另一种可能是在依赖关系中混合发布和调试构建。例如，程序集A依赖于程序集B, A是在调试模式下构建的，而GAC中的B副本是在发布模式下构建的，反之亦然。

我在Visual Studio Pro 2008中看到了这一点，当时两个项目构建了具有相同名称的程序集，一个是类库SDF.dll，另一个是使用程序集名称sdf.exe引用程序库。 当我更改引用程序集的名称时，异常消失了

I got this error because I had a class in an assembly 'C' which was on version 4.5 of the framework, implementing an interface in assembly 'A' which was on version 4.5.1 of the framework and serving as the base class to assembly 'B' which was also on version 4.5.1 of the framework. The system threw the exception while trying to load assembly 'B'. Additionally, I had installed some nuget packages targeting .net 4.5.1 on all three assemblies. For some reason, even though the nuget references were not showing in assembly 'B', it was building successfully.

事实证明，真正的问题是程序集引用了包含接口的nuget包的不同版本，并且接口签名在不同版本之间发生了变化。

当我尝试在dot net 5中使用自定义的AssemblyLoadContext(没有AppDomain创建)和共享类型(你需要使用它来调用插件方法而没有反射)实现插件程序集加载时，我得到了这个问题。这篇文章对我没有任何帮助。以下是我解决这个问题的方法:

为了允许调试插件加载没有问题-设置项目输出路径到主机应用程序bin文件夹。您将调试插件项目构建后得到的相同程序集。这可能是临时更改(仅用于调试)。 要修复TypeLoadException异常，你需要将所有“契约程序集”引用的程序集加载为共享程序集(运行时程序集除外)。检查加载器上下文实现(在构造函数中加载sharedAssemblies):

    public class PluginAssemblyLoadContext : AssemblyLoadContext
    {
        private AssemblyDependencyResolver _resolver;
        
        private IDictionary<string, Assembly> _loadedAssemblies;
        
        private IDictionary<string, Assembly> _sharedAssemblies;

        private AssemblyLoadContext DefaultAlc;

        private string _path;

        public PluginAssemblyLoadContext(string path, bool isCollectible, params Type[] sharedTypes)
             : this(path, isCollectible, sharedTypes.Select(t => t.Assembly).ToArray())
        {
        }

        public PluginAssemblyLoadContext(string path, bool isCollectible, params Assembly[] sharedAssemblies)
             : base(isCollectible: isCollectible)
        {

            _path = path;

            DefaultAlc = GetLoadContext(Assembly.GetExecutingAssembly()) ?? Default;

            var fileInfo = new FileInfo(_path);
            if (fileInfo.Exists)
            {
                _resolver = new AssemblyDependencyResolver(_path);

                _sharedAssemblies = new Dictionary<string, Assembly>(StringComparer.OrdinalIgnoreCase);
                foreach (var a in sharedAssemblies.Distinct())
                {
                    LoadReferencedAssemblies(a);
                }

                _loadedAssemblies = new Dictionary<string, Assembly>();

                var assembly = LoadFromAssemblyPath(fileInfo.FullName);

                _loadedAssemblies.Add(fileInfo.FullName, assembly);
            }
            else
            {
                throw new FileNotFoundException($"File does not exist: {_path}");
            }
        }

        public bool LoadReferencedAssemblies(Assembly assembly)
        {
            if (assembly == null)
            {
                throw new ArgumentNullException(nameof(assembly));
            }
            if (string.IsNullOrEmpty(assembly.Location))
            {
                throw new NotSupportedException($"Assembly location is empty string or null: {assembly.FullName}");
            }
            var alc = GetLoadContext(assembly);
            if (alc == this)
            {
                throw new InvalidOperationException($"Circular assembly loader dependency detected");
            }
            if (!_sharedAssemblies.ContainsKey(assembly.Location))
            {
                _sharedAssemblies.Add(assembly.Location, assembly);

                foreach (var an in assembly.GetReferencedAssemblies())
                {
                    var ra = alc.LoadFromAssemblyName(an);
                    LoadReferencedAssemblies(ra);
                }
                return true;
            }
            else
            {
                return false;
            }
        }

        public IEnumerable<Type> GetCommandTypes<T>()
        {
            var cmdType = typeof(T);
            return _loadedAssemblies.Values.SelectMany(a => a.GetTypes()).Where(t => cmdType.IsAssignableFrom(t));
        }

        public IEnumerable<T> CreateCommands<T>(Assembly assembly)
        {
            foreach (var cmdType in GetCommandTypes<T>())
            {
                yield return (T)Activator.CreateInstance(cmdType);
            }
        }

        protected override Assembly Load(AssemblyName assemblyName)
        {
            var path = _resolver.ResolveAssemblyToPath(assemblyName);
            if (path != null)
            {
                if (_sharedAssemblies.ContainsKey(path))
                {
                    return _sharedAssemblies[path];
                }
                if (_loadedAssemblies.ContainsKey(path))
                {
                    return _loadedAssemblies[path];
                }
                return LoadFromAssemblyPath(path);
            }     
            return DefaultAlc.LoadFromAssemblyName(assemblyName);
        }
    }

用法:

var loader = new PluginAssemblyLoadContext(fullPath, false, typeof(IPluginCommand));
loader.CreateCommands<IPluginCommand>()...

当我的集成测试项目试图加载一个不包含接口依赖项解析的DLL时，我遇到了这个错误:

集成测试项目(参考主项目，但不是 StructureMap) 主要项目(引用StructureMap项目-使用 类构造函数中的接口) StructureMap项目(IoC - For().Use();)

这将导致抛出错误，因为它无法找到具体的实现。我在测试配置中排除了DLL，错误消失了

如果使用assembly . loadfrom (String)加载程序集，并且正在引用已经使用assembly . load (Byte[])加载的程序集，也可能导致此错误。

例如，你嵌入了主应用程序的引用程序集作为资源，但你的应用程序从特定的文件夹加载插件。

你应该使用Load而不是LoadFrom。下面的代码将完成这项工作:

private static Assembly LoadAssemblyFromFile( String filePath )
{
    using( Stream stream = File.OpenRead( filePath ) )
    {
        if( !ReferenceEquals( stream, null ) )
        {
            Byte[] assemblyData = new Byte[stream.Length];
            stream.Read( assemblyData, 0, assemblyData.Length );
            return Assembly.Load( assemblyData );
        }
    }
    return null;
}