子类UILabel。(File-New-File- CocoaTouchClass-make UILabel的子类)。

//  sampleLabel.swift

import UIKit

class sampleLabel: UILabel {

 let topInset = CGFloat(5.0), bottomInset = CGFloat(5.0), leftInset = CGFloat(8.0), rightInset = CGFloat(8.0)

 override func drawTextInRect(rect: CGRect) {

  let insets: UIEdgeInsets = UIEdgeInsets(top: topInset, left: leftInset, bottom: bottomInset, right: rightInset)
  super.drawTextInRect(UIEdgeInsetsInsetRect(rect, insets))

 }
 override func intrinsicContentSize() -> CGSize {
  var intrinsicSuperViewContentSize = super.intrinsicContentSize()
  intrinsicSuperViewContentSize.height += topInset + bottomInset
  intrinsicSuperViewContentSize.width += leftInset + rightInset
  return intrinsicSuperViewContentSize
 }
}

ViewController:

override func viewDidLoad() {
  super.viewDidLoad()

  let labelName = sampleLabel(frame: CGRectMake(0, 100, 300, 25))
  labelName.text = "Sample Label"
  labelName.backgroundColor =  UIColor.grayColor()

  labelName.textColor = UIColor.redColor()
  labelName.shadowColor = UIColor.blackColor()
  labelName.font = UIFont(name: "HelveticaNeue", size: CGFloat(22))
  self.view.addSubview(labelName)
 }

或者将Storyboard上的自定义UILabel类关联为Label的类。

斯威夫特4

易于使用的解决方案，可用于项目中的所有UILabel子。

例子:

let label = UILabel()
    label.<Do something>
    label.padding = UIEdgeInsets(top: 0, left: 16, bottom: 0, right: 0)

UILabel扩展

import UIKit

extension UILabel {
    private struct AssociatedKeys {
        static var padding = UIEdgeInsets()
    }

    public var padding: UIEdgeInsets? {
        get {
            return objc_getAssociatedObject(self, &AssociatedKeys.padding) as? UIEdgeInsets
        }
        set {
            if let newValue = newValue {
                objc_setAssociatedObject(self, &AssociatedKeys.padding, newValue as UIEdgeInsets?, objc_AssociationPolicy.OBJC_ASSOCIATION_RETAIN_NONATOMIC)
            }
        }
    }

    override open func draw(_ rect: CGRect) {
        if let insets = padding {
            self.drawText(in: rect.inset(by: insets))
        } else {
            self.drawText(in: rect)
        }
    }

    override open var intrinsicContentSize: CGSize {
        guard let text = self.text else { return super.intrinsicContentSize }

        var contentSize = super.intrinsicContentSize
        var textWidth: CGFloat = frame.size.width
        var insetsHeight: CGFloat = 0.0
        var insetsWidth: CGFloat = 0.0

        if let insets = padding {
            insetsWidth += insets.left + insets.right
            insetsHeight += insets.top + insets.bottom
            textWidth -= insetsWidth
        }

        let newSize = text.boundingRect(with: CGSize(width: textWidth, height: CGFloat.greatestFiniteMagnitude),
                                        options: NSStringDrawingOptions.usesLineFragmentOrigin,
                                        attributes: [NSAttributedString.Key.font: self.font], context: nil)

        contentSize.height = ceil(newSize.size.height) + insetsHeight
        contentSize.width = ceil(newSize.size.width) + insetsWidth

        return contentSize
    }
}

Swift 3、iOS10解决方案:

open class UIInsetLabel: UILabel {

    open var insets : UIEdgeInsets = UIEdgeInsets() {
        didSet {
            super.invalidateIntrinsicContentSize()
        }
    }

    open override var intrinsicContentSize: CGSize {
        var size = super.intrinsicContentSize
        size.width += insets.left + insets.right
        size.height += insets.top + insets.bottom
        return size
    }

    override open func drawText(in rect: CGRect) {
        return super.drawText(in: UIEdgeInsetsInsetRect(rect, insets))
    }
}

斯威夫特5

在layoutSubviews()方法上，更改UILabel的插入，如下所示。

  override func layoutSubviews() {
    super.layoutSubviews()

    label.frame = label.frame.inset(by: UIEdgeInsets(top: 5, left: 10, bottom: 5, right: 10))
  }

简单填充(Swift 3.0, Alvin George回答):

  class NewLabel: UILabel {

        override func textRect(forBounds bounds: CGRect, limitedToNumberOfLines numberOfLines: Int) -> CGRect {
                return self.bounds.insetBy(dx: CGFloat(15.0), dy: CGFloat(15.0))
        }

        override func draw(_ rect: CGRect) {
                super.drawText(in: self.bounds.insetBy(dx: CGFloat(5.0), dy: CGFloat(5.0)))
        }

  }

斯威夫特3

import UIKit

class PaddingLabel: UILabel {

   @IBInspectable var topInset: CGFloat = 5.0
   @IBInspectable var bottomInset: CGFloat = 5.0
   @IBInspectable var leftInset: CGFloat = 5.0
   @IBInspectable var rightInset: CGFloat = 5.0

   override func drawText(in rect: CGRect) {
      let insets = UIEdgeInsets(top: topInset, left: leftInset, bottom: bottomInset, right: rightInset)
      super.drawText(in: UIEdgeInsetsInsetRect(rect, insets))
   }

   override var intrinsicContentSize: CGSize {
      get {
         var contentSize = super.intrinsicContentSize
         contentSize.height += topInset + bottomInset
         contentSize.width += leftInset + rightInset
         return contentSize
      }
   }
}