如果你想要一个支持泛型基类型和接口的扩展方法，我扩展了sduplooy的答案:

    public static bool InheritsFrom(this Type t1, Type t2)
    {
        if (null == t1 || null == t2)
            return false;

        if (null != t1.BaseType &&
            t1.BaseType.IsGenericType &&
            t1.BaseType.GetGenericTypeDefinition() == t2)
        {
            return true;
        }

        if (InheritsFrom(t1.BaseType, t2))
            return true;

        return
            (t2.IsAssignableFrom(t1) && t1 != t2)
            ||
            t1.GetInterfaces().Any(x =>
              x.IsGenericType &&
              x.GetGenericTypeDefinition() == t2);
    }

通过使用tck的答案，也可以用以下LINQ查询完成:

bool isBar = foo.GetType().GetInterfaces().Any(x =>
  x.IsGenericType &&
  x.GetGenericTypeDefinition() == typeof(IBar<>));

试试下面的扩展。

public static bool Implements(this Type @this, Type @interface)
{
    if (@this == null || @interface == null) return false;
    return @interface.GenericTypeArguments.Length>0
        ? @interface.IsAssignableFrom(@this)
        : @this.GetInterfaces().Any(c => c.Name == @interface.Name);
}

为了测试它。创建

public interface IFoo { }
public interface IFoo<T> : IFoo { }
public interface IFoo<T, M> : IFoo<T> { }
public class Foo : IFoo { }
public class Foo<T> : IFoo { }
public class Foo<T, M> : IFoo<T> { }
public class FooInt : IFoo<int> { }
public class FooStringInt : IFoo<string, int> { }
public class Foo2 : Foo { }

以及测试方法

public void Test()
{
    Console.WriteLine(typeof(Foo).Implements(typeof(IFoo)));
    Console.WriteLine(typeof(FooInt).Implements(typeof(IFoo)));
    Console.WriteLine(typeof(FooInt).Implements(typeof(IFoo<>)));
    Console.WriteLine(typeof(FooInt).Implements(typeof(IFoo<int>)));
    Console.WriteLine(typeof(FooInt).Implements(typeof(IFoo<string>)));
    Console.WriteLine(typeof(FooInt).Implements(typeof(IFoo<,>)));
    Console.WriteLine(typeof(FooStringInt).Implements(typeof(IFoo<,>)));
    Console.WriteLine(typeof(FooStringInt).Implements(typeof(IFoo<string,int>)));
    Console.WriteLine(typeof(Foo<int,string>).Implements(typeof(IFoo<string>)));
 }

为了完全解决类型系统，我认为你需要处理递归，例如，IList<T>: ICollection<T>: IEnumerable<T>，否则你不会知道IList<int>最终实现了IEnumerable<>。

    /// <summary>Determines whether a type, like IList&lt;int&gt;, implements an open generic interface, like
    /// IEnumerable&lt;&gt;. Note that this only checks against *interfaces*.</summary>
    /// <param name="candidateType">The type to check.</param>
    /// <param name="openGenericInterfaceType">The open generic type which it may impelement</param>
    /// <returns>Whether the candidate type implements the open interface.</returns>
    public static bool ImplementsOpenGenericInterface(this Type candidateType, Type openGenericInterfaceType)
    {
        Contract.Requires(candidateType != null);
        Contract.Requires(openGenericInterfaceType != null);

        return
            candidateType.Equals(openGenericInterfaceType) ||
            (candidateType.IsGenericType && candidateType.GetGenericTypeDefinition().Equals(openGenericInterfaceType)) ||
            candidateType.GetInterfaces().Any(i => i.IsGenericType && i.ImplementsOpenGenericInterface(openGenericInterfaceType));

    }

首先，公共类Foo: IFoo<T>{}不能编译，因为你需要指定一个类而不是T，但假设你做的事情类似于公共类Foo: IFoo<SomeClass> {}

如果你这样做了

Foo f = new Foo();
IBar<SomeClass> b = f as IBar<SomeClass>;

if(b != null)  //derives from IBar<>
    Blabla();

public interface IFoo<T> : IBar<T> {}
public class Foo : IFoo<Foo> {}

var implementedInterfaces = typeof( Foo ).GetInterfaces();
foreach( var interfaceType in implementedInterfaces ) {
    if ( false == interfaceType.IsGeneric ) { continue; }
    var genericType = interfaceType.GetGenericTypeDefinition();
    if ( genericType == typeof( IFoo<> ) ) {
        // do something !
        break;
    }
}