您可以手动更改标签的高度，而不是使用sizeToFit；

CGSize size = [descLabel.text sizeWithFont:descLabel.font constrainedToSize:CGSizeMake(labelWidth, labelHeight)];
CGRect frame = descLabel.frame;
frame.size.height = size.height;    
[yourLabel setFrame:frame];

返回的尺寸将最适合标签的内容。如果标签的高度适合其内容，则内容位于标签中心时不会出现问题。

在发布的所有其他解决方案的基础上，我创建了一个简单的小UILabel子类，在设置其对齐属性时将为您处理垂直对齐。这还将在方向更改时更新标签，将高度约束到文本，并将标签的宽度保持在其原始大小。

.h

@interface VAlignLabel : UILabel
@property (nonatomic, assign) WBZVerticalAlignment alignment;
@end


.m

 -(void)setAlignment:(WBZVerticalAlignment)alignment{

    _alignment = alignment;

    CGSize s = [self.text sizeWithFont:self.font constrainedToSize:CGSizeMake(self.frame.size.width, 9999) lineBreakMode:NSLineBreakByWordWrapping];

    switch (_alignment)
    {
        case wbzLabelAlignmentVerticallyTop:
            self.frame = CGRectMake(self.frame.origin.x, self.frame.origin.y, self.frame.size.width, s.height);
            break;
        case wbzLabelAlignmentVerticallyMiddle:
            self.frame = CGRectMake(self.frame.origin.x, self.frame.origin.y + (self.frame.size.height - s.height)/2, self.frame.size.width, s.height);
            break;
        case wbzLabelAlignmentVerticallyBottom:
            self.frame = CGRectMake(self.frame.origin.x, self.frame.origin.y + (self.frame.size.height - s.height), self.frame.size.width, s.height);
            break;
        default:
            break;
    }
}

-(void)layoutSubviews{
    [self setAlignment:self.alignment];
}

对于Swift 3。。。

@IBDesignable class TopAlignedLabel: UILabel {
    override func drawText(in rect: CGRect) {
        if let stringText = text {
            let stringTextAsNSString = stringText as NSString
            let labelStringSize = stringTextAsNSString.boundingRect(with: CGSize(width: self.frame.width,height: CGFloat.greatestFiniteMagnitude),
                                                                            options: NSStringDrawingOptions.usesLineFragmentOrigin,
                                                                            attributes: [NSFontAttributeName: font],
                                                                            context: nil).size
            super.drawText(in: CGRect(x:0,y: 0,width: self.frame.width, height:ceil(labelStringSize.height)))
        } else {
            super.drawText(in: rect)
        }
    }
    override func prepareForInterfaceBuilder() {
        super.prepareForInterfaceBuilder()
        layer.borderWidth = 1
        layer.borderColor = UIColor.black.cgColor
    }
}

子类UILabel并约束绘图矩形，如下所示：

- (void)drawTextInRect:(CGRect)rect
{
    CGSize sizeThatFits = [self sizeThatFits:rect.size];
    rect.size.height = MIN(rect.size.height, sizeThatFits.height);

    [super drawTextInRect:rect];
}

我尝试了涉及换行填充的解决方案，在某些情况下遇到了错误的行为。根据我的经验，如上所述约束绘图矩形比使用numberOfLines更容易。

P.S.你可以想象一下这样轻松地支持UIViewContentMode：

- (void)drawTextInRect:(CGRect)rect
{
    CGSize sizeThatFits = [self sizeThatFits:rect.size];

    if (self.contentMode == UIViewContentModeTop) {
        rect.size.height = MIN(rect.size.height, sizeThatFits.height);
    }
    else if (self.contentMode == UIViewContentModeBottom) {
        rect.origin.y = MAX(0, rect.size.height - sizeThatFits.height);
        rect.size.height = MIN(rect.size.height, sizeThatFits.height);
    }

    [super drawTextInRect:rect];
}

在swift中，

let myLabel:UILabel！

使标签的文本适合屏幕，并位于顶部

myLabel.sizeToFit（）

使标签字体适合屏幕宽度或特定宽度大小。

myLabel.adjustsFontSizeToFitWidth=是

以及标签的一些文本对齐：

myLabel.textAlignment=.center

myLabel.textAlignment=左侧

myLabel.textAlignment=右侧

myLabel.textAlignment=.自然

myLabel.textAlignment=两端对齐

我重复了戴莱辛的建议，并添加了一个UIEdgeInset，以允许调整边距。周围环境不错。

- (id)init
{
    if (self = [super init]) {
        contentEdgeInsets = UIEdgeInsetsZero;
    }

    return self;
}

- (void)layoutSubviews
{
    CGRect localBounds = self.bounds;
    localBounds = CGRectMake(MAX(0, localBounds.origin.x + contentEdgeInsets.left), 
                             MAX(0, localBounds.origin.y + contentEdgeInsets.top), 
                             MIN(localBounds.size.width, localBounds.size.width - (contentEdgeInsets.left + contentEdgeInsets.right)), 
                             MIN(localBounds.size.height, localBounds.size.height - (contentEdgeInsets.top + contentEdgeInsets.bottom)));

    for (UIView *subview in self.subviews) {
        if ([subview isKindOfClass:[UILabel class]]) {
            UILabel *label = (UILabel*)subview;
            CGSize lineSize = [label.text sizeWithFont:label.font];
            CGSize sizeForText = [label.text sizeWithFont:label.font constrainedToSize:localBounds.size lineBreakMode:label.lineBreakMode];

            NSInteger numberOfLines = ceilf(sizeForText.height/lineSize.height);

            label.numberOfLines = numberOfLines;
            label.frame = CGRectMake(MAX(0, contentEdgeInsets.left), MAX(0, contentEdgeInsets.top), localBounds.size.width, MIN(localBounds.size.height, lineSize.height * numberOfLines)); 
        }
    }
}