保持原始的12列引导，不要自定义它。你唯一需要做的修改是一些css之后的原始引导响应css，像这样:

下面的代码已经为Bootstrap 2.3.2进行了测试:

<style type="text/css">
/* start of modification for 5 columns */
@media (min-width: 768px){
    .fivecolumns .span2 {
        width: 18.297872340425532%;
        *width: 18.2234042553191494%;
    }
}
@media (min-width: 1200px) {
    .fivecolumns .span2 {
        width: 17.9487179487179488%;
        *width: 17.87424986361156592%;
    }
}
@media (min-width: 768px) and (max-width: 979px) {
    .fivecolumns .span2 {
        width: 17.79005524861878448%;
        *width: 17.7155871635124022%;
    }
}
/* end of modification for 5 columns */
</style>

和html:

<div class="row-fluid fivecolumns">
    <div class="span2">
        <h2>Heading</h2>
        <p>Donec id elit non mi porta gravida at eget metus. Fusce dapibus, tellus ac cursus commodo, tortor mauris condimentum nibh, ut fermentum massa justo sit amet risus. Etiam porta sem malesuada magna mollis euismod. Donec sed odio dui. </p>
        <p><a class="btn" href="#">View details &raquo;</a></p>
    </div>
    <div class="span2">
        <h2>Heading</h2>
        <p>Donec id elit non mi porta gravida at eget metus. Fusce dapibus, tellus ac cursus commodo, tortor mauris condimentum nibh, ut fermentum massa justo sit amet risus. Etiam porta sem malesuada magna mollis euismod. Donec sed odio dui. </p>
        <p><a class="btn" href="#">View details &raquo;</a></p>
    </div>
    <div class="span2">
        <h2>Heading</h2>
        <p>Donec sed odio dui. Cras justo odio, dapibus ac facilisis in, egestas eget quam. Vestibulum id ligula porta felis euismod semper. Fusce dapibus, tellus ac cursus commodo, tortor mauris condimentum nibh, ut fermentum massa justo sit amet risus.</p>
        <p><a class="btn" href="#">View details &raquo;</a></p>
    </div>
    <div class="span2">
        <h2>Heading</h2>
        <p>Donec sed odio dui. Cras justo odio, dapibus ac facilisis in, egestas eget quam. Vestibulum id ligula porta felis euismod semper. Fusce dapibus, tellus ac cursus commodo, tortor mauris condimentum nibh, ut fermentum massa justo sit amet risus.</p>
        <p><a class="btn" href="#">View details &raquo;</a></p>
    </div>
    <div class="span2">
        <h2>Heading</h2>
        <p>Donec sed odio dui. Cras justo odio, dapibus ac facilisis in, egestas eget quam. Vestibulum id ligula porta felis euismod semper. Fusce dapibus, tellus ac cursus commodo, tortor mauris condimentum nibh, ut fermentum massa justo sit amet risus.</p>
        <p><a class="btn" href="#">View details &raquo;</a></p>
    </div>
</div>

注意:即使span2乘以5不等于12列，你明白了吧:)

可以在这里找到一个工作示例http://jsfiddle.net/v3Uy5/6/

5列布局与Twitter引导风格

.col-xs-15 {
    position: relative;
    min-height: 1px;
    padding-right: 10px;
    padding-left: 10px;
}

.col-xs-15 {
    width: 100%;
    float: left;
}
@media (min-width: 768px) {
.col-xs-15 {
        width: 50%;
        float: left;
    }
}
@media (min-width: 992px) {
    .col-xs-15 {
        width: 20%;
        float: left;
    }
}
@media (min-width: 1200px) {
    .col-xs-15 {
        width: 20%;
        float: left;
    }
}

这个很棒:http://www.ianmccullough.net/5-column-bootstrap-layout/

只做:

<div class="col-xs-2 col-xs-15">

和CSS:

.col-xs-15{
    width:20%;
}

我对Mafnah的答案进行了投票，但再看一遍，如果你保持默认的边际，我建议下面的答案更好。

<div class="equal row-fluid">
    <div class="span2"></div>
    <div class="span2"></div>
    <div class="span2"></div>
    <div class="span2"></div>
    <div class="span2"></div>
</div>

.equal .span2 {
    width: 17.9%;
}

如果你不需要完全相同的列宽度，你可以尝试使用嵌套创建5列:

<div class="container">
    <div class="row">
        <div class="col-xs-5">
            <div class="row">
                <div class="col-xs-6 column">Column 1</div>
                <div class="col-xs-6 column">Column 2</div>
            </div>
        </div>
        <div class="col-xs-7">
            <div class="row">
                <div class="col-xs-4 column">Column 3</div>
                <div class="col-xs-4 column">Column 4</div>
                <div class="col-xs-4 column">Column 5</div>
            </div>
        </div>
    </div>
</div>

斯菲德尔

前两列的宽度为5/12 * 1/2 ~ 20.83%

后三列:7/12 * 1/3 ~ 19.44%

这样的hack在许多情况下给出了可接受的结果，不需要任何CSS更改(我们只使用本机引导类)。

更新2019

引导4.1 +

下面是5个相同的全宽列(没有额外的CSS或SASS)，使用自动布局网格:

<div class="container-fluid">
    <div class="row">
        <div class="col">1</div>
        <div class="col">2</div>
        <div class="col">3</div>
        <div class="col">4</div>
        <div class="col">5</div>
    </div>
</div>

http://codeply.com/go/MJTglTsq9h

这个解决方案是有效的，因为Bootstrap 4现在是flexbox。你可以让5列在相同的.row中使用换行符，如<div class="col-12"></div>或<div class="w-100"></div>每5列。

也请参阅:引导- 5列布局