两全其美:

using System.Runtime.InteropServices;

    [DllImport("winmm.dll", EntryPoint = "timeBeginPeriod", SetLastError = true)]
    private static extern uint TimeBeginPeriod(uint uMilliseconds);

    [DllImport("winmm.dll", EntryPoint = "timeEndPeriod", SetLastError = true)]
    private static extern uint TimeEndPeriod(uint uMilliseconds);
    /**
     * Extremely accurate sleep is needed here to maintain performance so system resolution time is increased
     */
    private void accurateSleep(int milliseconds)
    {
        //Increase timer resolution from 20 miliseconds to 1 milisecond
        TimeBeginPeriod(1);
        Stopwatch stopwatch = new Stopwatch();//Makes use of QueryPerformanceCounter WIN32 API
        stopwatch.Start();

        while (stopwatch.ElapsedMilliseconds < milliseconds)
        {
            //So we don't burn cpu cycles
            if ((milliseconds - stopwatch.ElapsedMilliseconds) > 20)
            {
                Thread.Sleep(5);
            }
            else
            {
                Thread.Sleep(1);
            }
        }

        stopwatch.Stop();
        //Set it back to normal.
        TimeEndPeriod(1);
    }

可读性:

using System.Threading;
Thread.Sleep(TimeSpan.FromMilliseconds(50));

既然现在你有了async/await特性，那么最好的睡眠50ms的方法就是使用Task。延迟:

async void foo()
{
    // something
    await Task.Delay(50);
}

或者如果你的目标是。net 4(使用VS2010的Async CTP 3或Microsoft.Bcl.Async)，你必须使用:

async void foo()
{
    // something
    await TaskEx.Delay(50);
}

这样你就不会阻塞UI线程。

在Windows中无法指定确切的睡眠时间。你需要一个实时的操作系统。最好的方法是指定一个最小睡眠时间。然后由调度器在此之后唤醒线程。永远不要在GUI线程上调用. sleep()。

两全其美:

using System.Runtime.InteropServices;

    [DllImport("winmm.dll", EntryPoint = "timeBeginPeriod", SetLastError = true)]
    private static extern uint TimeBeginPeriod(uint uMilliseconds);

    [DllImport("winmm.dll", EntryPoint = "timeEndPeriod", SetLastError = true)]
    private static extern uint TimeEndPeriod(uint uMilliseconds);
    /**
     * Extremely accurate sleep is needed here to maintain performance so system resolution time is increased
     */
    private void accurateSleep(int milliseconds)
    {
        //Increase timer resolution from 20 miliseconds to 1 milisecond
        TimeBeginPeriod(1);
        Stopwatch stopwatch = new Stopwatch();//Makes use of QueryPerformanceCounter WIN32 API
        stopwatch.Start();

        while (stopwatch.ElapsedMilliseconds < milliseconds)
        {
            //So we don't burn cpu cycles
            if ((milliseconds - stopwatch.ElapsedMilliseconds) > 20)
            {
                Thread.Sleep(5);
            }
            else
            {
                Thread.Sleep(1);
            }
        }

        stopwatch.Stop();
        //Set it back to normal.
        TimeEndPeriod(1);
    }

System.Threading.Thread.Sleep(50);

记住，在主GUI线程中这样做会阻碍GUI的更新(它会感觉“迟缓”)。

只要把;使它也适用于VB.net。