好的，根据你说的，我用这个：

var DecimalSeparator = Number("1.2").toLocaleString().substr(1,1);

var AmountWithCommas = Amount.toLocaleString();
var arParts = String(AmountWithCommas).split(DecimalSeparator);
var intPart = arParts[0];
var decPart = (arParts.length > 1 ? arParts[1] : '');
decPart = (decPart + '00').substr(0,2);

return '£ ' + intPart + DecimalSeparator + decPart;

我对改进建议持开放态度（我不希望仅仅为了做到这一点而加入YUI：-）

我已经知道我应该检测“.”而不是仅仅将其用作小数分隔符。。。

我主要基于VisionN的回答：

function format (val) {
  val = (+val).toLocaleString();
  val = (+val).toFixed(2);
  val += "";
  return val.replace(/(\d)(?=(\d{3})+(?:\.\d+)?$)/g, "$1" + format.thousands);
}

(function (isUS) {
  format.decimal =   isUS ? "." : ",";
  format.thousands = isUS ? "," : ".";
}(("" + (+(0.00).toLocaleString()).toFixed(2)).indexOf(".") > 0));

我用输入进行了测试：

[   ""
  , "1"
  , "12"
  , "123"
  , "1234"
  , "12345"
  , "123456"
  , "1234567"
  , "12345678"
  , "123456789"
  , "1234567890"
  , ".12"
  , "1.12"
  , "12.12"
  , "123.12"
  , "1234.12"
  , "12345.12"
  , "123456.12"
  , "1234567.12"
  , "12345678.12"
  , "123456789.12"
  , "1234567890.12"
  , "1234567890.123"
  , "1234567890.125"
].forEach(function (item) {
  console.log(format(item));
});

得到了这些结果：

0.00
1.00
12.00
123.00
1,234.00
12,345.00
123,456.00
1,234,567.00
12,345,678.00
123,456,789.00
1,234,567,890.00
0.12
1.12
12.12
123.12
1,234.12
12,345.12
123,456.12
1,234,567.12
12,345,678.12
123,456,789.12
1,234,567,890.12
1,234,567,890.12
1,234,567,890.13

只是为了好玩。

一个简单的选项，通过先反转字符串和基本正则表达式来正确放置逗号。

String.prototype.reverse = function() {
    return this.split('').reverse().join('');
};

Number.prototype.toCurrency = function( round_decimal /*boolean*/ ) {       
     // format decimal or round to nearest integer
     var n = this.toFixed( round_decimal ? 0 : 2 );

     // convert to a string, add commas every 3 digits from left to right 
     // by reversing string
     return (n + '').reverse().replace( /(\d{3})(?=\d)/g, '$1,' ).reverse();
};

String.prototype.toPrice = function () {
    var v;
    if (/^\d+(,\d+)$/.test(this))
        v = this.replace(/,/, '.');
    else if (/^\d+((,\d{3})*(\.\d+)?)?$/.test(this))
        v = this.replace(/,/g, "");
    else if (/^\d+((.\d{3})*(,\d+)?)?$/.test(this))
        v = this.replace(/\./g, "").replace(/,/, ".");
    var x = parseFloat(v).toFixed(2).toString().split("."),
    x1 = x[0],
    x2 = ((x.length == 2) ? "." + x[1] : ".00"),
    exp = /^([0-9]+)(\d{3})/;
    while (exp.test(x1))
        x1 = x1.replace(exp, "$1" + "," + "$2");
    return x1 + x2;
}

alert("123123".toPrice()); //123,123.00
alert("123123,316".toPrice()); //123,123.32
alert("12,312,313.33213".toPrice()); //12,312,313.33
alert("123.312.321,32132".toPrice()); //123,312,321.32

YUI代码库使用以下格式：

format: function(nData, oConfig) {
    oConfig = oConfig || {};

    if(!YAHOO.lang.isNumber(nData)) {
        nData *= 1;
    }

    if(YAHOO.lang.isNumber(nData)) {
        var sOutput = nData + "";
        var sDecimalSeparator = (oConfig.decimalSeparator) ? oConfig.decimalSeparator : ".";
        var nDotIndex;

        // Manage decimals
        if(YAHOO.lang.isNumber(oConfig.decimalPlaces)) {
            // Round to the correct decimal place
            var nDecimalPlaces = oConfig.decimalPlaces;
            var nDecimal = Math.pow(10, nDecimalPlaces);
            sOutput = Math.round(nData*nDecimal)/nDecimal + "";
            nDotIndex = sOutput.lastIndexOf(".");

            if(nDecimalPlaces > 0) {
                // Add the decimal separator
                if(nDotIndex < 0) {
                    sOutput += sDecimalSeparator;
                    nDotIndex = sOutput.length-1;
                }
                // Replace the "."
                else if(sDecimalSeparator !== "."){
                    sOutput = sOutput.replace(".",sDecimalSeparator);
                }
                // Add missing zeros
                while((sOutput.length - 1 - nDotIndex) < nDecimalPlaces) {
                    sOutput += "0";
                }
            }
        }

        // Add the thousands separator
        if(oConfig.thousandsSeparator) {
            var sThousandsSeparator = oConfig.thousandsSeparator;
            nDotIndex = sOutput.lastIndexOf(sDecimalSeparator);
            nDotIndex = (nDotIndex > -1) ? nDotIndex : sOutput.length;
            var sNewOutput = sOutput.substring(nDotIndex);
            var nCount = -1;
            for (var i=nDotIndex; i>0; i--) {
                nCount++;
                if ((nCount%3 === 0) && (i !== nDotIndex)) {
                    sNewOutput = sThousandsSeparator + sNewOutput;
                }
                sNewOutput = sOutput.charAt(i-1) + sNewOutput;
            }
            sOutput = sNewOutput;
        }

        // Prepend prefix
        sOutput = (oConfig.prefix) ? oConfig.prefix + sOutput : sOutput;

        // Append suffix
        sOutput = (oConfig.suffix) ? sOutput + oConfig.suffix : sOutput;

        return sOutput;
    }
    // Still not a number. Just return it unaltered
    else {
        return nData;
    }
}

它需要编辑，因为YUI库是可配置的，比如用“.”替换oConfig.decimalSeparator。

JavaScript中没有“formatNumber”的等价物。你可以自己写，也可以找一个已经这样做的库。