仅在希望为发布版本删除检查的情况下使用断言。请记住，如果不在调试模式下编译，断言将不会触发。

对于检查为空的示例，如果这是在仅限内部的API中，我可能会使用断言。如果它在一个公共API中，我肯定会使用显式检查和抛出。

您应该使用Debug。断言来测试程序中的逻辑错误。编译器只能通知您语法错误。因此，您肯定应该使用Assert语句来测试逻辑错误。比如测试一个销售汽车的项目，只有蓝色的宝马可以得到15%的折扣。编译器不能告诉你你的程序在执行这个操作时逻辑上是否正确，但是assert语句可以。

断言用于捕获程序员(您的)错误，而不是用户错误。只有在用户不可能触发断言时才应该使用它们。例如，如果你正在编写一个API，在API用户调用的任何方法中，都不应该使用断言来检查参数是否为空。但是它可以在一个私有方法中使用，而不是作为API的一部分公开，以断言您的代码永远不会在不应该传递null参数时传递null参数。

当我不确定时，我通常更喜欢异常而不是断言。

摘自《实用程序员:从熟练工到高手》

Leave Assertions Turned On There is a common misunderstanding about assertions, promulgated by the people who write compilers and language environments. It goes something like this: Assertions add some overhead to code. Because they check for things that should never happen, they'll get triggered only by a bug in the code. Once the code has been tested and shipped, they are no longer needed, and should be turned off to make the code run faster. Assertions are a debugging facility. There are two patently wrong assumptions here. First, they assume that testing finds all the bugs. In reality, for any complex program you are unlikely to test even a miniscule percentage of the permutations your code will be put through (see Ruthless Testing). Second, the optimists are forgetting that your program runs in a dangerous world. During testing, rats probably won't gnaw through a communications cable, someone playing a game won't exhaust memory, and log files won't fill the hard drive. These things might happen when your program runs in a production environment. Your first line of defense is checking for any possible error, and your second is using assertions to try to detect those you've missed. Turning off assertions when you deliver a program to production is like crossing a high wire without a net because you once made it across in practice. There's dramatic value, but it's hard to get life insurance. Even if you do have performance issues, turn off only those assertions that really hit you.

摘自Code Complete (Wikipedia):

8 Defensive Programming 8.2 Assertions An assertion is code that’s used during development—usually a routine or macro—that allows a program to check itself as it runs. When an assertion is true, that means everything is operating as expected. When it’s false, that means it has detected an unexpected error in the code. For example, if the system assumes that a customer-information file will never have more than 50,000 records, the program might contain an assertion that the number of records is lessthan or equal to 50,000. As long as the number of records is less than or equal to 50,000, the assertion will be silent. If it encounters more than 50,000 records, however, it will loudly “assert” that there is an error in the program. Assertions are especially useful in large, complicated programs and in high reliability programs. They enable programmers to more quickly flush out mismatched interface assumptions, errors that creep in when code is modified, and so on. An assertion usually takes two arguments: a boolean expression that describes the assumption that’s supposed to be true and a message to display if it isn’t. (…) Normally, you don’t want users to see assertion messages in production code; assertions are primarily for use during development and maintenance. Assertions are normally compiled into the code at development time and compiled out of the code for production. During development, assertions flush out contradictory assumptions, unexpected conditions, bad values passed to routines, and so on. During production, they are compiled out of the code so that the assertions don’t degrade system performance.

如果您希望在生产代码中使用断言(即发布构建)，您可以使用Trace。Assert而不是Debug.Assert。

这当然会增加生产可执行文件的开销。

此外，如果您的应用程序在用户界面模式下运行，则默认情况下将显示断言对话框，这可能会让您的用户感到不安。

您可以通过删除DefaultTraceListener来覆盖这种行为:查看Trace的文档。MSDN中的侦听器。

总之,

使用调试。自由断言，以帮助在调试版本中捕获错误。 如果你使用Trace。在用户界面模式下断言，您可能希望删除DefaultTraceListener以避免让用户感到不安。 如果你测试的条件是你的应用程序无法处理的，你可能最好抛出一个异常，以确保执行不会继续。请注意，用户可以选择忽略断言。