我知道这是一个相当老的帖子。我采取了@SashaB给出的解决方案，并根据我的需要进行了修改。

我添加了以下内容:

字段忽略列表:序列化时要忽略的字段列表 字段替换列表:包含在序列化时要被值替换的字段名的字典。 删除方法和BaseQuery被序列化

我的代码如下:

def alchemy_json_encoder(revisit_self = False, fields_to_expand = [], fields_to_ignore = [], fields_to_replace = {}):
   """
   Serialize SQLAlchemy result into JSon
   :param revisit_self: True / False
   :param fields_to_expand: Fields which are to be expanded for including their children and all
   :param fields_to_ignore: Fields to be ignored while encoding
   :param fields_to_replace: Field keys to be replaced by values assigned in dictionary
   :return: Json serialized SQLAlchemy object
   """
   _visited_objs = []
   class AlchemyEncoder(json.JSONEncoder):
      def default(self, obj):
        if isinstance(obj.__class__, DeclarativeMeta):
            # don't re-visit self
            if revisit_self:
                if obj in _visited_objs:
                    return None
                _visited_objs.append(obj)

            # go through each field in this SQLalchemy class
            fields = {}
            for field in [x for x in dir(obj) if not x.startswith('_') and x != 'metadata' and x not in fields_to_ignore]:
                val = obj.__getattribute__(field)
                # is this field method defination, or an SQLalchemy object
                if not hasattr(val, "__call__") and not isinstance(val, BaseQuery):
                    field_name = fields_to_replace[field] if field in fields_to_replace else field
                    # is this field another SQLalchemy object, or a list of SQLalchemy objects?
                    if isinstance(val.__class__, DeclarativeMeta) or \
                            (isinstance(val, list) and len(val) > 0 and isinstance(val[0].__class__, DeclarativeMeta)):
                        # unless we're expanding this field, stop here
                        if field not in fields_to_expand:
                            # not expanding this field: set it to None and continue
                            fields[field_name] = None
                            continue

                    fields[field_name] = val
            # a json-encodable dict
            return fields

        return json.JSONEncoder.default(self, obj)
   return AlchemyEncoder

希望它能帮助到一些人!

虽然这是一篇老文章，也许我没有回答上面的问题，但我想谈谈我的连载，至少它对我有用。

我使用FastAPI,SqlAlchemy和MySQL，但我不使用orm模型;

# from sqlalchemy import create_engine
# from sqlalchemy.orm import sessionmaker
# engine = create_engine(config.SQLALCHEMY_DATABASE_URL, pool_pre_ping=True)
# SessionLocal = sessionmaker(autocommit=False, autoflush=False, bind=engine)

序列化代码

import decimal
import datetime


def alchemy_encoder(obj):
    """JSON encoder function for SQLAlchemy special classes."""
    if isinstance(obj, datetime.date):
        return obj.strftime("%Y-%m-%d %H:%M:%S")
    elif isinstance(obj, decimal.Decimal):
        return float(obj)

import json
from sqlalchemy import text

# db is SessionLocal() object 

app_sql = 'SELECT * FROM app_info ORDER BY app_id LIMIT :page,:page_size'

# The next two are the parameters passed in
page = 1
page_size = 10

# execute sql and return a <class 'sqlalchemy.engine.result.ResultProxy'> object
app_list = db.execute(text(app_sql), {'page': page, 'page_size': page_size})

# serialize
res = json.loads(json.dumps([dict(r) for r in app_list], default=alchemy_encoder))

如果不行，请忽略我的回答。我在这里提到它

https://codeandlife.com/2014/12/07/sqlalchemy-results-to-json-the-easy-way/

step1:
class CNAME:
   ...
   def as_dict(self):
       return {item.name: getattr(self, item.name) for item in self.__table__.columns}

step2:
list = []
for data in session.query(CNAME).all():
    list.append(data.as_dict())

step3:
return jsonify(list)

Python 3.7+和Flask 1.1+可以使用内置的数据类包

from dataclasses import dataclass
from datetime import datetime
from flask import Flask, jsonify
from flask_sqlalchemy import SQLAlchemy


app = Flask(__name__)
db = SQLAlchemy(app)


@dataclass
class User(db.Model):
  id: int
  email: str

  id = db.Column(db.Integer, primary_key=True, auto_increment=True)
  email = db.Column(db.String(200), unique=True)


@app.route('/users/')
def users():
  users = User.query.all()
  return jsonify(users)  


if __name__ == "__main__":
  users = User(email="user1@gmail.com"), User(email="user2@gmail.com")
  db.create_all()
  db.session.add_all(users)
  db.session.commit()
  app.run()

/users/路由现在将返回一个用户列表。

[
  {"email": "user1@gmail.com", "id": 1},
  {"email": "user2@gmail.com", "id": 2}
]

自动序列化相关模型

@dataclass
class Account(db.Model):
  id: int
  users: User

  id = db.Column(db.Integer)
  users = db.relationship(User)  # User model would need a db.ForeignKey field

jsonify(account)的响应是这样的。

{  
   "id":1,
   "users":[  
      {  
         "email":"user1@gmail.com",
         "id":1
      },
      {  
         "email":"user2@gmail.com",
         "id":2
      }
   ]
}

覆盖默认的JSON编码器

from flask.json import JSONEncoder


class CustomJSONEncoder(JSONEncoder):
  "Add support for serializing timedeltas"

  def default(o):
    if type(o) == datetime.timedelta:
      return str(o)
    if type(o) == datetime.datetime:
      return o.isoformat()
    return super().default(o)

app.json_encoder = CustomJSONEncoder      

你可以像这样将RowProxy转换为dict:

 d = dict(row.items())

然后将其序列化为JSON(必须为datetime值等指定编码器) 如果您只想要一条记录(而不是相关记录的完整层次结构)，这并不难。

json.dumps([(dict(row.items())) for row in rs])

你可以把你的对象输出为一个字典:

class User:
   def as_dict(self):
       return {c.name: getattr(self, c.name) for c in self.__table__.columns}

然后使用User.as_dict()序列化对象。

如将sqlalchemy行对象转换为python dict中所述