从Python 3.8开始，并引入赋值表达式(PEP 572)(:=运算符)，我们可以在一个列表理解式中应用替换:

# text = "The quick brown fox jumps over the lazy dog"
# replacements = [("brown", "red"), ("lazy", "quick")]
[text := text.replace(a, b) for a, b in replacements]
# text = 'The quick red fox jumps over the quick dog'

我的方法是首先将字符串标记化，然后决定每个标记是否包含它。

潜在地，如果我们可以假设一个hashmap/set的O(1)查找，可能会更好:

remove_words = {"we", "this"}
target_sent = "we should modify this string"
target_sent_words = target_sent.split()
filtered_sent = " ".join(list(filter(lambda word: word not in remove_words, target_sent_words)))

Filtered_sent现在是'应该修改字符串'

为什么没有这样的解决方案呢?

s = "The quick brown fox jumps over the lazy dog"
for r in (("brown", "red"), ("lazy", "quick")):
    s = s.replace(*r)

#output will be:  The quick red fox jumps over the quick dog

这是我对这个问题的解决办法。我把它用在聊天机器人上，一次替换不同的单词。

def mass_replace(text, dct):
    new_string = ""
    old_string = text
    while len(old_string) > 0:
        s = ""
        sk = ""
        for k in dct.keys():
            if old_string.startswith(k):
                s = dct[k]
                sk = k
        if s:
            new_string+=s
            old_string = old_string[len(sk):]
        else:
            new_string+=old_string[0]
            old_string = old_string[1:]
    return new_string

print mass_replace("The dog hunts the cat", {"dog":"cat", "cat":"dog"})

这就成了猫捉狗

这是我的0.02美元。它基于Andrew Clark的答案，只是更清楚一点，它还涵盖了当一个字符串被替换为另一个字符串的子字符串时的情况(更长的字符串胜出)

def multireplace(string, replacements):
    """
    Given a string and a replacement map, it returns the replaced string.

    :param str string: string to execute replacements on
    :param dict replacements: replacement dictionary {value to find: value to replace}
    :rtype: str

    """
    # Place longer ones first to keep shorter substrings from matching
    # where the longer ones should take place
    # For instance given the replacements {'ab': 'AB', 'abc': 'ABC'} against 
    # the string 'hey abc', it should produce 'hey ABC' and not 'hey ABc'
    substrs = sorted(replacements, key=len, reverse=True)

    # Create a big OR regex that matches any of the substrings to replace
    regexp = re.compile('|'.join(map(re.escape, substrs)))

    # For each match, look up the new string in the replacements
    return regexp.sub(lambda match: replacements[match.group(0)], string)

这就是这个要点，如果你有任何建议，请随意修改。

这里有一个使用reduce的第一个解决方案的变体，如果你喜欢功能性的。：）

repls = {'hello' : 'goodbye', 'world' : 'earth'}
s = 'hello, world'
reduce(lambda a, kv: a.replace(*kv), repls.iteritems(), s)

马蒂诺的版本更好:

repls = ('hello', 'goodbye'), ('world', 'earth')
s = 'hello, world'
reduce(lambda a, kv: a.replace(*kv), repls, s)