我也想做同样的事情，偶然发现了这个优秀的帖子。如果您希望使用锚API以编程方式完成此操作，则可以采用这种方式。

总之，在UIScrollView中嵌入UIStackView，并设置UIStackView的锚约束来匹配UIScrollView的锚约束:

stackView.leadingAnchor.constraint(equalTo: scrollView.leadingAnchor).isActive = true
stackView.trailingAnchor.constraint(equalTo: scrollView.trailingAnchor).isActive = true
stackView.bottomAnchor.constraint(equalTo: scrollView.bottomAnchor).isActive = true
stackView.topAnchor.constraint(equalTo: scrollView.topAnchor).isActive = true
stackView.widthAnchor.constraint(equalTo: scrollView.widthAnchor).isActive = true

这里投票最多的答案中的约束条件对我来说是有效的，我已经将在我的故事板中创建的约束条件的图像粘贴在下面。

我确实提到了两个问题，但其他人应该注意:

After adding constraints similar to those in in the accepted answer, I'd get the red autolayout error Need constraints for: X position or width. This was solved by adding a UILabel as a subview of the stack view. I'm adding the subviews programmatically, so I originally had no subviews on the storyboard. To get rid of the autolayout errors, add a subview to the storyboard, then remove it on load before adding your real subviews and constraints. I originally attempted to add UIButtons to the UIStackView. The buttons and views would load, but the scroll view would not scroll. This was solved by adding UILabels to the Stack View instead of buttons. Using the same constraints, this view hierarchy with the UILabels scrolls but the UIButtons does not. I'm confused by this issue, as the UIButtons do seem to have an IntrinsicContentSize (used by the Stack View). If anyone knows why the buttons don't work, I'd love to know why.

下面是我的视图层次结构和约束，供参考:

水平滚动(UIScrollView中的UIStackView)

用于水平滚动。首先，创建一个UIStackView和一个UIScrollView，并按以下方式将它们添加到您的视图中:

let scrollView = UIScrollView()
let stackView = UIStackView()

scrollView.addSubview(stackView)
view.addSubview(scrollView)

记住在UIStackView和UIScrollView上设置translatesAutoresizingMaskIntoConstraints为false:

stackView.translatesAutoresizingMaskIntoConstraints = false
scrollView.translatesAutoresizingMaskIntoConstraints = false

为了让一切正常工作，UIStackView的尾随，领先，顶部和底部锚应该等于UIScrollView锚:

stackView.leadingAnchor.constraint(equalTo: scrollView.leadingAnchor).isActive = true
stackView.trailingAnchor.constraint(equalTo: scrollView.trailingAnchor).isActive = true
stackView.topAnchor.constraint(equalTo: scrollView.topAnchor).isActive = true
stackView.bottomAnchor.constraint(equalTo: scrollView.bottomAnchor).isActive = true

但是UIStackView的宽度锚点必须等于或大于UIScrollView锚点的宽度:

stackView.widthAnchor.constraint(greaterThanOrEqualTo: scrollView.widthAnchor).isActive = true

现在锚定你的UIScrollView，例如:

scrollView.heightAnchor.constraint(equalToConstant: 80).isActive = true
scrollView.widthAnchor.constraint(equalTo: view.widthAnchor).isActive = true

scrollView.bottomAnchor.constraint(equalTo:view.safeAreaLayoutGuide.bottomAnchor).isActive = true
scrollView.leadingAnchor.constraint(equalTo:view.leadingAnchor).isActive = true
scrollView.trailingAnchor.constraint(equalTo:view.trailingAnchor).isActive = true 

接下来，我建议尝试以下设置UIStackView对齐和分布:

topicStackView.axis = .horizontal
topicStackView.distribution = .equalCentering
topicStackView.alignment = .center

topicStackView.spacing = 10

最后，你需要使用addArrangedSubview:方法来添加子视图到你的UIStackView。

文本Insets

另一个你可能会发现有用的特性是，因为UIStackView保存在UIScrollView中，你现在可以访问文本insets，使事情看起来更漂亮一点。

let inset:CGFloat = 20
scrollView.contentInset.left = inset
scrollView.contentInset.right = inset

// remember if you're using insets then reduce the width of your stack view to match
stackView.widthAnchor.constraint(greaterThanOrEqualTo: topicScrollView.widthAnchor, constant: -inset*2).isActive = true

First and foremost design your view, preferably in something like Sketch or get an idea of what do you want as a scrollable content. After this make the view controller free form (choose from attribute inspector) and set height and width as per the intrinsic content size of your view (to be chosen from the size inspector). After this in the view controller put a scroll view and this is a logic, which I have found to be working almost all the times in iOS (it may require going through the documentation of that view class which one can obtain via command + click on that class or via googling) If you are working with two or more views then first start with a view, which has been introduced earlier or is more primitive and then go to the view which has been introduced later or is more modern. So here since scroll view has been introduced first, start with the scroll view first and then go to the stack view. Here put scroll view constraints to zero in all direction vis-a-vis its super view. Put all your views inside this scroll view and then put them in stack view.

当使用堆栈视图时

First start with grounds up(bottoms up approach), ie., if you have labels, text fields and images in your view, then lay out these views first (inside the scroll view) and after that put them in the stack view. After that tweak the property of stack view. If desired view is still not achieved, then use another stack view. If still not achieved then play with compression resistance or content hugging priority. After this add constraints to the stack view. Also think of using an empty UIView as filler view, if all of the above is not giving satisfactory results.

在创建视图之后，在母堆栈视图和滚动视图之间放置一个约束，同时约束子堆栈视图和母堆栈视图。 希望这个时候它能正常工作，否则你可能会从Xcode得到一个警告，给出建议，阅读它所说的并执行这些建议。希望现在你应该有一个工作视图按照你的期望:)。

如果有人正在寻找一个没有代码的解决方案，我创建了一个例子来完成这完全在故事板，使用自动布局。

你可以从github上得到。

基本上，要重新创建这个示例(用于垂直滚动):

创建一个UIScrollView，并设置它的约束。 添加一个UIStackView到UIScrollView 设置约束:前导，后尾，顶部和底部应该等于UIScrollView中的约束 在UIStackView和UIScrollView之间设置一个等宽约束。 在UIStackView上设置轴=垂直，对齐=填充，分布=等间距，间距= 0 添加一些uiview到UIStackView 运行

在第4步中将宽度交换为高度，并在第5步中设置轴=水平，以获得水平的UIStackView。

正如Eik所说，UIStackView和UIScrollView很好地结合在一起。

关键是UIStackView处理不同内容的可变高度/宽度，然后UIScrollView做它的工作很好地滚动/反弹内容:

override func viewDidLayoutSubviews() {
    super.viewDidLayoutSubviews()
    scrollView.contentSize = CGSize(width: stackView.frame.width, height: stackView.frame.height)       
}