我在Visual Studio 2015上执行Install-Package Modernizr时遇到了类似的问题。我通过以下步骤解决了这个问题:

Download the package from its online source. Go to Tools/NuGet Package Manager/Package Manager Settings. Select Package Sources from the window. Add a new package source by clicking on the + sign. Enter a name and source location by clicking on ... (triple dot) sign. Make sure that only the package source that you've just added is checked. Uncheck all the other package sources. Go to Package Manager Console and type Install-Package Modernizr. Visual Studio 2015 installs the package automatically and creates Scripts and packages folders in your root folder.

我希望同样的解决方案在安装其他包时也能起作用。

似乎Nuget仍然使用代理脚本地址(对于我们的VPN)，即使代理设置被禁用。我删除了脚本地址，它工作。

在我的例子中，问题在于我是在旧的Win7虚拟机上构建的。

我从https://github.com/NuGet/NuGetGallery/issues/8176#issuecomment-683923724找到了这个修复:

nuget.org started enforcing the use of TLS 1.2 (and dropped support for TLS 1.1 and 1.0) earlier this year. Windows 7 has TLS 1.2 disabled by default (check the DisabledByDefault value under HKLM\SYSTEM\CurrentControlSet\Control\SecurityProviders\SCHANNEL\Protocols\TLS 1.2\Client in your registry). To enable the support, please make sure you have an update (*) installed and switch the support on: reg add HKLM\SYSTEM\CurrentControlSet\Control\SecurityProviders\SCHANNEL\Protocols\TLS 1.2\Client" /v DisabledByDefault /t REG_DWORD /d 0 /f /reg:32 reg add "HKLM\SYSTEM\CurrentControlSet\Control\SecurityProviders\SCHANNEL\Protocols\TLS 1.2\Client" /v DisabledByDefault /t REG_DWORD /d 0 /f /reg:64 reg add "HKLM\SYSTEM\CurrentControlSet\Control\SecurityProviders\SCHANNEL\Protocols\TLS 1.2\Client" /v Enabled /t REG_DWORD /d 1 /f /reg:32 reg add "HKLM\SYSTEM\CurrentControlSet\Control\SecurityProviders\SCHANNEL\Protocols\TLS 1.2\Client" /v Enabled /t REG_DWORD /d 1 /f /reg:64

(*)更新指的是Microsoft kb3140245: Windows 7更新(KB3140245)

我安装了更新，重新启动(按照更新的要求)，添加了那些注册表项，然后Nuget就可以正常工作了。

在我的情况下，我必须在Visual studio Options->NugetPAckageManager->sources中添加源 然后重新启动visual studio命令提示符

那些说要删除Nuget的答案。如果您正在使用自定义提要，Config将不起作用。如果您正在使用自定义提要，则需要编辑Nuget。配置文件指向自定义提要的索引。

你需要在Nuget中添加代理设置。配置文件。有关详细信息，请参阅此链接:Nuget配置部分和Nuget代理设置。