pipefd):
            SetNamedPipeHandleState = windll.kernel32.SetNamedPipeHandleState
            SetNamedPipeHandleState.argtypes = [HANDLE, LPDWORD, LPDWORD, LPDWORD]
            SetNamedPipeHandleState.restype = BOOL

            h = msvcrt.get_osfhandle(pipefd)

            res = windll.kernel32.SetNamedPipeHandleState(h, byref(PIPE_NOWAIT), None, None)
            if res == 0:
                print(WinError())
                return False
            return True

        return pipe_no_wait(fd)

    def pipe_non_blocking_is_error_blocking(ex):
        if not isinstance(ex, PortableBlockingIOError):
            return False
        from ctypes import GetLastError
        ERROR_NO_DATA = 232

        return (GetLastError() == ERROR_NO_DATA)

    PortableBlockingIOError = OSError
else:
    def pipe_non_blocking_set(fd):
        import fcntl
        fl = fcntl.fcntl(fd, fcntl.F_GETFL)
        fcntl.fcntl(fd, fcntl.F_SETFL, fl | os.O_NONBLOCK)
        return True

    def pipe_non_blocking_is_error_blocking(ex):
        if not isinstance(ex, PortableBlockingIOError):
            return False
        return True

    PortableBlockingIOError = BlockingIOError

为了避免读取不完整的数据，我最终编写了自己的readline生成器(它为每一行返回字节字符串)。

它是一个发电机，所以你可以例如…

def non_blocking_readlines(f, chunk=1024):
    """
    Iterate over lines, yielding b'' when nothings left
    or when new data is not yet available.

    stdout_iter = iter(non_blocking_readlines(process.stdout))

    line = next(stdout_iter)  # will be a line or b''.
    """
    import os

    from .pipe_non_blocking import (
            pipe_non_blocking_set,
            pipe_non_blocking_is_error_blocking,
            PortableBlockingIOError,
            )

    fd = f.fileno()
    pipe_non_blocking_set(fd)

    blocks = []

    while True:
        try:
            data = os.read(fd, chunk)
            if not data:
                # case were reading finishes with no trailing newline
                yield b''.join(blocks)
                blocks.clear()
        except PortableBlockingIOError as ex:
            if not pipe_non_blocking_is_error_blocking(ex):
                raise ex

            yield b''
            continue

        while True:
            n = data.find(b'\n')
            if n == -1:
                break

            yield b''.join(blocks) + data[:n + 1]
            data = data[n + 1:]
            blocks.clear()
        blocks.append(data)

You can do this really easily in Twisted. Depending upon your existing code base, this might not be that easy to use, but if you are building a twisted application, then things like this become almost trivial. You create a ProcessProtocol class, and override the outReceived() method. Twisted (depending upon the reactor used) is usually just a big select() loop with callbacks installed to handle data from different file descriptors (often network sockets). So the outReceived() method is simply installing a callback for handling data coming from STDOUT. A simple example demonstrating this behavior is as follows:

from twisted.internet import protocol, reactor

class MyProcessProtocol(protocol.ProcessProtocol):

    def outReceived(self, data):
        print data

proc = MyProcessProtocol()
reactor.spawnProcess(proc, './myprogram', ['./myprogram', 'arg1', 'arg2', 'arg3'])
reactor.run()

Twisted文档在这方面有一些很好的信息。

如果您围绕Twisted构建整个应用程序，它可以与其他进程(本地或远程)进行异步通信，就像这样非常优雅。另一方面，如果您的程序不是构建在Twisted之上，那么这真的不会有多大帮助。希望这能对其他读者有所帮助，即使它不适用于您的特定应用程序。

编辑:这个实现仍然会阻塞。请用j·f·塞巴斯蒂安的答案。

我尝试了上面的答案，但是线程代码的额外风险和维护令人担忧。

通过io模块(仅限于2.6)，我找到了BufferedReader。这是我的无线程、无阻塞的解决方案。

import io
from subprocess import PIPE, Popen

p = Popen(['myprogram.exe'], stdout=PIPE)

SLEEP_DELAY = 0.001

# Create an io.BufferedReader on the file descriptor for stdout
with io.open(p.stdout.fileno(), 'rb', closefd=False) as buffer:
  while p.poll() == None:
      time.sleep(SLEEP_DELAY)
      while '\n' in bufferedStdout.peek(bufferedStdout.buffer_size):
          line = buffer.readline()
          # do stuff with the line

  # Handle any remaining output after the process has ended
  while buffer.peek():
    line = buffer.readline()
    # do stuff with the line

根据J.F. Sebastian的答案和其他几个来源，我组合了一个简单的子流程管理器。它提供了请求的非阻塞读取，以及并行运行几个进程。它不使用任何特定于操作系统的调用(我知道)，因此应该在任何地方工作。

它可以从pypi获得，所以只需pip安装shelljob。参考项目页面的示例和完整的文档。