Julen的解决方案有点难以阅读，这里有更清晰和准确的反应代码，供那些根据标题而不是问题的微小细节绊倒他的人使用。

Tl;dr版本:当你要更新到观察者发送调用一个调度方法，反过来实际上会通知观察者(或执行ajax等)

使用示例组件jsfiddle完成jsfiddle

var InputField = React.createClass({

    getDefaultProps: function () {
        return {
            initialValue: '',
            onChange: null
        };
    },

    getInitialState: function () {
        return {
            value: this.props.initialValue
        };
    },

    render: function () {
        var state = this.state;
        return (
            <input type="text"
                   value={state.value}
                   onChange={this.onVolatileChange} />
        );
    },

    onVolatileChange: function (event) {
        this.setState({ 
            value: event.target.value 
        });

        this.scheduleChange();
    },

    scheduleChange: _.debounce(function () {
        this.onChange();
    }, 250),

    onChange: function () {
        var props = this.props;
        if (props.onChange != null) {
            props.onChange.call(this, this.state.value)
        }
    },

});

不受控制的组件

你可以使用event.persist()方法。

下面是一个使用下划线_.debounce()的例子:

var SearchBox = React.createClass({

  componentWillMount: function () {
     this.delayedCallback = _.debounce(function (event) {
       // `event.target` is accessible now
     }, 1000);
  },

  onChange: function (event) {
    event.persist();
    this.delayedCallback(event);
  },

  render: function () {
    return (
      <input type="search" onChange={this.onChange} />
    );
  }

});

编辑:请看这个JSFiddle

控制组件

更新:上面的例子显示了一个不受控制的组件。我一直在使用受控元素，这里是上面的另一个例子，但没有使用event.persist()“欺骗”。

JSFiddle也是可用的。不带下划线的示例

var SearchBox = React.createClass({
    getInitialState: function () {
        return {
            query: this.props.query
        };
    },

    componentWillMount: function () {
       this.handleSearchDebounced = _.debounce(function () {
           this.props.handleSearch.apply(this, [this.state.query]);
       }, 500);
    },

    onChange: function (event) {
      this.setState({query: event.target.value});
      this.handleSearchDebounced();
    },

    render: function () {
      return (
        <input type="search"
               value={this.state.query}
               onChange={this.onChange} />
      );
    }
});


var Search = React.createClass({
    getInitialState: function () {
        return {
            result: this.props.query
        };
    },

    handleSearch: function (query) {
        this.setState({result: query});
    },

    render: function () {
      return (
        <div id="search">
          <SearchBox query={this.state.result}
                     handleSearch={this.handleSearch} />
          <p>You searched for: <strong>{this.state.result}</strong></p>
        </div>
      );
    }
});

React.render(<Search query="Initial query" />, document.body);

编辑:更新示例和JSFiddles到React 0.12

编辑:更新的例子，以解决Sebastien Lorber提出的问题

编辑:更新的jsfiddle不使用下划线和使用纯javascript debounce。

今天遇到了这个问题。使用setTimeout和clearTimeout解决。

我将给出一个你可以适应的例子:

import React, { Component } from 'react'

const DEBOUNCE_TIME = 500

class PlacesAutocomplete extends Component {
  debounceTimer = null;

  onChangeHandler = (event) => {
    // Clear the last registered timer for the function
    clearTimeout(this.debounceTimer);

    // Set a new timer
    this.debounceTimer = setTimeout(
      // Bind the callback function to pass the current input value as arg
      this.getSuggestions.bind(null, event.target.value), 
      DEBOUNCE_TIME
    )
  }

  // The function that is being debounced
  getSuggestions = (searchTerm) => {
    console.log(searchTerm)
  }

  render() {
    return (
      <input type="text" onChange={this.onChangeHandler} />
    )
  }
}

export default PlacesAutocomplete

你也可以在它自己的函数组件中重构它:

import React from 'react'

function DebouncedInput({ debounceTime, callback}) {
  let debounceTimer = null
  return (
    <input type="text" onChange={(event) => {
      clearTimeout(debounceTimer);

      debounceTimer = setTimeout(
        callback.bind(null, event.target.value), 
        debounceTime
      )
    }} />
  )
}

export default DebouncedInput

像这样使用它:

import React, { Component } from 'react'
import DebouncedInput from '../DebouncedInput';

class PlacesAutocomplete extends Component {
  debounceTimer = null;

  getSuggestions = (searchTerm) => {
    console.log(searchTerm)
  }

  render() {
    return (
      <DebouncedInput debounceTime={500} callback={this.getSuggestions} />
    )
  }
}

export default PlacesAutocomplete

如果你不喜欢添加lodash或任何其他包:

import React, { useState, useRef } from "react";

function DebouncedInput() {
  const [isRefetching, setIsRefetching] = useState(false);
  const [searchTerm, setSearchTerm] = useState("");
  const previousSearchTermRef = useRef("");

  function setDebouncedSearchTerm(value) {
    setIsRefetching(true);
    setSearchTerm(value);
    previousSearchTermRef.current = value;
    setTimeout(async () => {
      if (previousSearchTermRef.current === value) {
        try {
          // await refetch();
        } finally {
          setIsRefetching(false);
        }
      }
    }, 500);
  }

  return (
    <input
      value={searchTerm}
      onChange={(event) => setDebouncedSearchTerm(event.target.value)}
    />
  );
}

如果你正在使用redux，你可以通过中间件以一种非常优雅的方式做到这一点。你可以这样定义Debounce中间件:

var timeout;
export default store => next => action => {
  const { meta = {} } = action;
  if(meta.debounce){
    clearTimeout(timeout);
    timeout = setTimeout(() => {
      next(action)
    }, meta.debounce)
  }else{
    next(action)
  }
}

然后你可以添加debounging到动作创建者，比如:

export default debouncedAction = (payload) => ({
  type : 'DEBOUNCED_ACTION',
  payload : payload,
  meta : {debounce : 300}
}

实际上已经有中间件你可以脱离npm来为你做这件事。

class UserListComponent extends Component {
    constructor(props) {
        super(props);
        this.searchHandler = this.keyUpHandler.bind(this);
        this.getData = this.getData.bind(this);
        this.magicSearch = this.magicSearch.bind(this,500);
    }
    getData = (event) => {
        console.log(event.target.value);
    }
    magicSearch = function (fn, d) {
        let timer;
        return function () {
            let context = this;
            clearTimeout(timer);
            timer = setTimeout(() => {
                fn.apply(context, arguments)
            }, d);
        }
    }
    keyUpHandler = this.magicSearch(this.getData, 500);
    render() {
        return (
             <input type="text" placeholder="Search" onKeyUp={this.searchHandler} />
        )
    }
}