通过设置Pragma：无缓存

对于ASP.NET Core，创建一个简单的中间件类：

public class NoCacheMiddleware
{
    private readonly RequestDelegate m_next;

    public NoCacheMiddleware( RequestDelegate next )
    {
        m_next = next;
    }

    public async Task Invoke( HttpContext httpContext )
    {
        httpContext.Response.OnStarting( ( state ) =>
        {
            // ref: http://stackoverflow.com/questions/49547/making-sure-a-web-page-is-not-cached-across-all-browsers
            httpContext.Response.Headers.Append( "Cache-Control", "no-cache, no-store, must-revalidate" );
            httpContext.Response.Headers.Append( "Pragma", "no-cache" );
            httpContext.Response.Headers.Append( "Expires", "0" );
            return Task.FromResult( 0 );
        }, null );

        await m_next.Invoke( httpContext );
    }
}

然后在Startup.cs中注册

app.UseMiddleware<NoCacheMiddleware>();

确保在以下位置添加此

app.UseStaticFiles();

您可以在IIS中使用位置块来设置单个文件，而不是整个应用程序获取缓存

 <location path="index.html">
    <system.webServer>
      <httpProtocol>
        <customHeaders>
          <add name="Cache-Control" value="no-cache" />
        </customHeaders>
      </httpProtocol>
    </system.webServer>
  </location>

如果您面临通过SSL和cache:MS Office文件的IE6-IE8下载问题，则可以在POST请求时使用cache:private、no store header和return file。它起作用了。

//In .net MVC
[OutputCache(NoStore = true, Duration = 0, VaryByParam = "*")]
public ActionResult FareListInfo(long id)
{
}

// In .net webform
<%@ OutputCache NoStore="true" Duration="0" VaryByParam="*" %>

完成BalusC->答案如果您使用的是perl，则可以使用CGI添加HTTP标头。

使用Perl：

Use CGI;    
sub set_new_query() {
        binmode STDOUT, ":utf8";
        die if defined $query;
        $query = CGI->new();
        print $query->header(
                        -expires       => 'Sat, 26 Jul 1997 05:00:00 GMT',
                        -Pragma        => 'no-cache',
                        -Cache_Control => join(', ', qw(
                                            private
                                            no-cache
                                            no-store
                                            must-revalidate
                                            max-age=0
                                            pre-check=0
                                            post-check=0 
                                           ))
        );
    }

使用apachehttpd.conf

<FilesMatch "\.(html|htm|js|css|pl)$">
FileETag None
<ifModule mod_headers.c>
Header unset ETag
Header set Cache-Control "max-age=0, no-cache, no-store, must-revalidate"
Header set Pragma "no-cache"
Header set Expires "Wed, 11 Jan 1984 05:00:00 GMT"
</ifModule>

注意：当我尝试使用html META时，浏览器忽略了它们并缓存了页面。