在MacOS Mojave上，我也没有权限删除/usr/local文件夹(sudo chown -R "$USER":admin /usr/local)。

sudo chown -R "$USER":admin /usr/local/*确实为我工作，但是，改变本地文件夹中的所有权限。

希望这能帮助其他有同样问题的人。

我用这些命令解决了我的问题:

sudo mkdir /usr/local/Cellar
sudo mkdir /usr/local/opt
sudo chown -R $(whoami) /usr/local/Cellar
sudo chown -R $(whoami) /usr/local/opt

macOS High Sierra的新命令，因为不可能咀嚼/usr/local:

bash / zsh:

sudo chown -R $(whoami) $(brew --prefix)/*

鱼:

sudo chown -R (whoami) (brew --prefix)/*

参考:不能chown /usr/local在High Sierra

对于多用户Mac来说，这对我来说是可行的:

sudo chown -R $(whoami):admin $(brew --prefix)/*

如果你想要一个比毯子chown -R更有针对性的方法，你可能会发现这个fix-homebrew脚本很有用:

#!/bin/sh

[ -e `which brew` ] || {
    echo Homebrew doesn\'t appear to be installed.
    exit -1
}

BREW_ROOT="`dirname $(dirname $(which brew))`"
BREW_GROUP=admin
BREW_DIRS=".git bin sbin Library Cellar share etc lib opt CONTRIBUTING.md README.md SUPPORTERS.md"

echo "This script will recursively update the group on the following paths"
echo "to the '${BREW_GROUP}' group and make them group writable:"
echo ""

for dir in $BREW_DIRS ; do {
    [ -e "$BREW_ROOT/$dir" ] && echo "    $BREW_ROOT/$dir "
} ; done

echo ""
echo "It will also stash (and clean) any changes that are currently in the homebrew repo, so that you have a fresh blank-slate."
echo ""

read -p 'Press any key to continue or CTRL-C to abort.'

echo "You may be asked below for your login password."
echo ""

# Non-recursively update the root brew path.
echo Updating "$BREW_ROOT" . . .
sudo chgrp "$BREW_GROUP" "$BREW_ROOT"
sudo chmod g+w "$BREW_ROOT"

# Recursively update the other paths.
for dir in $BREW_DIRS ; do {
    [ -e "$BREW_ROOT/$dir" ] && (
        echo Recursively updating "$BREW_ROOT/$dir" . . .
        sudo chmod -R g+w "$BREW_ROOT/$dir"
        sudo chgrp -R "$BREW_GROUP" "$BREW_ROOT/$dir"
    )
} ; done

# Non-distructively move any git crud out of the way
echo Stashing changes in "$BREW_ROOT" . . .
cd $BREW_ROOT
git add .
git stash
git clean -d -f Library

echo Finished.

它不会对用户执行chmod操作，而是将homebrew使用的/usr/local中特定目录的写权限授予管理组(您可能属于该组)。它还会在执行之前准确地告诉你它打算做什么。

我使用了这两个命令并解决了我的问题

sudo chown -R $(whoami) /usr/local

sudo chown -R $(whoami) /usr/local/etc/bash_completion.d /usr/local/lib/python3.7/site-packages /usr/local/share/aclocal /usr/local/share/locale /usr/local/share/man/man7 /usr/local/share/man/man8 /usr/local/share/zsh /usr/local/share/zsh/site-functions /usr/local/var/homebrew/locks