我想到的一个简单的解决办法是:

for i in MyList:
    # Check if 'i' is the last element in the list
    if i == MyList[-1]:
        # Do something different for the last
    else:
        # Do something for all other elements

第二个同样简单的解决方法是使用计数器:

# Count the no. of elements in the list
ListLength = len(MyList)
# Initialize a counter
count = 0

for i in MyList:
    # increment counter
    count += 1
    # Check if 'i' is the last element in the list
    # by using the counter
    if count == ListLength:
        # Do something different for the last
    else:
        # Do something for all other elements

假设input是一个迭代器，下面是使用itertools中的tee和izip的方法:

from itertools import tee, izip
items, between = tee(input_iterator, 2)  # Input must be an iterator.
first = items.next()
do_to_every_item(first)  # All "do to every" operations done to first item go here.
for i, b in izip(items, between):
    do_between_items(b)  # All "between" operations go here.
    do_to_every_item(i)  # All "do to every" operations go here.

演示:

>>> def do_every(x): print "E", x
...
>>> def do_between(x): print "B", x
...
>>> test_input = iter(range(5))
>>>
>>> from itertools import tee, izip
>>>
>>> items, between = tee(test_input, 2)
>>> first = items.next()
>>> do_every(first)
E 0
>>> for i,b in izip(items, between):
...     do_between(b)
...     do_every(i)
...
B 0
E 1
B 1
E 2
B 2
E 3
B 3
E 4
>>>

数一次项目，并跟上剩余项目的数量:

remaining = len(data_list)
for data in data_list:
    code_that_is_done_for_every_element

    remaining -= 1
    if remaining:
        code_that_is_done_between_elements

这种方法只计算一次列表的长度。本页上的许多解决方案似乎都假定长度是预先不可用的，但这不是您的问题的一部分。如果你有长度，就用它。

只需检查data是否与data_list (data_list[-1])中的最后一个数据不相同。

for data in data_list:
    code_that_is_done_for_every_element
    if data != data_list[- 1]:
        code_that_is_done_between_elements

这类似于Ants Aasma的方法，但没有使用itertools模块。它也是一个滞后迭代器，它可以提前查找迭代器流中的单个元素:

def last_iter(it):
    # Ensure it's an iterator and get the first field
    it = iter(it)
    prev = next(it)
    for item in it:
        # Lag by one item so I know I'm not at the end
        yield 0, prev
        prev = item
    # Last item
    yield 1, prev

def test(data):
    result = list(last_iter(data))
    if not result:
        return
    if len(result) > 1:
        assert set(x[0] for x in result[:-1]) == set([0]), result
    assert result[-1][0] == 1

test([])
test([1])
test([1, 2])
test(range(5))
test(xrange(4))

for is_last, item in last_iter("Hi!"):
    print is_last, item

除了向上数，你也可以向下数:

  nrToProcess = len(list)
  for s in list:
    s.doStuff()
    nrToProcess -= 1
    if nrToProcess==0:  # this is the last one
      s.doSpecialStuff()