这里有一个普通JavaScript的简单格式化程序：

function numberFormatter (num) {
    console.log(num)
    var wholeAndDecimal = String(num.toFixed(2)).split(".");
    console.log(wholeAndDecimal)
    var reversedWholeNumber = Array.from(wholeAndDecimal[0]).reverse();
    var formattedOutput = [];

    reversedWholeNumber.forEach( (digit, index) => {
        formattedOutput.push(digit);
        if ((index + 1) % 3 === 0 && index < reversedWholeNumber.length - 1) {
            formattedOutput.push(",");
        }
    })

    formattedOutput = formattedOutput.reverse().join('') + "." + wholeAndDecimal[1];

    return formattedOutput;
}

一种仅满足原始要求的极简方法：

function formatMoney(n) {
    return "$ " + (Math.round(n * 100) / 100).toLocaleString();
}

@丹尼尔·马格廖拉：你说得对。以上是一个仓促而不完整的实施。以下是正确的实施方式：

function formatMoney(n) {
    return "$ " + n.toLocaleString().split(".")[0] + "."
        + n.toFixed(2).split(".")[1];
}

乔纳森·M的代码对我来说太复杂了，所以我重写了它，在Firefox v30上获得了30%的速度提升，在Chrome v35上获得了60%的速度提升(http://jsperf.com/number-formating2):

Number.prototype.formatNumber = function(decPlaces, thouSeparator, decSeparator) {
    decPlaces = isNaN(decPlaces = Math.abs(decPlaces)) ? 2 : decPlaces;
    decSeparator = decSeparator == undefined ? "." : decSeparator;
    thouSeparator = thouSeparator == undefined ? "," : thouSeparator;

    var n = this.toFixed(decPlaces);
    if (decPlaces) {
        var i = n.substr(0, n.length - (decPlaces + 1));
        var j = decSeparator + n.substr(-decPlaces);
    } else {
        i = n;
        j = '';
    }

    function reverse(str) {
        var sr = '';
        for (var l = str.length - 1; l >= 0; l--) {
            sr += str.charAt(l);
        }
        return sr;
    }

    if (parseInt(i)) {
        i = reverse(reverse(i).replace(/(\d{3})(?=\d)/g, "$1" + thouSeparator));
    }
    return i + j;
};

用法：

var sum = 123456789.5698;
var formatted = '$' + sum.formatNumber(2, ',', '.'); // "$123,456,789.57"

Patrick Desjardins（前Daok）的例子对我很有用。如果有人感兴趣，我将其移植到CoffeeScript。

Number.prototype.toMoney = (decimals = 2, decimal_separator = ".", thousands_separator = ",") ->
    n = this
    c = if isNaN(decimals) then 2 else Math.abs decimals
    sign = if n < 0 then "-" else ""
    i = parseInt(n = Math.abs(n).toFixed(c)) + ''
    j = if (j = i.length) > 3 then j % 3 else 0
    x = if j then i.substr(0, j) + thousands_separator else ''
    y = i.substr(j).replace(/(\d{3})(?=\d)/g, "$1" + thousands_separator)
    z = if c then decimal_separator + Math.abs(n - i).toFixed(c).slice(2) else ''
    sign + x + y + z

JavaScript中有一个内置函数toFixed：

var num = new Number(349);
document.write("$" + num.toFixed(2));

一个简单的选项，通过先反转字符串和基本正则表达式来正确放置逗号。

String.prototype.reverse = function() {
    return this.split('').reverse().join('');
};

Number.prototype.toCurrency = function( round_decimal /*boolean*/ ) {       
     // format decimal or round to nearest integer
     var n = this.toFixed( round_decimal ? 0 : 2 );

     // convert to a string, add commas every 3 digits from left to right 
     // by reversing string
     return (n + '').reverse().replace( /(\d{3})(?=\d)/g, '$1,' ).reverse();
};