哦，表演太恐怖了! 答案有点过时了，但仍然……

public static class StringUtils
{
    #region Private members

    [ThreadStatic]
    private static StringBuilder m_ReplaceSB;

    private static StringBuilder GetReplaceSB(int capacity)
    {
        var result = m_ReplaceSB;

        if (null == result)
        {
            result = new StringBuilder(capacity);
            m_ReplaceSB = result;
        }
        else
        {
            result.Clear();
            result.EnsureCapacity(capacity);
        }

        return result;
    }


    public static string ReplaceAny(this string s, char replaceWith, params char[] chars)
    {
        if (null == chars)
            return s;

        if (null == s)
            return null;

        StringBuilder sb = null;

        for (int i = 0, count = s.Length; i < count; i++)
        {
            var temp = s[i];
            var replace = false;

            for (int j = 0, cc = chars.Length; j < cc; j++)
                if (temp == chars[j])
                {
                    if (null == sb)
                    {
                        sb = GetReplaceSB(count);
                        if (i > 0)
                            sb.Append(s, 0, i);
                    }

                    replace = true;
                    break;
                }

            if (replace)
                sb.Append(replaceWith);
            else
                if (null != sb)
                    sb.Append(temp);
        }

        return null == sb ? s : sb.ToString();
    }
}

就性能而言，这可能不是最好的解决方案，但它确实有效。

var str = "filename:with&bad$separators.txt";
char[] charArray = new char[] { '#', '%', '&', '{', '}', '\\', '<', '>', '*', '?', '/', ' ', '$', '!', '\'', '"', ':', '@' };
foreach (var singleChar in charArray)
{
   str = str.Replace(singleChar, '_');
}

你可以使用Linq的Aggregate函数:

string s = "the\nquick\tbrown\rdog,jumped;over the lazy fox.";
char[] chars = new char[] { ' ', ';', ',', '\r', '\t', '\n' };
string snew = chars.Aggregate(s, (c1, c2) => c1.Replace(c2, '\n'));

下面是扩展方法:

public static string ReplaceAll(this string seed, char[] chars, char replacementCharacter)
{
    return chars.Aggregate(seed, (str, cItem) => str.Replace(cItem, replacementCharacter));
}

扩展方法使用示例:

string snew = s.ReplaceAll(chars, '\n');

如果你觉得自己特别聪明，不想使用Regex:

char[] separators = new char[]{' ',';',',','\r','\t','\n'};

string s = "this;is,\ra\t\n\n\ntest";
string[] temp = s.Split(separators, StringSplitOptions.RemoveEmptyEntries);
s = String.Join("\n", temp);

您也可以用一个扩展方法来包装它。

编辑:或者只要等2分钟，我还是会把它写完:)

public static class ExtensionMethods
{
   public static string Replace(this string s, char[] separators, string newVal)
   {
       string[] temp;

       temp = s.Split(separators, StringSplitOptions.RemoveEmptyEntries);
       return String.Join( newVal, temp );
   }
}

和瞧...

char[] separators = new char[]{' ',';',',','\r','\t','\n'};
string s = "this;is,\ra\t\n\n\ntest";

s = s.Replace(separators, "\n");

string ToBeReplaceCharacters = @"~()@#$%&+,'"<>|;\/*?";
string fileName = "filename;with<bad:separators?";

foreach (var RepChar in ToBeReplaceCharacters)
{
    fileName = fileName.Replace(RepChar.ToString(), "");
}

你也可以简单地写这些字符串扩展方法，并把它们放在你的解决方案中的某个地方:

using System.Text;

public static class StringExtensions
{
    public static string ReplaceAll(this string original, string toBeReplaced, string newValue)
    {
        if (string.IsNullOrEmpty(original) || string.IsNullOrEmpty(toBeReplaced)) return original;
        if (newValue == null) newValue = string.Empty;
        StringBuilder sb = new StringBuilder();
        foreach (char ch in original)
        {
            if (toBeReplaced.IndexOf(ch) < 0) sb.Append(ch);
            else sb.Append(newValue);
        }
        return sb.ToString();
    }

    public static string ReplaceAll(this string original, string[] toBeReplaced, string newValue)
    {
        if (string.IsNullOrEmpty(original) || toBeReplaced == null || toBeReplaced.Length <= 0) return original;
        if (newValue == null) newValue = string.Empty;
        foreach (string str in toBeReplaced)
            if (!string.IsNullOrEmpty(str))
                original = original.Replace(str, newValue);
        return original;
    }
}

这样称呼他们:

"ABCDE".ReplaceAll("ACE", "xy");

xyBxyDxy

这:

"ABCDEF".ReplaceAll(new string[] { "AB", "DE", "EF" }, "xy");

xyCxyF