我已经为任意数量的列创建了基于bootstrap定义的SASS mixin定义(个人而言，除了12列，我使用8、10和24列):

// Extended bootstrap grid system
//
// Framework grid generation
//
// Based on Bootstrap 'bootstrap/_grid-framework.scss'. Generates classes in form of `.col-(size)-x-num` of width x/num.

@mixin make-extended-grid-columns($num-columns, $i: 1, $list: ".col-xs-#{$i}-#{$num-columns}, .col-sm-#{$i}-#{$num-columns}, .col-md-#{$i}-#{$num-columns}, .col-lg-#{$i}-#{$num-columns}") {
    @for $i from (1 + 1) through $num-columns {
        $list: "#{$list}, .col-xs-#{$i}-#{$num-columns}, .col-sm-#{$i}-#{$num-columns}, .col-md-#{$i}-#{$num-columns}, .col-lg-#{$i}-#{$num-columns}";
    }
    #{$list} {
        position: relative;
        min-height: 1px;
        padding-left:  ($grid-gutter-width / 2);
        padding-right: ($grid-gutter-width / 2);
    }
}


@mixin float-extended-grid-columns($class, $num-columns, $i: 1, $list: ".col-#{$class}-#{$i}-#{$num-columns}") {
    @for $i from (1 + 1) through $num-columns {
        $list: "#{$list}, .col-#{$class}-#{$i}-#{$num-columns}";
    }
    #{$list} {
        float: left;
    }
}


@mixin calc-extended-grid-column($index, $num-columns, $class, $type) {
    @if ($type == width) and ($index > 0) {
        .col-#{$class}-#{$index}-#{$num-columns} {
            width: percentage(($index / $num-columns));
        }
    }
    @if ($type == push) and ($index > 0) {
        .col-#{$class}-push-#{$index}-#{$num-columns} {
            left: percentage(($index / $num-columns));
        }
    }
    @if ($type == pull) and ($index > 0) {
        .col-#{$class}-pull-#{$index}-#{$num-columns} {
            right: percentage(($index / $num-columns));
        }
    }
    @if ($type == offset) and ($index > 0) {
        .col-#{$class}-offset-#{$index}-#{$num-columns} {
            margin-left: percentage(($index / $num-columns));
        }
    }
}

@mixin loop-extended-grid-columns($num-columns, $class, $type) {
    @for $i from 1 through $num-columns - 1 {
        @include calc-extended-grid-column($i, $num-columns, $class, $type);
    }
}

@mixin make-extended-grid($class, $num-columns) {
    @include float-extended-grid-columns($class, $num-columns);
    @include loop-extended-grid-columns($num-columns, $class, width);
    @include loop-extended-grid-columns($num-columns, $class, pull);
    @include loop-extended-grid-columns($num-columns, $class, push);
    @include loop-extended-grid-columns($num-columns, $class, offset);
}

你可以简单地创建类:

$possible-number-extended-grid-columns: 8, 10, 24;

@each $num-columns in $possible-number-extended-grid-columns {

  // Columns

  @include make-extended-grid-columns($num-columns);

  // Extra small grid

  @include make-extended-grid(xs, $num-columns);

  // Small grid

  @media (min-width: $screen-sm-min) {
    @include make-extended-grid(sm, $num-columns);
  }

  // Medium grid

  @media (min-width: $screen-md-min) {
    @include make-extended-grid(md, $num-columns);
  }

  // Large grid

  @media (min-width: $screen-lg-min) {
    @include make-extended-grid(lg, $num-columns);
  }

}

我希望有人会觉得它有用

下面是@machineaddict和@Mafnah回答的组合，为Bootstrap 3重写(到目前为止对我来说很好):

@media (min-width: 768px){
    .fivecolumns .col-md-2, .fivecolumns .col-sm-2, .fivecolumns .col-lg-2  {
        width: 20%;
        *width: 20%;
    }
}
@media (min-width: 1200px) {
    .fivecolumns .col-md-2, .fivecolumns .col-sm-2, .fivecolumns .col-lg-2 {
        width: 20%;
        *width: 20%;
    }
}
@media (min-width: 768px) and (max-width: 979px) {
    .fivecolumns .col-md-2, .fivecolumns .col-sm-2, .fivecolumns .col-lg-2 {
        width: 20%;
        *width: 20%;
    }
}

我对这个问题的首选方法是基于make-grid-columns mixin，利用现有的Bootstrap变量创建一个SASS mixin。

// Custom Grid Columns
// 
// $name - determines the class names: eg. ".col-5ths, .col-sm-5ths ..."
// $size - determines the width (2.4 is one fifth of 12, the default number of columns)
@mixin custom-grid-columns($name, $size, $grid-columns: $grid-columns, $breakpoints: $grid-breakpoints) {
    $columns: round($grid-columns / $size);

    %custom-grid-column {
        @include make-col-ready();
    }

    @each $breakpoint in map-keys($breakpoints) {
        $infix: breakpoint-infix($breakpoint, $breakpoints);

        .col#{$infix}-#{$name} {
            @extend %custom-grid-column;
        }

        @include media-breakpoint-up($breakpoint, $breakpoints) {
            // Create column
            .col#{$infix}-#{$name} {
                @include make-col($size);
            }

            // Create offset
            @if not ($infix=="") {
                .offset#{$infix}-#{$name} {
                    @include make-col-offset($size);
                }
            }
        }
    }
}

然后可以调用mixin来生成自定义列类和偏移量类。

@include custom-grid-columns('5ths', 2.4);

一个解决方案，不需要大量的CSS，也不调整bootstrap默认12col布局:

http://jsfiddle.net/0ufdyeur/1/

HTML:

<div class="stretch">
  <div class="col-lg-2"></div>
  <div class="col-lg-2"></div>
  <div class="col-lg-2"></div>
  <div class="col-lg-2"></div>
  <div class="col-lg-2"></div>
</div>

CSS:

@media (min-width: 1200px) { /*if not lg, change this criteria*/
  .stretch{
    width: 120%; /*the actual trick*/
  }
}

为5列布局创建自定义引导下载

进入Bootstrap 2.3.2(或Bootstrap 3)自定义页面，设置以下变量(不要输入分号):

@gridColumns:           5;
@gridColumnWidth:       172px;
@gridColumnWidth1200:   210px;
@gridColumnWidth768:    128px;
@gridGutterWidth768:    21px;

下载您的构建。这个网格将适合默认的容器，(几乎)保留默认的沟槽宽度。

注意:如果你使用LESS，更新变量。而不是更少。

对于@lightswitch的回答，如果我们需要使用更少迭代的5列网格

.make-fifth-col(@index) when (@index > 0) {
  @class-name: ~".col-md-5th-@{index}";

  @{class-name} {
    .make-md-column(1.2*@index);
  }

  .make-fifth-col(@index - 1);
}

.make-fifth-col(10);

这将生成css类。col-md-5th-1, col-md-5th-2, col-md-5th-3，等等，对应10%，20%，30%…分别